| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Global causes of maternal death: a WHO systematic analysis | The Lancet Global Health | 2014 | 3,772 |
| 3 | An atlas of active enhancers across human cell types and tissues | Nature | 2014 | 2,269 |
| 4 | A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells | Science | 2012 | 2,084 |
| 5 | The Comprehensive Antibiotic Resistance Database | Antimicrobial Agents and Chemotherapy | 2013 | 1,615 |
| 6 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 7 | Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data | BMJ: British Medical Journal | 2017 | 1,408 |
| 8 | Covid-19: risk factors for severe disease and death | BMJ, The | 2020 | 1,242 |
| 9 | PROBAST: A Tool to Assess the Risk of Bias and Applicability of Prediction Model Studies | Annals of Internal Medicine | 2019 | 1,066 |
| 10 | Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility | Nature Genetics | 2014 | 959 |
| 11 | Tackling antibiotic resistance | Nature Reviews Microbiology | 2011 | 919 |
| 12 | Joint European League Against Rheumatism and European Renal Association–European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis | Annals of the Rheumatic Diseases | 2012 | 868 |
| 13 | Systemic lupus erythematosus | Nature Reviews Disease Primers | 2016 | 816 |
| 14 | Minimal/measurable residual disease in AML: a consensus document from the European LeukemiaNet MRD Working Party | Blood | 2018 | 796 |
| 15 | The oral microbiome – an update for oral healthcare professionals | British Dental Journal | 2016 | 782 |
| 16 | Acute appendicitis: modern understanding of pathogenesis, diagnosis, and management | Lancet, The | 2015 | 720 |
| 17 | PROBAST: A Tool to Assess Risk of Bias and Applicability of Prediction Model Studies: Explanation and Elaboration | Annals of Internal Medicine | 2019 | 696 |
| 18 | Prevalence of human papillomavirus in oropharyngeal and nonoropharyngeal head and neck cancer—systematic review and meta‐analysis of trends by time and region | Head and Neck | 2013 | 658 |
| 19 | Global epidemiology of dental caries and severe periodontitis – a comprehensive review | Journal of Clinical Periodontology | 2017 | 633 |
| 20 | Treatment of stage I–III periodontitis—The EFP S3 level clinical practice guideline | Journal of Clinical Periodontology | 2020 | 621 |
| 21 | Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease | Nature Genetics | 2010 | 595 |
| 22 | Hypoxia and metabolic adaptation of cancer cells | Oncogenesis | 2016 | 572 |
| 23 | 2016 Consensus statement on return to sport from the First World Congress in Sports Physical Therapy, Bern | British Journal of Sports Medicine | 2016 | 552 |
| 24 | Distinct fibroblast subsets drive inflammation and damage in arthritis | Nature | 2019 | 550 |
| 25 | A roadmap for interpreting 13 C metabolite labeling patterns from cells | Current Opinion in Biotechnology | 2015 | 513 |
| 26 | Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci | Nature Genetics | 2011 | 481 |
| 27 | Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants | Nature Genetics | 2014 | 475 |
| 28 | Association between thyroid autoantibodies and miscarriage and preterm birth: meta-analysis of evidence | BMJ: British Medical Journal | 2011 | 439 |
| 29 | Peripheral Chemoreceptors: Function and Plasticity of the Carotid Body | | 2012 | 421 |
| 30 | Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria–specific CD4 + T cells | Science | 2015 | 421 |
| 31 | NDM Metallo-β-Lactamases and Their Bacterial Producers in Health Care Settings | Clinical Microbiology Reviews | 2019 | 406 |
| 32 | Cytokine function in medication-naive first episode psychosis: A systematic review and meta-analysis | Schizophrenia Research | 2014 | 405 |
| 33 | Progress in dimethacrylate-based dental composite technology and curing efficiency | Dental Materials | 2013 | 401 |
| 34 | Recommendations for the standardization of light transmission aggregometry: a consensus of the working party from the platelet physiology subcommittee of SSC/ISTH | Journal of Thrombosis and Haemostasis | 2013 | 398 |
| 35 | Effects and moderators of exercise on quality of life and physical function in patients with cancer: An individual patient data meta-analysis of 34 RCTs | Cancer Treatment Reviews | 2017 | 398 |
| 36 | Factors associated with damage accrual in patients with systemic lupus erythematosus: results from the Systemic Lupus International Collaborating Clinics (SLICC) Inception Cohort | Annals of the Rheumatic Diseases | 2015 | 391 |
| 37 | Clinical and molecular diagnosis, screening and management of Beckwith–Wiedemann syndrome: an international consensus statement | Nature Reviews Endocrinology | 2018 | 388 |
| 38 | Metabolically Healthy Obese and Incident Cardiovascular Disease Events Among 3.5 Million Men and Women | Journal of the American College of Cardiology | 2017 | 383 |
| 39 | Periodontitis in systemic rheumatic diseases | Nature Reviews Rheumatology | 2009 | 380 |
| 40 | The frequency and outcome of lupus nephritis: results from an international inception cohort study | Rheumatology | 2016 | 370 |
| 41 | The crisis of no new antibiotics—what is the way forward? | Lancet Infectious Diseases, The | 2012 | 368 |
| 42 | EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis | Annals of the Rheumatic Diseases | 2012 | 354 |
| 43 | Early mortality in systemic vasculitis: relative contribution of adverse events and active vasculitis | Annals of the Rheumatic Diseases | 2010 | 344 |
| 44 | Systematic review of stepped wedge cluster randomized trials shows that design is particularly used to evaluate interventions during routine implementation | Journal of Clinical Epidemiology | 2011 | 340 |
| 45 | Mortality in Patients with Pituitary Disease | Endocrine Reviews | 2010 | 331 |
| 46 | Prevalence and Relative Risk of Other Autoimmune Diseases in Subjects with Autoimmune Thyroid Disease | American Journal of Medicine | 2010 | 331 |
| 47 | Endothelial dysfunction in COVID-19: a position paper of the ESC Working Group for Atherosclerosis and Vascular Biology, and the ESC Council of Basic Cardiovascular Science | Cardiovascular Research | 2020 | 331 |
| 48 | Lactate modulation of immune responses in inflammatory versus tumour microenvironments | Nature Reviews Immunology | 2021 | 330 |
| 49 | Strength of association between umbilical cord pH and perinatal and long term outcomes: systematic review and meta-analysis | BMJ: British Medical Journal | 2010 | 328 |
| 50 | Why prokaryotes have pangenomes | Nature Microbiology | 2017 | 327 |
