| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 2 | Kinase-targeted cancer therapies: progress, challenges and future directions | Molecular Cancer | 2018 | 796 |
| 3 | Metal-Based Nanoparticles as Antimicrobial Agents: An Overview | Nanomaterials | 2020 | 769 |
| 4 | Improved screening procedure for biogenic amine production by lactic acid bacteria | International Journal of Food Microbiology | 1999 | 626 |
| 5 | Structure, Bioactivity and Synthesis of Natural Products with Hexahydropyrrolo[2,3‐b]indole | Chemistry - A European Journal | 2011 | 429 |
| 6 | Effect of resveratrol, a natural polyphenolic compound, on reactive oxygen species and prostaglandin production | Biochemical Pharmacology | 2000 | 362 |
| 7 | Gamma-aminobutyric acid as a bioactive compound in foods: a review | Journal of Functional Foods | 2014 | 353 |
| 8 | Recent developments in the chemistry of dihydropyridines | Journal of the Chemical Society, Perkin Transactions 1 | 2002 | 339 |
| 9 | Synthesis of Strychnine | Chemical Reviews | 2000 | 302 |
| 10 | Oleate Reverses Palmitate-induced Insulin Resistance and Inflammation in Skeletal Muscle Cells | Journal of Biological Chemistry | 2008 | 285 |
| 11 | Wastewater treatment and water reuse | Current Opinion in Environmental Science and Health | 2018 | 276 |
| 12 | Biological effects of oxysterols: Current status | Food and Chemical Toxicology | 1996 | 271 |
| 13 | Olive oil intake and risk of cardiovascular disease and mortality in the PREDIMED Study | BMC Medicine | 2014 | 267 |
| 14 | Red wine polyphenols modulate fecal microbiota and reduce markers of the metabolic syndrome in obese patients | Food and Function | 2016 | 262 |
| 15 | Amino acid-decarboxylase activity of bacteria isolated from fermented pork sausages | International Journal of Food Microbiology | 2001 | 252 |
| 16 | β-Sitosterol modulates antioxidant enzyme response in RAW 264.7 macrophages | Free Radical Biology and Medicine | 2005 | 239 |
| 17 | New peptide architectures through C–H activation stapling between tryptophan–phenylalanine/tyrosine residues | Nature Communications | 2015 | 235 |
| 18 | Preparation, characterization and biocompatibility studies on risperidone-loaded solid lipid nanoparticles (SLN): High pressure homogenization versus ultrasound | Colloids and Surfaces B: Biointerfaces | 2011 | 222 |
| 19 | (Eco)toxicity and biodegradability of selected protic and aprotic ionic liquids | Journal of Hazardous Materials | 2013 | 209 |
| 20 | Rapid changes in histone deacetylases and inflammatory gene expression in expert meditators | Psychoneuroendocrinology | 2014 | 209 |
| 21 | Premature Delivery Influences the Immunological Composition of Colostrum and Transitional and Mature Human Milk | Journal of Nutrition | 2011 | 203 |
| 22 | Current Research Therapeutic Strategies for Alzheimer’s Disease Treatment | Neural Plasticity | 2016 | 200 |
| 23 | Effect of olive oil minor components on oxidative stress and arachidonic acid mobilization and metabolism by macrophages RAW 264.7 | Free Radical Biology and Medicine | 2003 | 197 |
| 24 | Nanomedicines for ocular NSAIDs: safety on drug delivery | Nanomedicine: Nanotechnology, Biology, and Medicine | 2009 | 196 |
| 25 | Gender differences in then-3 fatty acid content of tissues | Proceedings of the Nutrition Society | 2008 | 193 |
| 26 | Epicatechin, procyanidins, and phenolic microbial metabolites after cocoa intake in humans and rats | Analytical and Bioanalytical Chemistry | 2009 | 192 |
| 27 | Chiral Oxazolopiperidone Lactams: Versatile Intermediates for the Enantioselective Synthesis of Piperidine-Containing Natural Products | Chemistry - A European Journal | 2006 | 186 |
