# | Title | Journal | Year | Citations |
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1 | Crystal structure of the outer membrane protease OmpT from Escherichia coli suggests a novel catalytic site | EMBO Journal | 2001 | 242 |
2 | Structural evidence for dimerization-regulated activation of an integral membrane phospholipase | Nature | 1999 | 210 |
3 | Structural evidence for dimerization-regulated activation of an integral membrane phospholipase | Nature | 1999 | 162 |
4 | Structural basis of the chiral selectivity of Pseudomonas cepacia lipase | FEBS Journal | 1998 | 128 |
5 | Outer-membrane phospholipase A: known structure, unknown biological function | Molecular Microbiology | 2000 | 122 |
6 | Cloning, expression, purification and characterization of patatin, a novel phospholipase A | FEBS Journal | 2001 | 116 |
7 | Structural Elements of Secretory Phospholipases A2 Involved in the Binding to M-type Receptors | Journal of Biological Chemistry | 1995 | 114 |
8 | In vitro folding, purification and characterization of Escherichia coli outer membrane protease OmpT | FEBS Journal | 2000 | 99 |
9 | Substrate Specificity of the Integral Membrane Protease OmpT Determined by Spatially Addressed Peptide Libraries† | Biochemistry | 2001 | 94 |
10 | In Vitro Folding of Escherichia Coli Outer-Membrane Phospholipase A | FEBS Journal | 1995 | 90 |
11 | Cutinase from Fusarium solani pisi Hydrolyzing Triglyceride Analogs. Effect of Acyl Chain Length and Position in the Substrate Molecule on Activity and Enantioselectivity | Biochemistry | 1995 | 82 |
12 | Staphylococcal lipases: molecular characterisation, secretion, and processing | Chemistry and Physics of Lipids | 1998 | 82 |
13 | The Lipase from Staphylococcus aureus. Expression in Escherichia coli, Large-scale Purification and Comparison of Substrate Specificity to Staphylococcus hyicus Lipase | FEBS Journal | 1996 | 79 |
14 | NMR structures of phospholipase A2 reveal conformational changes during interfacial activation | Nature Structural and Molecular Biology | 1995 | 72 |
15 | Lipopolysaccharide regions involved in the activation of Escherichia coli outer membrane protease OmpT | FEBS Journal | 2002 | 72 |
16 | Dimerization Regulates the Enzymatic Activity of Escherichia coli Outer Membrane Phospholipase A | Journal of Biological Chemistry | 1997 | 70 |
17 | Cloning, purification and characterisation of the lipase from Staphylococcus epidermidis . Comparison of the substrate selectivity with those of other microbial lipases | FEBS Journal | 1998 | 67 |
18 | Identification of a Calcium Binding Site inStaphylococcus hyicusLipase: Generation of Calcium-Independent Variants† | Biochemistry | 1999 | 66 |
19 | Biochemical and biophysical characterization of in vitro folded outer membrane porin PorA of Neisseria meningitidis | Biochimica Et Biophysica Acta - Biomembranes | 2000 | 55 |
20 | Effect of chemical modification on the activity of lipases in organic solvents | Enzyme and Microbial Technology | 1999 | 49 |
21 | Biochemical properties of staphylococcal (phospho)lipases | Chemistry and Physics of Lipids | 1998 | 46 |
22 | Identification of essential acidic residues of outer membrane protease OmpT supports a novel active site | FEBS Letters | 2001 | 46 |
23 | Incorporation of an unnatural amino acid in the active site of porcine pancreatic phospholipase A2. Substitution of histidine by l,2,4-triazole-3-alanine yields an enzyme with high activity at acidic pH | Protein Engineering, Design and Selection | 1996 | 38 |
24 | The Anticoagulant Effect of the Human Secretory Phospholipase A2 on Blood Plasma and on a Cell-Free System is Due to a Phospholipid-Independent Mechanism of Action Involving the Inhibition of Factor Va | FEBS Journal | 1996 | 37 |
25 | The Suzuki cross-coupling reaction: a powerful tool for the attachment of organometallic ‘NCN’-pincer units to biological scaffolds | Journal of Organometallic Chemistry | 2003 | 37 |
