| # | Title | Journal | Year | Citations |
|---|
| 1 | How mental health care should change as a consequence of the COVID-19 pandemic | Lancet Psychiatry,the | 2020 | 1,101 |
| 2 | Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder | Bipolar Disorders | 2018 | 1,079 |
| 3 | The HCL-32: Towards a self-assessment tool for hypomanic symptoms in outpatients | Journal of Affective Disorders | 2005 | 593 |
| 4 | Bipolar disorders | Lancet, The | 2020 | 419 |
| 5 | The World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Biological Treatment of Bipolar Disorders: Update 2012 on the long-term treatment of bipolar disorder | World Journal of Biological Psychiatry | 2013 | 344 |
| 6 | The World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Biological Treatment of Bipolar Disorders: Update 2010 on the treatment of acute bipolar depression | World Journal of Biological Psychiatry | 2010 | 322 |
| 7 | Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study | Lancet, The | 2016 | 306 |
| 8 | The World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Biological Treatment of Bipolar Disorders: Update 2009 on the Treatment of Acute Mania | World Journal of Biological Psychiatry | 2009 | 302 |
| 9 | Safety, tolerability, and risks associated with first- and second-generation antipsychotics: a state-of-the-art clinical review | Therapeutics and Clinical Risk Management | 2017 | 286 |
| 10 | Peripheral brain-derived neurotrophic factor (BDNF) as a biomarker in bipolar disorder: a meta-analysis of 52 studies | BMC Medicine | 2015 | 233 |
| 11 | A systematic literature review of resting state network—functional MRI in bipolar disorder | Journal of Affective Disorders | 2013 | 226 |
| 12 | Assessment and management of agitation in psychiatry: Expert consensus | World Journal of Biological Psychiatry | 2016 | 204 |
| 13 | Effect of cariprazine across the symptoms of mania in bipolar I disorder: Analyses of pooled data from phase II/III trials | European Neuropsychopharmacology | 2015 | 184 |
| 14 | Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder | Human Molecular Genetics | 2016 | 182 |
| 15 | Staging systems in bipolar disorder: an International Society for Bipolar Disorders Task Force Report | Acta Psychiatrica Scandinavica | 2014 | 175 |
| 16 | Cognitive dysfunction in bipolar disorder and schizophrenia: a systematic review of meta-analyses | Neuropsychiatric Disease and Treatment | 2015 | 175 |
| 17 | Long-term safety and tolerability of cariprazine as adjunctive therapy in major depressive disorder | International Clinical Psychopharmacology | 2019 | 170 |
| 18 | Antidepressant Efficacy and Tolerability of Ketamine and Esketamine: A Critical Review | CNS Drugs | 2018 | 167 |
| 19 | Staging in bipolar disorder: from theoretical framework to clinical utility | World Psychiatry | 2017 | 160 |
| 20 | Stratified medicine for mental disorders | European Neuropsychopharmacology | 2014 | 152 |
| 21 | Efficacy of prospective pharmacogenetic testing in the treatment of major depressive disorder: results of a randomized, double-blind clinical trial | BMC Psychiatry | 2017 | 148 |
| 22 | Methodological Recommendations for Trials of Psychological Interventions | Psychotherapy and Psychosomatics | 2018 | 146 |
| 23 | Association of Antidepressant Use With Adverse Health Outcomes | JAMA Psychiatry | 2019 | 143 |
| 24 | New treatment guidelines for acute bipolar depression: A systematic review | Journal of Affective Disorders | 2011 | 135 |
| 25 | The kynurenine pathway in major depressive disorder, bipolar disorder, and schizophrenia: a meta-analysis of 101 studies | Molecular Psychiatry | 2021 | 135 |
| 26 | The identification, assessment and management of difficult-to-treat depression: An international consensus statement | Journal of Affective Disorders | 2020 | 133 |
| 27 | Depressive disorders and suicide: Epidemiology, risk factors, and burden | Neuroscience and Biobehavioral Reviews | 2013 | 131 |
| 28 | The World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Biological Treatment of Bipolar Disorders: Acute and long-term treatment of mixed states in bipolar disorder | World Journal of Biological Psychiatry | 2018 | 128 |
| 29 | SAMP8 mice as a neuropathological model of accelerated brain aging and dementia: Toshio Takeda's legacy and future directions | Neuropathology | 2017 | 127 |
| 30 | Real-world Effectiveness of Pharmacologic Treatments for the Prevention of Rehospitalization in a Finnish Nationwide Cohort of Patients With Bipolar Disorder | JAMA Psychiatry | 2018 | 116 |
| 31 | Enhancing medication adherence in patients with bipolar disorder | Human Psychopharmacology | 2010 | 115 |
| 32 | Food addiction: Prevalence, psychopathological correlates and associations with quality of life in a large sample | Journal of Psychiatric Research | 2018 | 115 |
| 33 | Cannabis and First-Episode Psychosis: Different Long-term Outcomes Depending on Continued or Discontinued Use | Schizophrenia Bulletin | 2011 | 112 |
| 34 | Psychoeducation in bipolar disorder with a SIMPLe smartphone application: Feasibility, acceptability and satisfaction | Journal of Affective Disorders | 2016 | 110 |
| 35 | Risk factors and peripheral biomarkers for schizophrenia spectrum disorders: an umbrella review of meta‐analyses | Acta Psychiatrica Scandinavica | 2018 | 106 |
| 36 | Valproate for the treatment of acute bipolar depression: Systematic review and meta-analysis | Journal of Affective Disorders | 2010 | 102 |
| 37 | Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder | JAMA Psychiatry | 2018 | 102 |
| 38 | Evidence-based umbrella review of 162 peripheral biomarkers for major mental disorders | Translational Psychiatry | 2020 | 102 |
| 39 | Staging Bipolar Disorder | Neurotoxicity Research | 2011 | 100 |
| 40 | Resilience and mental health during the COVID-19 pandemic | Journal of Affective Disorders | 2021 | 98 |
| 41 | Guidelines for the recognition and management of mixed depression | CNS Spectrums | 2017 | 97 |
| 42 | Discriminating cognitive status in Parkinson’s disease through functional connectomics and machine learning | Scientific Reports | 2017 | 88 |
| 43 | Duration of untreated illness as a key to early intervention in schizophrenia: A review | Neuroscience Letters | 2018 | 87 |
| 44 | Internet-based psychological interventions for bipolar disorder: Review of the present and insights into the future | Journal of Affective Disorders | 2015 | 85 |
| 45 | A Double-Blind, Randomized, Placebo-Controlled, Prophylaxis Study of Adjunctive Gabapentin for Bipolar Disorder | Journal of Clinical Psychiatry | 2006 | 83 |
| 46 | Peripheral levels of C-reactive protein, tumor necrosis factor-α, interleukin-6, and interleukin-1β across the mood spectrum in bipolar disorder: A meta-analysis of mean differences and variability | Brain, Behavior, and Immunity | 2021 | 80 |
| 47 | Spanish version of the Screen for Cognitive Impairment in Psychiatry (SCIP-S): Psychometric properties of a brief scale for cognitive evaluation in schizophrenia | Schizophrenia Research | 2008 | 78 |
| 48 | Psychoeducation for bipolar II disorder: An exploratory, 5-year outcome subanalysis | Journal of Affective Disorders | 2009 | 78 |
| 49 | Neurocognitive impairment and psychosocial functioning in bipolar II disorder | Acta Psychiatrica Scandinavica | 2012 | 78 |
| 50 | Bipolar depressed patients show both failure to activate and failure to de-activate during performance of a working memory task | Journal of Affective Disorders | 2013 | 77 |