| 28 | Determination of hydroperoxides in foods and biological samples by the ferrous oxidation–xylenol orange method: A review of the factors that influence the method’s performance | Analytical Biochemistry | 2008 | 179 |
| 29 | Biorational insecticides in pest management | Journal of Pesticide Sciences | 2008 | 178 |
| 30 | Oleate prevents saturated-fatty-acid-induced ER stress, inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism | Diabetologia | 2013 | 173 |
| 31 | Evaluation of scavenging activity assessed by Co(II)/EDTA-induced luminol chemiluminescence and DPPH· (2,2-diphenyl-1-picrylhydrazyl) free radical assay | Journal of Pharmacological and Toxicological Methods | 2000 | 172 |
| 32 | On the Performance of Continuum Solvation Methods. A Comment on “Universal Approaches to Solvation Modeling” | Accounts of Chemical Research | 2009 | 171 |
| 33 | Strawberry Polyphenols Attenuate Ethanol-Induced Gastric Lesions in Rats by Activation of Antioxidant Enzymes and Attenuation of MDA Increase | PLoS ONE | 2011 | 166 |
| 34 | The p65 subunit of NF-κB binds to PGC-1α, linking inflammation and metabolic disturbances in cardiac cells | Cardiovascular Research | 2010 | 164 |
| 35 | The degree of unsaturation of dietary fatty acids and the development of atherosclerosis (review) | Journal of Nutritional Biochemistry | 2003 | 163 |
| 36 | Memantine loaded PLGA PEGylated nanoparticles for Alzheimer’s disease: in vitro and in vivo characterization | Journal of Nanobiotechnology | 2018 | 163 |
| 37 | Optimization and physicochemical characterization of a triamcinolone acetonide-loaded NLC for ocular antiangiogenic applications | International Journal of Pharmaceutics | 2010 | 160 |
| 38 | Polyphenols and Health: Current State and Progress | Journal of Agricultural and Food Chemistry | 2012 | 159 |
| 39 | Design and ocular tolerance of flurbiprofen loaded ultrasound-engineered NLC | Colloids and Surfaces B: Biointerfaces | 2010 | 156 |
| 40 | Palmitate Induces Tumor Necrosis Factor-α Expression in C2C12 Skeletal Muscle Cells by a Mechanism Involving Protein Kinase C and Nuclear Factor-κB Activation | Endocrinology | 2006 | 155 |
| 41 | Peroxisome proliferator-activated receptor ?/? activation inhibits hypertrophy in neonatal rat cardiomyocytes | Cardiovascular Research | 2005 | 154 |
| 42 | Enantioselective Synthesis of Piperidine, Indolizidine, and Quinolizidine Alkaloids from a Phenylglycinol-Derived δ-Lactam | Journal of Organic Chemistry | 2003 | 147 |
| 43 | TNF-α reduces PGC-1α expression through NF-κB and p38 MAPK leading to increased glucose oxidation in a human cardiac cell model | Cardiovascular Research | 2009 | 147 |
| 44 | Current Applications of Nanoemulsions in Cancer Therapeutics | Nanomaterials | 2019 | 147 |
| 45 | Genetic Analysis of a Chromosomal Region Containing Genes Required for Assimilation of Allantoin Nitrogen and Linked Glyoxylate Metabolism in Escherichia coli | Journal of Bacteriology | 1999 | 143 |
| 46 | Polyamines under Abiotic Stress: Metabolic Crossroads and Hormonal Crosstalks in Plants | Metabolites | 2012 | 142 |
| 47 | FADS1 FADS2 gene variants modify the association between fish intake and the docosahexaenoic acid proportions in human milk | American Journal of Clinical Nutrition | 2010 | 141 |
| 48 | Nanostructured lipid carriers for triamcinolone acetonide delivery to the posterior segment of the eye | Colloids and Surfaces B: Biointerfaces | 2011 | 139 |
| 49 | In vitro immunomodulatory activity of Lactobacillus fermentum CECT5716 and Lactobacillus salivarius CECT5713: two probiotic strains isolated from human breast milk | Immunobiology | 2010 | 138 |
| 50 | New aspects of the role of hydroxyeicosatetraenoic acids in cell growth and cancer development | Biochemical Pharmacology | 2009 | 136 |
