# | Title | Journal | Year | Citations |
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1 | Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation | Journal of Immunology | 2010 | 820 |
2 | CATs and HATs: the SLC7 family of amino acid transporters | Pflugers Archiv European Journal of Physiology | 2004 | 587 |
3 | Alternatively activated microglia and macrophages in the central nervous system | Progress in Neurobiology | 2015 | 561 |
4 | Presynaptic Control of Striatal Glutamatergic Neurotransmission by Adenosine A1-A2A Receptor Heteromers | Journal of Neuroscience | 2006 | 553 |
5 | The SLC3 and SLC7 families of amino acid transporters | Molecular Aspects of Medicine | 2013 | 516 |
6 | Coaggregation, Cointernalization, and Codesensitization of Adenosine A2A Receptors and Dopamine D2Receptors | Journal of Biological Chemistry | 2002 | 450 |
7 | Dopamine D1 and adenosine A1 receptors form functionally interacting heteromeric complexes | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 419 |
8 | Adenosine A2A-Dopamine D2 Receptor-Receptor Heteromerization | Journal of Biological Chemistry | 2003 | 401 |
9 | p16Ink4a overexpression in cancer: a tumor suppressor gene associated with senescence and high-grade tumors | Oncogene | 2011 | 375 |
10 | Evidence for a Mitochondrial Regulatory Pathway Defined by Peroxisome Proliferator-Activated Receptor- Coactivator-1 , Estrogen-Related Receptor- , and Mitofusin 2 | Diabetes | 2006 | 320 |
11 | Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase: a control enzyme in ketogenesis | Biochemical Journal | 1999 | 319 |
12 | Targeting cell cycle regulation in cancer therapy | Biochemical Journal | 2013 | 284 |
13 | Metabolic control analysis in drug discovery and disease | Nature Biotechnology | 2002 | 270 |
14 | Detection of heteromerization of more than two proteins by sequential BRET-FRET | Nature Methods | 2008 | 269 |
15 | Molecular and cellular mechanisms of skeletal muscle atrophy: an update | Journal of Cachexia, Sarcopenia and Muscle | 2012 | 264 |
16 | Cancer-associated malnutrition | European Journal of Oncology Nursing | 2005 | 242 |
17 | Adenosine receptor–dopamine receptor interactions in the basal ganglia and their relevance for brain function | Physiology and Behavior | 2007 | 239 |
18 | TrkB and TrkC Signaling Are Required for Maturation and Synaptogenesis of Hippocampal Connections | Journal of Neuroscience | 1998 | 230 |
19 | CD26, adenosine deaminase, and adenosine receptors mediate costimulatory signals in the immunological synapse | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 229 |
20 | Striatal Adenosine A2A and Cannabinoid CB1 Receptors Form Functional Heteromeric Complexes that Mediate the Motor Effects of Cannabinoids | Neuropsychopharmacology | 2007 | 229 |
21 | Identification of LAT4, a Novel Amino Acid Transporter with System L Activity | Journal of Biological Chemistry | 2005 | 216 |
22 | Hypoxia Promotes Glycogen Accumulation through Hypoxia Inducible Factor (HIF)-Mediated Induction of Glycogen Synthase 1 | PLoS ONE | 2010 | 209 |
23 | Adenosine A2A and Dopamine D2 Heteromeric Receptor Complexes and Their Function | Journal of Molecular Neuroscience | 2005 | 207 |
24 | Cannabinoid Receptors CB1 and CB2 Form Functional Heteromers in Brain | Journal of Biological Chemistry | 2012 | 196 |
25 | Combining Mass Spectrometry and Pull-Down Techniques for the Study of Receptor Heteromerization. Direct Epitope−Epitope Electrostatic Interactions between Adenosine A2Aand Dopamine D2Receptors | Analytical Chemistry | 2004 | 195 |
26 | Human adenosine deaminase 2 induces differentiation of monocytes into macrophages and stimulates proliferation of T helper cells and macrophages | Journal of Leukocyte Biology | 2010 | 192 |
