| # | Title | Journal | Year | Citations |
|---|
| 1 | Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial | Lancet, The | 2002 | 2,333 |
| 2 | Ciclosporin versus infliximab in patients with severe ulcerative colitis refractory to intravenous steroids: a parallel, open-label randomised controlled trial | Lancet, The | 2012 | 517 |
| 3 | Accuracy of Revised Bethesda Guidelines, Microsatellite Instability, and Immunohistochemistry for the Identification of Patients With Hereditary Nonpolyposis Colorectal Cancer | JAMA - Journal of the American Medical Association | 2005 | 457 |
| 4 | Identification of Lynch Syndrome Among Patients With Colorectal Cancer | JAMA - Journal of the American Medical Association | 2012 | 443 |
| 5 | Preoperative Staging and Tumor Resectability Assessment of Pancreatic Cancer: Prospective Study Comparing Endoscopic Ultrasonography, Helical Computed Tomography, Magnetic Resonance Imaging, and Angiography | American Journal of Gastroenterology | 2004 | 398 |
| 6 | ESGE and ESGENA Position Statement on gastrointestinal endoscopy and the COVID-19 pandemic | Endoscopy | 2020 | 324 |
| 7 | Long-term results of the European achalasia trial: a multicentre randomised controlled trial comparing pneumatic dilation versus laparoscopic Heller myotomy | Gut | 2016 | 321 |
| 8 | Short-term outcome analysis of a randomized study comparing laparoscopic vs open colectomy for colon cancer | Surgical Endoscopy and Other Interventional Techniques | 1995 | 310 |
| 9 | Transanal Total Mesorectal Excision for Rectal Cancer: Outcomes after 140 Patients | Journal of the American College of Surgeons | 2015 | 292 |
| 10 | Serous cystic neoplasm of the pancreas: a multinational study of 2622 patients under the auspices of the International Association of Pancreatology and European Pancreatic Club (European Study Group on Cystic Tumors of the Pancreas) | Gut | 2016 | 274 |
| 11 | Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 240 |
| 12 | A multicenter, randomized, clinical trial of hormonal therapy in the prevention of rebleeding from gastrointestinal angiodysplasia | Gastroenterology | 2001 | 225 |
| 13 | Port site metastases and recurrence after laparoscopic colectomy | Surgical Endoscopy and Other Interventional Techniques | 1998 | 223 |
| 14 | Characterization of Inflammation and Fibrosis in Crohn’s Disease Lesions by Magnetic Resonance Imaging | American Journal of Gastroenterology | 2015 | 215 |
| 15 | Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer | PLoS Genetics | 2011 | 188 |
| 16 | The efficacy of adjuvant chemotherapy with 5-fluorouracil in colorectal cancer depends on the mismatch repair status | European Journal of Cancer | 2009 | 179 |
| 17 | VCAM-1, but Not ICAM-1 or MAdCAM-1, Immunoblockade Ameliorates DSS-Induced Colitis in Mice | Laboratory Investigation | 2000 | 172 |
| 18 | Comparison between universal molecular screening for Lynch syndrome and revised Bethesda guidelines in a large population-based cohort of patients with colorectal cancer | Gut | 2012 | 172 |
| 19 | Liver dysfunction related to hepatitis B and C in patients with inflammatory bowel disease treated with immunosuppressive therapy | Gut | 2010 | 168 |
| 20 | A High Degree of LINE-1 Hypomethylation Is a Unique Feature of Early-Onset Colorectal Cancer | PLoS ONE | 2012 | 164 |
| 21 | THE IMPACT OF DONOR AGE ON LIVER TRANSPLANTATION: INFLUENCE OF DONOR AGE ON EARLY LIVER FUNCTION AND ON SUBSEQUENT PATIENT AND GRAFT SURVIVAL | Transplantation | 2001 | 146 |
| 22 | Superoxide dismutase ameliorates TNBS-induced colitis by reducing oxidative stress, adhesion molecule expression, and leukocyte recruitment into the inflamed intestine | Journal of Leukocyte Biology | 2004 | 141 |
| 23 | Detection of BRAF V600E Mutation in Colorectal Cancer | Journal of Molecular Diagnostics | 2006 | 136 |
| 24 | Familial risk-colorectal cancer: ESMO Clinical Practice Guidelines | Annals of Oncology | 2013 | 136 |
| 25 | Curcumin Modulates DNA Methylation in Colorectal Cancer Cells | PLoS ONE | 2013 | 135 |
