Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase | Nature | 2005 | 3.5K |
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions | Nature | 2005 | 1.7K |
The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair | Nature Cell Biology | 2005 | 516 |
Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage | Molecular and Cellular Biology | 2005 | 439 |
Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1 | Nature | 2005 | 348 |
Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks | Molecular and Cellular Biology | 2005 | 276 |
Methyl methanesulfonate (MMS) produces heat-labile DNA damage but no detectable in vivo DNA double-strand breaks | Nucleic Acids Research | 2005 | 249 |
16S rRNA gene-based identification of midgut bacteria from field-caught Anopheles gambiae sensu lato and A. funestus mosquitoes reveals new species related to known insect symbionts | Applied and Environmental Microbiology | 2005 | 158 |
Poly(ADP-ribose) polymerase (PARP-1) in homologous recombination and as a target for cancer therapy | Cell Cycle | 2005 | 143 |
Extracellular 8-oxo-dG as a sensitive parameter for oxidative stress in vivo and in vitro | Free Radical Research | 2005 | 96 |
Ligand-induced dimerization of Drosophila peptidoglycan recognition proteins in vitro | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 84 |
Radiation tolerance in the eutardigrade Richtersius coronifer | International Journal of Radiation Biology | 2005 | 82 |
Microwaves from GSM mobile telephones affect 53BP1 and gamma-H2AX foci in human lymphocytes from hypersensitive and healthy persons | Environmental Health Perspectives | 2005 | 82 |
915 MHz microwaves and 50 Hz magnetic field affect chromatin conformation and 53BP1 foci in human lymphocytes from hypersensitive and healthy persons | Bioelectromagnetics | 2005 | 65 |
Does early EBV infection protect against IgE sensitization? | Journal of Allergy and Clinical Immunology | 2005 | 60 |
20-Hydroxyecdysone indirectly regulates Hemolin gene expression in Hyalophora cecropia | Insect Molecular Biology | 2005 | 38 |
Dose-response for radiation-induced apoptosis, residual 53BP1 foci and DNA-loop relaxation in human lymphocytes | International Journal of Radiation Biology | 2005 | 35 |
The YrdC protein--a putative ribosome maturation factor | Biochimica Et Biophysica Acta Gene Regulatory Mechanisms | 2005 | 33 |
Abortive translation caused by peptidyl-tRNA drop-off at NGG codons in the early coding region of mRNA | FEBS Journal | 2005 | 32 |
Studies on radiation-induced apoptosis in G0 human lymphocytes | International Journal of Radiation Biology | 2005 | 26 |
Cloning, expression and phylogenetic analysis of Hemolin, from the Chinese oak silkmoth, Antheraea pernyi | Developmental and Comparative Immunology | 2005 | 23 |
Cooperative interactions between bacteriophage P2 integrase and its accessory factors IHF and Cox | Virology | 2005 | 23 |
Reaction-kinetic parameters of glycidamide as determinants of mutagenic potency | Mutation Research - Genetic Toxicology and Environmental Mutagenesis | 2005 | 15 |
Mutagenicity and DNA repair of glycidamide-induced adducts in mammalian cells | Mutation Research - Genetic Toxicology and Environmental Mutagenesis | 2005 | 15 |
Influence of chromatin structure and radical scavengers on yields of radiation-induced 8-oxo-dG and DNA strand breaks in cellular model systems | Radiation Research | 2005 | 12 |