| # | Title | Journal | Year | Citations |
|---|
| 1 | Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study | Lancet Oncology, The | 2011 | 3,758 |
| 2 | Image-guided Tumor Ablation: Standardization of Terminology and Reporting Criteria—A 10-Year Update | Radiology | 2014 | 870 |
| 3 | MYC/BCL2 protein coexpression contributes to the inferior survival of activated B-cell subtype of diffuse large B-cell lymphoma and demonstrates high-risk gene expression signatures: a report from The International DLBCL Rituximab-CHOP Consortium Program | Blood | 2013 | 596 |
| 4 | Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 498 |
| 5 | Glioblastoma multiforme: a review of where we have been and where we are going | Expert Opinion on Investigational Drugs | 2009 | 432 |
| 6 | Vandetanib plus docetaxel versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer (ZODIAC): a double-blind, randomised, phase 3 trial | Lancet Oncology, The | 2010 | 407 |
| 7 | Final overall survival results from a randomised, phase III study of erlotinib versus chemotherapy as first-line treatment of EGFR mutation-positive advanced non-small-cell lung cancer (OPTIMAL, CTONG-0802) | Annals of Oncology | 2015 | 406 |
| 8 | Randomized Double-Blind Factorial Trial of Three Treatments To Reduce the Prevalence of Precancerous Gastric Lesions | Journal of the National Cancer Institute | 2006 | 397 |
| 9 | Image-Guided Tumor Ablation: Standardization of Terminology and Reporting Criteria—A 10-Year Update | Journal of Vascular and Interventional Radiology | 2014 | 365 |
| 10 | Magnetic/Upconversion Fluorescent NaGdF4:Yb,Er Nanoparticle-Based Dual-Modal Molecular Probes for Imaging Tiny Tumors in Vivo | ACS Nano | 2013 | 336 |
| 11 | Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents | Gut | 2020 | 232 |
| 12 | Phase II study of sunitinib as second-line treatment for advanced gastric cancer | Investigational New Drugs | 2011 | 179 |
| 13 | Differences in gastric cancer survival between the U.S. and China | Journal of Surgical Oncology | 2015 | 142 |
| 14 | Loss of 5-hydroxymethylcytosine is linked to gene body hypermethylation in kidney cancer | Cell Research | 2016 | 129 |
| 15 | Efficacy of Cranberry Juice on Helicobacter pylori Infection: a Double-Blind, Randomized Placebo-Controlled Trial | Helicobacter | 2005 | 119 |
| 16 | Quality of life (QoL) analyses from OPTIMAL (CTONG-0802), a phase III, randomised, open-label study of first-line erlotinib versus chemotherapy in patients with advanced EGFR mutation-positive non-small-cell lung cancer (NSCLC) | Annals of Oncology | 2013 | 112 |
| 17 | Human Papillomavirus 16 E6 Oncoprotein Interferences with Insulin Signaling Pathway by Binding to Tuberin | Journal of Biological Chemistry | 2004 | 101 |
| 18 | Surgical outcomes from the phase 3 CheckMate 816 trial: Nivolumab (NIVO) + platinum-doublet chemotherapy (chemo) vs chemo alone as neoadjuvant treatment for patients with resectable non-small cell lung cancer (NSCLC). | Journal of Clinical Oncology | 2021 | 99 |
| 19 | L-Asparaginase—Based Regimen in the Treatment of Refractory Midline Nasal/Nasal-Type T/NK-Cell Lymphoma | International Journal of Hematology | 2003 | 96 |
| 20 | The association of the expression level of protein tyrosine phosphatase PRL-3 protein with liver metastasis and prognosis of patients with colorectal cancer | Journal of Cancer Research and Clinical Oncology | 2004 | 88 |
| 21 | MiR-29a Inhibits Cell Proliferation and Induces Cell Cycle Arrest through the Downregulation of p42.3 in Human Gastric Cancer | PLoS ONE | 2011 | 88 |
| 22 | Human papillomavirus type 16 is an important infectious factor in the high incidence of esophageal cancer in Anyang area of China | Carcinogenesis | 2001 | 85 |
| 23 | The Role of Contrast-Enhanced Sonography of Focal Liver Lesions Before Percutaneous Biopsy | American Journal of Roentgenology | 2006 | 84 |
| 24 | Evaluation of Primary Malignancies of the Liver Using Contrast-Enhanced Sonography: Correlation With Pathology | American Journal of Roentgenology | 2006 | 79 |
