| # | Title | Journal | Year | Citations |
|---|
| 1 | A reference panel of 64,976 haplotypes for genotype imputation | Nature Genetics | 2016 | 2,421 |
| 2 | Atorvastatin Reduces the Ability of Clopidogrel to Inhibit Platelet Aggregation | Circulation | 2003 | 656 |
| 3 | Biobank-driven genomic discovery yields new insight into atrial fibrillation biology | Nature Genetics | 2018 | 547 |
| 4 | Conscious Processing and the Global Neuronal Workspace Hypothesis | Neuron | 2020 | 487 |
| 5 | The Metabolism of Clopidogrel Is Catalyzed by Human Cytochrome P450 3A and Is Inhibited by Atorvastatin | Drug Metabolism and Disposition | 2003 | 354 |
| 6 | Routine Clinical Practice Effectiveness of the Glidescope in Difficult Airway Management | Anesthesiology | 2011 | 351 |
| 7 | Intraoperative ketamine for prevention of postoperative delirium or pain after major surgery in older adults: an international, multicentre, double-blind, randomised clinical trial | Lancet, The | 2017 | 346 |
| 8 | Skeletal Localization and Neutralization of the SDF-1(CXCL12)/CXCR4 Axis Blocks Prostate Cancer Metastasis and Growth in Osseous Sites In Vivo | Journal of Bone and Mineral Research | 2005 | 345 |
| 9 | Overlapping Chronic Pain Conditions: Implications for Diagnosis and Classification | Journal of Pain | 2016 | 329 |
| 10 | Cytokines and sleep | Sleep Medicine Reviews | 2005 | 327 |
| 11 | Wnt10b Inhibits Development of White and Brown Adipose Tissues | Journal of Biological Chemistry | 2004 | 316 |
| 12 | Association of Opioid Prescribing With Opioid Consumption After Surgery in Michigan | JAMA Surgery | 2019 | 275 |
| 13 | Traditional Chinese acupuncture and placebo (sham) acupuncture are differentiated by their effects on μ-opioid receptors (MORs) | NeuroImage | 2009 | 265 |
| 14 | The Science of Fibromyalgia | Mayo Clinic Proceedings | 2011 | 252 |
| 15 | In Vivo Measurements of Neurotransmitters by Microdialysis Sampling | Analytical Chemistry | 2006 | 251 |
| 16 | Perineural Dexmedetomidine Added to Ropivacaine for Sciatic Nerve Block in Rats Prolongs the Duration of Analgesia by Blocking the Hyperpolarization-activated Cation Current | Anesthesiology | 2011 | 240 |
| 17 | The Reliability and Validity of the Face, Legs, Activity, Cry, Consolability Observational Tool as a Measure of Pain in Children with Cognitive Impairment | Anesthesia and Analgesia | 2002 | 230 |
| 18 | Sleep, Anesthesiology, and the Neurobiology of Arousal State Control | Anesthesiology | 2005 | 228 |
| 19 | Pregabalin Rectifies Aberrant Brain Chemistry, Connectivity, and Functional Response in Chronic Pain Patients | Anesthesiology | 2013 | 225 |
| 20 | Paradoxes in Acupuncture Research: Strategies for Moving Forward | Evidence-based Complementary and Alternative Medicine | 2011 | 220 |
| 21 | Cancer‐related chronic pain | Cancer | 2011 | 215 |
| 22 | Collagen Degradation in Aged/Photodamaged Skin In Vivo and After Exposure to Matrix Metalloproteinase-1 In Vitro | Journal of Investigative Dermatology | 2003 | 213 |
| 23 | Oxygen-mediated regulation of skeletal muscle satellite cell proliferation and adipogenesis in culture | Journal of Cellular Physiology | 2001 | 204 |
| 24 | Near-Infrared spectroscopy: Theory and applications | Journal of Cardiothoracic and Vascular Anesthesia | 1996 | 199 |
| 25 | Critical Oxygen Delivery in Conscious Humans Is Less Than 7.3 ml O2· kg−1· min−1 | Anesthesiology | 2000 | 186 |
| 26 | The Status and Future of Acupuncture Mechanism Research | Journal of Alternative and Complementary Medicine | 2008 | 186 |