26 | Dissecting the Catalytic Mechanism of Staphylococcal Lipases Using Carbamate Substrates: Chain Length Selectivity, Interfacial Activation, and Cofactor Dependence† | Biochemistry | 1997 | 36 |
27 | Activity and stability of chemically modified Candida antarctica lipase B adsorbed on solid supports | Applied Microbiology and Biotechnology | 1999 | 36 |
28 | Identification of active site serine and histidine residues inEscherichia coliouter membrane protease OmpT | FEBS Letters | 2000 | 34 |
29 | Inactivation of Escherichia coli outer-membrane phospholipase A by the affinity label hexadecanesulfonyl fluoride. Evidence for an active-site serine | FEBS Journal | 1991 | 33 |
30 | Bacteriocin Release Protein Triggers Dimerization of Outer Membrane Phospholipase A In Vivo | Journal of Bacteriology | 1999 | 32 |
31 | Cloning, purification and characterisation of Staphylococcus warneri lipase 2 | BBA - Proteins and Proteomics | 2001 | 30 |
32 | Escherichia coli Outer Membrane Phospholipase A: Role of Two Serines in Enzymatic Activity | Biochemistry | 1996 | 28 |
33 | Directed evolution: From a staphylococcal lipase to a phospholipase | European Journal of Lipid Science and Technology | 2000 | 28 |
34 | Purification and characterization of a mutant human platelet phospholipase A2 expressed in Escherichia coli. Cleavage of a fusion protein with cyanogen bromide | FEBS Journal | 1992 | 27 |
35 | Action of cutinase at the triolein-water interface. Characterisation of interfacial effects during lipid hydrolysis using the oil-drop tensiometer as a tool to study lipase kinetics | Chemistry and Physics of Lipids | 1996 | 27 |
36 | Role of the Cofactor Calcium in the Activation of Outer Membrane Phospholipase A† | Biochemistry | 1998 | 26 |
37 | Substrate Specificity ofStaphylococcus hyicusLipase andStaphylococcus aureusLipase As Studied by in Vivo Chimeragenesis† | Biochemistry | 1998 | 26 |
38 | The phospholipase activity of Staphylococcus hyicus lipase strongly depends on a single Ser to Val mutation | Chemistry and Physics of Lipids | 1998 | 25 |
39 | Unusual Catalytic Triad of Escherichia coli Outer Membrane Phospholipase A | Biochemistry | 2000 | 25 |
40 | The importance of glycine-30 for enzymatic activity of phospholipase A2 | BBA - Proteins and Proteomics | 1991 | 24 |
41 | Enzymatic properties of rat group IIA and V phospholipases A2 compared | Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids | 1999 | 24 |
42 | A Conserved Histidine Residue of Escherichia Coli Outer-Membrane Phospholipase A is Important for Activity | FEBS Journal | 1995 | 22 |
43 | Outer Membrane Phospholipase A Is Dimeric in Phospholipid Bilayers: A Cross-Linking and Fluorescence Resonance Energy Transfer Study | Biochemistry | 1999 | 21 |
44 | Inactivation of Staphylococcus hyicus lipase by hexadecylsulfonyl fluoride: evidence for an active site serine | Protein Engineering, Design and Selection | 1994 | 18 |
45 | Modifying the Substrate Specificity of Staphylococcal Lipases† | Biochemistry | 1999 | 18 |
46 | Crystallization and preliminary X-ray analysis of outer membrane phospholipase A from Escherichia coli | FEBS Letters | 1995 | 15 |
47 | Chiral preference of cutinase in the reaction with phosphonate inhibitors | Biochemical Society Transactions | 1997 | 14 |
48 | The use of genetic engineering to obtain efficient production of porcine pancreatic phospholipase A2 by Saccharomyces cerevisiae | Biochimica Et Biophysica Acta Gene Regulatory Mechanisms | 1991 | 13 |
49 | Structural investigations of the active-site mutant Asn156Ala of outer membrane phospholipase A: Function of the Asn-His interaction in the catalytic triad | Protein Science | 2001 | 13 |
50 | Rational Design of α-Keto Triglyceride Analogues as Inhibitors forStaphylococcus hyicusLipase†,‡ | Biochemistry | 1999 | 12 |