456
Articles
38.4K
Citations
4.2
avg. Impact Factor
84
h-index

Most Cited Articles of Department of Genetics

TitleJournalYearCitations
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymeraseNature20053.5K
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesionsNature20051.7K
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpointsNature20061.5K
Peptide antibiotics and their role in innate immunityAnnual Review of Immunology19951.4K
DNA repair pathways as targets for cancer therapyNature Reviews Cancer20081.2K
Sequence and specificity of two antibacterial proteins involved in insect immunityNature19811.1K
Insect immunity. Purification and properties of three inducible bactericidal proteins from hemolymph of immunized pupae of Hyalophora cecropiaFEBS Journal1980711
Long-term impacts of antibiotic exposure on the human intestinal microbiotaMicrobiology (United Kingdom)2010685
Cell-free immunity in insectsAnnual Review of Microbiology1987651
RNA interference in Lepidoptera: an overview of successful and unsuccessful studies and implications for experimental designJournal of Insect Physiology2011588
Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repairMolecular Cell2010569
Antibacterial peptides: key components needed in immunityCell1991525
The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repairNature Cell Biology2005516
The underlying mechanism for the PARP and BRCA synthetic lethality: clearing up the misunderstandingsMolecular Oncology2011492
DNA double-strand break repair: from mechanistic understanding to cancer treatmentDNA Repair2007478
Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakageMolecular and Cellular Biology2005439
FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testisProceedings of the National Academy of Sciences of the United States of America1995434
A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogasterProceedings of the National Academy of Sciences of the United States of America2000427
PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombinationEMBO Journal2009426
The human gene FALL39 and processing of the cathelin precursor to the antibacterial peptide LL-37 in granulocytesFEBS Journal1996414
Mechanisms of action on Escherichia coli of cecropin P1 and PR-39, two antibacterial peptides from pig intestineInfection and Immunity1993383
A peptidoglycan recognition protein in innate immunity conserved from insects to humansProceedings of the National Academy of Sciences of the United States of America1998378
Antibacterial peptides from pig intestine: isolation of a mammalian cecropinProceedings of the National Academy of Sciences of the United States of America1989370
miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitorsMolecular Cell2011355
Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1Nature2005348