| 27 | Sugammadex versus Neostigmine for Reversal of Neuromuscular Blockade and Postoperative Pulmonary Complications (STRONGER) | Anesthesiology | 2020 | 184 |
| 28 | Fibromyalgia: from pathophysiology to therapy | Nature Reviews Rheumatology | 2011 | 181 |
| 29 | Clopidogrel–Drug Interactions | Journal of the American College of Cardiology | 2011 | 178 |
| 30 | Central sensitisation in chronic pain conditions: latest discoveries and their potential for precision medicine | Lancet Rheumatology, The | 2021 | 176 |
| 31 | Independent Predictors and Outcomes of Unanticipated Early Postoperative Tracheal Intubation after Nonemergent, Noncardiac Surgery | Anesthesiology | 2011 | 167 |
| 32 | Maximal Oxidative Capacity during Exercise Is Associated with Skeletal Muscle Fuel Selection and Dynamic Changes in Mitochondrial Protein Acetylation | Cell Metabolism | 2015 | 165 |
| 33 | Perineural Dexmedetomidine Added to Ropivacaine Causes a Dose-dependent Increase in the Duration of Thermal Antinociception in Sciatic Nerve Block in Rat | Anesthesiology | 2009 | 163 |
| 34 | How do pediatric anesthesiologists define intraoperative hypotension? | Paediatric Anaesthesia | 2009 | 152 |
| 35 | Assessment of physical function and participation in chronic pain clinical trials: IMMPACT/OMERACT recommendations | Pain | 2016 | 152 |
| 36 | Quantifying the impact of health IT implementations on clinical workflow: a new methodological perspective | Journal of the American Medical Informatics Association: JAMIA | 2010 | 145 |
| 37 | Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility | Nature Genetics | 2020 | 138 |
| 38 | Preoperative Serum Potassium Levels and Perioperative Outcomes in Cardiac Surgery Patients | JAMA - Journal of the American Medical Association | 1999 | 136 |
| 39 | Predictors and Clinical Outcomes from Failed Laryngeal Mask Airway Unique™ | Anesthesiology | 2012 | 133 |
| 40 | Adenosine A1and A2AReceptors in Mouse Prefrontal Cortex Modulate Acetylcholine Release and Behavioral Arousal | Journal of Neuroscience | 2009 | 130 |
| 41 | A Framework for Fibromyalgia Management for Primary Care Providers | Mayo Clinic Proceedings | 2012 | 130 |
| 42 | Endogenous opioidergic dysregulation of pain in fibromyalgia: a PET and fMRI study | Pain | 2016 | 130 |
| 43 | Reframing chronic pain as a disease, not a symptom: rationale and implications for pain management | Postgraduate Medicine | 2019 | 127 |
| 44 | Basal forebrain acetylcholine release during REM sleep is significantly greater than during waking | American Journal of Physiology - Regulatory Integrative and Comparative Physiology | 2001 | 125 |
| 45 | Neck Circumference as a Screening Measure for Identifying Children With High Body Mass Index | Pediatrics | 2010 | 125 |
| 46 | Operative Outcomes of Multiple-Arterial Versus Single-Arterial Coronary Bypass Grafting | Annals of Thoracic Surgery | 2018 | 121 |
| 47 | Model Selection in Magnetic Resonance Imaging Measurements of Vascular Permeability: Gadomer in a 9L Model of Rat Cerebral Tumor | Journal of Cerebral Blood Flow and Metabolism | 2006 | 119 |
| 48 | Pain Mechanisms and Centralized Pain in Temporomandibular Disorders | Journal of Dental Research | 2016 | 118 |
| 49 | Effect of Intraoperative Hyperglycemia During Liver Transplantation | Journal of Surgical Research | 2007 | 116 |
| 50 | Increasing Role of Maternal Immune Activation in Neurodevelopmental Disorders | Frontiers in Behavioral Neuroscience | 2018 | 116 |