| 26 | Postoperative complications of laparoscopic-assisted colectomy | Surgical Endoscopy and Other Interventional Techniques | 1997 | 125 |
| 27 | European guidelines on microscopic colitis: United European Gastroenterology and European Microscopic Colitis Group statements and recommendations | United European Gastroenterology Journal | 2021 | 122 |
| 28 | Long-term outcome of patients with steroid-refractory acute severe UC treated with ciclosporin or infliximab | Gut | 2018 | 119 |
| 29 | Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42 103 individuals | Gut | 2013 | 117 |
| 30 | The transcription factor GATA6 enables self-renewal of colon adenoma stem cells by repressing BMP gene expression | Nature Cell Biology | 2014 | 115 |
| 31 | Spectrum of gluten-sensitive enteropathy in first-degree relatives of patients with coeliac disease: clinical relevance of lymphocytic enteritis | Gut | 2006 | 104 |
| 32 | Platelet activation In mice and human Helicobacter pylori infection. | Journal of Clinical Investigation | 1997 | 103 |
| 33 | Secondary bacterial peritonitis in cirrhosis: A retrospective study of clinical and analytical characteristics, diagnosis and management | Journal of Hepatology | 2010 | 100 |
| 34 | Value of postoperative surveillance after radical surgery for colorectal cancer | Diseases of the Colon and Rectum | 1998 | 99 |
| 35 | Clinical management of hereditary colorectal cancer syndromes | Nature Reviews Gastroenterology and Hepatology | 2015 | 99 |
| 36 | Endoscopic Ultrasound–guided Fine-needle Biopsy With or Without Rapid On-site Evaluation for Diagnosis of Solid Pancreatic Lesions: A Randomized Controlled Non-Inferiority Trial | Gastroenterology | 2021 | 99 |
| 37 | Intestinal spirochetosis and chronic watery diarrhea: Clinical and histological response to treatment and long-term follow up | Journal of Gastroenterology and Hepatology (Australia) | 2006 | 94 |
| 38 | Detection of colonic cells in peripheral blood of colorectal cancer patients by means of reverse transcriptase and polymerase chain reaction | British Journal of Cancer | 1998 | 91 |
| 39 | EUS and magnetic resonance imaging in the staging of rectal cancer: a prospective and comparative study | Gastrointestinal Endoscopy | 2011 | 90 |
| 40 | A Prospective, Multicenter, Population-Based Study of BRAF Mutational Analysis for Lynch Syndrome Screening | Clinical Gastroenterology and Hepatology | 2008 | 85 |
| 41 | Recurrence and virulence of colonic diverticulitis in immunocompromised patients | American Journal of Surgery | 2012 | 81 |
| 42 | Paucicellular Lymphocytic Colitis: Is It a Minor Form of Lymphocytic Colitis? A Clinical Pathological and Immunological Study | American Journal of Gastroenterology | 2009 | 79 |
| 43 | Relative roles of ICAM-1 and VCAM-1 in the pathogenesis of experimental radiation-induced intestinal inflammation | International Journal of Radiation Oncology Biology Physics | 2003 | 76 |
| 44 | Differential Expression of cdc25 Cell-Cycle–Activating Phosphatases in Human Colorectal Carcinoma | Laboratory Investigation | 2001 | 74 |
| 45 | Cytokine and endothelial cell adhesion molecule expression in interleukin-10-deficient mice | American Journal of Physiology - Renal Physiology | 2000 | 72 |
| 46 | Frequency of hereditary non-polyposis colorectal cancer and other colorectal cancer familial forms in Spain | European Journal of Gastroenterology and Hepatology | 2004 | 72 |
| 47 | The European Panel on the Appropriateness of Gastrointestinal Endoscopy guidelines colonoscopy in an open-access endoscopy unit: a prospective study | Alimentary Pharmacology and Therapeutics | 2005 | 71 |
| 48 | Lack of prognostic influence of circulating tumor cells in peripheral blood of patients with colorectal cancer | Gastroenterology | 2001 | 70 |
| 49 | Hydrocolonic Sonography for Evaluating Inflammatory Bowel Disease | American Journal of Roentgenology | 2001 | 70 |
| 50 | The prevalence of coeliac disease is significantly higher in children compared with adults | Alimentary Pharmacology and Therapeutics | 2011 | 70 |
