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Top Articles

#TitleJournalYearCitations
1Pharmacology of cardiac potassium channelsCardiovascular Research2004398
2Mutations in the cardiac L-type calcium channel associated with inherited J-wave syndromes and sudden cardiac deathHeart Rhythm2010387
3Antihypertensive effects of the flavonoid quercetin in spontaneously hypertensive ratsBritish Journal of Pharmacology2001381
4Functional Effects of KCNE3 Mutation and Its Role in the Development of Brugada SyndromeCirculation: Arrhythmia and Electrophysiology2008291
5Glucocorticoid receptor gene (NR3C1) methylation processes as mediators of early adversity in stress-related disorders causality: A critical reviewNeuroscience and Biobehavioral Reviews2015262
6A Neutrophil Timer Coordinates Immune Defense and Vascular ProtectionImmunity2019258
7Terpene Compounds in Nature: A Review of Their Potential Antioxidant ActivityCurrent Medicinal Chemistry2012250
8Antihypertensive effects of the flavonoid quercetinPharmacological Reports2009243
9Beneficial effects of polyphenols on cardiovascular diseasePharmacological Research2013230
10The spectrum of congenital anomalies of the VATER association: An international studyAmerican Journal of Medical Genetics Part A1997226
11Experimental rat models to study the metabolic syndromeBritish Journal of Nutrition2009217
12Gender differences in the effects of cardiovascular drugsEuropean Heart Journal - Cardiovascular Pharmacotherapy2017204
13The Role of the Microbial Metabolites Including Tryptophan Catabolites and Short Chain Fatty Acids in the Pathophysiology of Immune-Inflammatory and Neuroimmune DiseaseMolecular Neurobiology2017191
14EUNIS Habitat Classification: Expert system, characteristic species combinations and distribution maps of European habitatsApplied Vegetation Science2020186
15Vasodilator effects of quercetin in isolated rat vascular smooth muscleEuropean Journal of Pharmacology1993185
16Sideritis spp.: Uses, chemical composition and pharmacological activities—A reviewJournal of Ethnopharmacology2011182
17Oxidative Stress and Inflammation in First-Episode Psychosis: A Systematic Review and Meta-analysisSchizophrenia Bulletin2019172
18Endothelium-Independent Vasodilator Effects of the Flavonoid Quercetin and Its Methylated Metabolites in Rat Conductance and Resistance ArteriesJournal of Pharmacology and Experimental Therapeutics2002170
19Endothelial function and cardiovascular disease: Effects of quercetin and wine polyphenolsFree Radical Research2006170
20Serotonin Inhibits Voltage-Gated K + Currents in Pulmonary Artery Smooth Muscle CellsCirculation Research2006170
21Stress-Induced Neuroinflammation: Role of the Toll-Like Receptor-4 PathwayBiological Psychiatry2013169
22Epicatechin lowers blood pressure, restores endothelial function, and decreases oxidative stress and endothelin-1 and NADPH oxidase activity in DOCA-salt hypertensionFree Radical Biology and Medicine2012154
23In Humans, Chronic Atrial Fibrillation Decreases the Transient Outward Current and Ultrarapid Component of the Delayed Rectifier Current Differentially on Each Atria and Increases the Slow Component of the Delayed Rectifier Current in BothJournal of the American College of Cardiology2010152
24New insights into the pharmacology of sodium channel blockersEuropean Heart Journal1992148
25Antiarrhythmic drugs–clinical use and clinical decision making: a consensus document from the European Heart Rhythm Association (EHRA) and European Society of Cardiology (ESC) Working Group on Cardiovascular Pharmacology, endorsed by the Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS) and International Society of Cardiovascular Pharmacotherapy (ISCP)Europace2018144
26Thromboxane A 2 -Induced Inhibition of Voltage-Gated K + Channels and Pulmonary VasoconstrictionCirculation Research2003140
27Twenty-five years in the making: flecainide is safe and effective for the management of atrial fibrillationEuropace2011140
28Compromised Arterial Function in Human Type 2 Diabetic PatientsDiabetes2005136
29Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depressionJournal of Neuroinflammation2011134
30Antihypertensive Peptides Derived from Egg ProteinsJournal of Nutrition2006133
31Gender differences in the effect of cardiovascular drugs: a position document of the Working Group on Pharmacology and Drug Therapy of the ESC: Figure 1European Heart Journal2015131
32Innate immune receptor Toll-like receptor 4 signalling in neuropsychiatric diseasesNeuroscience and Biobehavioral Reviews2016126
33Novel therapeutic targets for the treatment of heart failureNature Reviews Drug Discovery2011125
34Quercetin inhibits vascular superoxide production induced by endothelin-1: Role of NADPH oxidase, uncoupled eNOS and PKCAtherosclerosis2009122
35Anandamide decreases naloxone-precipitated withdrawal signs in mice chronically treated with morphineNeuropharmacology1995116
36Neuronal and inducible nitric oxide synthase and nitrotyrosine immunoreactivities in the cerebral cortex of the aging rat1998115
37Dietary fiber and blood pressure controlFood and Function2016113
38Vascular deconjugation of quercetin glucuronide: The flavonoid paradox revealed?Molecular Nutrition and Food Research2011110
39Toxicokinetics of permethrin in the ratToxicology and Applied Pharmacology1991109
40Cardiovascular safety of non-aspirin non-steroidal anti-inflammatory drugs: review and position paper by the working group for Cardiovascular Pharmacotherapy of the European Society of CardiologyEuropean Heart Journal2016109
41Glucuronidated and sulfated metabolites of the flavonoid quercetin prevent endothelial dysfunction but lack direct vasorelaxant effects in rat aortaAtherosclerosis2009108
42Glucuronidated Quercetin Lowers Blood Pressure in Spontaneously Hypertensive Rats via DeconjugationPLoS ONE2012104
43Drug-Induced Torsade de Pointes. From Molecular Biology to Bedside.The Japanese Journal of Pharmacology2000102
44Quercetin and Isorhamnetin Prevent Endothelial Dysfunction, Superoxide Production, and Overexpression of p47phox Induced by Angiotensin II in Rat AortaJournal of Nutrition200798
45Snail1 Is a Transcriptional Effector of FGFR3 Signaling during Chondrogenesis and AchondroplasiasDevelopmental Cell200797
46Regulatory Role of Cannabinoid Receptor 1 in Stress-Induced Excitotoxicity and NeuroinflammationNeuropsychopharmacology201197
47The flavonoid paradox: conjugation and deconjugation as key steps for the biological activity of flavonoidsJournal of the Science of Food and Agriculture201297
48Neuroprotective and Neurological Properties of Melissa officinalisNeurochemical Research200995
49Activation of neutral sphingomyelinase is involved in acute hypoxic pulmonary vasoconstrictionCardiovascular Research200894
50Antihypertensive Effects of ProbioticsCurrent Hypertension Reports201793