| 25 | p53 codon 72 polymorphism (C/G) and the risk of human papillomavirus-associated carcinomas in China | Cancer | 2002 | 77 |
| 26 | LMP7/TAP2 gene polymorphisms and HPV infection in esophageal carcinoma patients from a high incidence area in China | Carcinogenesis | 2005 | 75 |
| 27 | Abstract CT003: Nivolumab (NIVO) + platinum-doublet chemotherapy (chemo) vs chemo as neoadjuvant treatment (tx) for resectable (IB-IIIA) non-small cell lung cancer (NSCLC) in the phase 3 CheckMate 816 trial | Cancer Research | 2021 | 74 |
| 28 | Diagnosis of gastric cancer using decision tree classification of mass spectral data | Cancer Science | 2007 | 73 |
| 29 | Methylation of p16 CpG Islands Associated with Malignant Transformation of Gastric Dysplasia in a Population-Based Study | Clinical Cancer Research | 2004 | 72 |
| 30 | CTHRC1 is upregulated by promoter demethylation and transforming growth factor‐β1 and may be associated with metastasis in human gastric cancer | Cancer Science | 2012 | 70 |
| 31 | Cancer stem cell marker CD133+ tumour cells and clinical outcome in rectal cancer | Histopathology | 2009 | 69 |
| 32 | Role of COX-2 in carcinogenesis of colorectal cancer and its relationship with tumor biological characteristics and patients’ prognosis | World Journal of Gastroenterology | 2003 | 67 |
| 33 | Expression of programmed cell death 5 gene involves in regulation of apoptosis in gastric tumor cells | Apoptosis: an International Journal on Programmed Cell Death | 2006 | 66 |
| 34 | Simultaneous detection of CpG methylation and single nucleotide polymorphism by denaturing high performance liquid chromatography | Nucleic Acids Research | 2002 | 63 |
| 35 | Detection of human papillomavirus-16 in ovarian malignancy | British Journal of Cancer | 2003 | 62 |
| 36 | Using diffusion-weighted MR imaging for tumor detection in the collapsed lung: a preliminary study | European Radiology | 2009 | 61 |
| 37 | Methylation of CpG islands of p16 associated with progression of primary gastric carcinomas | Laboratory Investigation | 2006 | 60 |
| 38 | E3 ubiquitin ligase E6AP‐mediated TSC2 turnover in the presence and absence of HPV16 E6 | Genes To Cells | 2008 | 60 |
| 39 | No Impact of Repeated Endoscopic Screens on Gastric Cancer Mortality in a Prospectively Followed Chinese Population at High Risk | Preventive Medicine | 2002 | 58 |
| 40 | iASPP is over-expressed in human non-small cell lung cancer and regulates the proliferation of lung cancer cells through a p53 associated pathway | BMC Cancer | 2010 | 58 |
| 41 | Expression of Cdx2 and Hepatocyte Antigen in Gastric Carcinoma: Correlation with Histologic Type and Implications for Prognosis | Clinical Cancer Research | 2005 | 55 |
| 42 | A Serum Proteomic Pattern for the Detection of Colorectal Adenocarcinoma Using Surface Enhanced Laser Desorption and Ionization Mass Spectrometry | Cancer Investigation | 2006 | 55 |
| 43 | Midline NK/T-cell lymphoma nasal-type: treatment outcome, the effect ofL-asparaginase based regimen, and prognostic factors | Hematological Oncology | 2006 | 54 |
| 44 | Methylation ofGATA-4andGATA-5and development of sporadic gastric carcinomas | World Journal of Gastroenterology | 2010 | 54 |
| 45 | Gastrokine 1 induces senescence through p16/Rb pathway activation in gastric cancer cells | Gut | 2012 | 54 |
| 46 | Breaking bad news in China – the dilemma of patients' autonomy and traditional norms. A first communication skills training for Chinese oncologists and caretakers | Psycho-Oncology | 2013 | 54 |
| 47 | Matrix metalloproteinase 11 depletion inhibits cell proliferation in gastric cancer cells | Biochemical and Biophysical Research Communications | 2005 | 49 |
| 48 | Clinical Implications of Microsatellite Instability and MLH1 Gene Inactivation in Sporadic Insulinomas | Journal of Clinical Endocrinology and Metabolism | 2009 | 48 |
| 49 | Focal Liver Lesions | Investigative Radiology | 2007 | 47 |
| 50 | Association of Cytotoxic T Lymphocyte-associated antigen-4 gene haplotype with the susceptibility to gastric cancer | Molecular Biology Reports | 2010 | 47 |