27 | Targeting nanoparticles to CD40, DEC-205 or CD11c molecules on dendritic cells for efficient CD8+ T cell response: A comparative study | Journal of Controlled Release | 2014 | 187 |
28 | Overexpression of Interleukin-15 Induces Skeletal Muscle Hypertrophy in Vitro: Implications for Treatment of Muscle Wasting Disorders | Experimental Cell Research | 2002 | 186 |
29 | Mechanisms of cannabidiol neuroprotection in hypoxic–ischemic newborn pigs: Role of 5HT1A and CB2 receptors | Neuropharmacology | 2013 | 182 |
30 | Maslinic acid, a natural triterpene from Olea europaea L., induces apoptosis in HT29 human colon-cancer cells via the mitochondrial apoptotic pathway | Cancer Letters | 2009 | 177 |
31 | TNF-α Represses β-Klotho Expression and Impairs FGF21 Action in Adipose Cells: Involvement of JNK1 in the FGF21 Pathway | Endocrinology | 2012 | 176 |
32 | Mitochondrial Fatty Acid Oxidation in Obesity | Antioxidants and Redox Signaling | 2013 | 175 |
33 | Oleate prevents saturated-fatty-acid-induced ER stress, inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism | Diabetologia | 2013 | 173 |
34 | The role of amino acid transporters in inherited and acquired diseases | Biochemical Journal | 2011 | 172 |
35 | Aspects of the general biology of adenosine A2A signaling | Progress in Neurobiology | 2007 | 168 |
36 | Gleevec (STI571) Influences Metabolic Enzyme Activities and Glucose Carbon Flow toward Nucleic Acid and Fatty Acid Synthesis in Myeloid Tumor Cells | Journal of Biological Chemistry | 2001 | 166 |
37 | Oxythiamine and dehydroepiandrosterone induce a G1phase cycle arrest in Ehrlich's tumor cells through inhibition of the pentose cycle | FEBS Letters | 1999 | 164 |
38 | PPARs in the Control of Uncoupling Proteins Gene Expression | PPAR Research | 2007 | 163 |
39 | Thiazolidinediones and Rexinoids Induce Peroxisome Proliferator-Activated Receptor-Coactivator (PGC)-1α Gene Transcription: An Autoregulatory Loop Controls PGC-1α Expression in Adipocytes via Peroxisome Proliferator-Activated Receptor-γ Coactivation | Endocrinology | 2006 | 160 |
40 | Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors | PLoS Biology | 2015 | 157 |
41 | Glycogen accumulation underlies neurodegeneration and autophagy impairment in Lafora disease | Human Molecular Genetics | 2014 | 155 |
42 | Direct involvement of σ-1 receptors in the dopamine D 1 receptor-mediated effects of cocaine | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 153 |
43 | The effect of thiamine supplementation on tumour proliferation | FEBS Journal | 2001 | 152 |
44 | Activators of peroxisome proliferator-activated receptor-alpha induce the expression of the uncoupling protein-3 gene in skeletal muscle: a potential mechanism for the lipid intake-dependent activation of uncoupling protein-3 gene expression at birth | Diabetes | 1999 | 148 |
45 | Interleukin-15 stimulates adiponectin secretion by 3T3-L1 adipocytes: Evidence for a skeletal muscle-to-fat signaling pathway | Cell Biology International | 2005 | 148 |
46 | Role of glutamate on T-cell mediated immunity | Journal of Neuroimmunology | 2007 | 148 |
47 | Evidence for Adenosine/Dopamine Receptor Interactions Indications for Heteromerization | Neuropsychopharmacology | 2000 | 147 |
48 | Antioxidant and Pro-oxidant Effect of the Thiolic Compounds N -acetyl- l -cysteine and Glutathione against Free Radical-induced Lipid Peroxidation | Free Radical Research | 2002 | 141 |
49 | Loss of hepatic chaperone‐mediated autophagy accelerates proteostasis failure in aging | Aging Cell | 2015 | 141 |
50 | Adenosine A2A receptor stimulation potentiates nitric oxide release by activated microglia | Journal of Neurochemistry | 2005 | 140 |