| # | Title | Journal | Year | Citations |
|---|
| 1 | Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study | Lancet, The | 2007 | 2,527 |
| 2 | Glycine receptor antibodies in PERM and related syndromes: characteristics, clinical features and outcomes | Brain | 2014 | 430 |
| 3 | Multivariable Analysis of Outcome Predictors and Adjustment of Main Outcome Results to Baseline Data Profile in Randomized Controlled Trials | Stroke | 2008 | 397 |
| 4 | Immunological aspects of grafting in the mammalian central nervous system. A review and speculative synthesis | Brain Research Reviews | 1988 | 342 |
| 5 | Autoreactive T lymphocytes in multiple sclerosis determined by antigen-induced secretion of interferon-gamma. | Journal of Clinical Investigation | 1990 | 337 |
| 6 | Stroke treatment with alteplase given 3·0–4·5 h after onset of acute ischaemic stroke (ECASS III): additional outcomes and subgroup analysis of a randomised controlled trial | Lancet Neurology, The | 2009 | 303 |
| 7 | MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction | Nature Genetics | 2005 | 276 |
| 8 | Implementation and outcome of thrombolysis with alteplase 3–4·5 h after an acute stroke: an updated analysis from SITS-ISTR | Lancet Neurology, The | 2010 | 275 |
| 9 | Autoreactive T and B cells responding to myelin proteolipid protein in multiple sclerosis and controls | European Journal of Immunology | 1991 | 246 |
| 10 | Mortality of Epilepsy in Developed Countries: A Review | Epilepsia | 2005 | 242 |
| 11 | HLA-DR15 is associated with lower age at onset in multiple sclerosis | Annals of Neurology | 2000 | 239 |
| 12 | Do antiepileptic drugs or generalized tonic–clonic seizure frequency increase SUDEP risk? A combined analysis | Epilepsia | 2012 | 224 |
| 13 | T and B cell responses to myelin-oligodendrocyte glycoprotein in multiple sclerosis. | Journal of Immunology | 1991 | 222 |
| 14 | T and B cell responses to myelin-oligodendrocyte glycoprotein in multiple sclerosis | Journal of Immunology | 1991 | 218 |
| 15 | EuroInf: AMulticenter Comparative Observational Study of Apomorphine and Levodopa Infusion in Parkinson's Disease | Movement Disorders | 2015 | 203 |
| 16 | Antibodies to myelin-oligodendrocyte glycoprotein in cerebrospinal fluid from patients with multiple sclerosis and controls | Journal of Neuroimmunology | 1991 | 183 |
| 17 | AN ELECTROMYOGRAPHIC STUDY OF THE NOCICEPTIVE REFLEXES OF THE LOWER LIMB. MECHANISM OF THE PLANTAR RESPONSES | Brain | 1960 | 173 |
| 18 | Genetic variation in the KIF1B locus influences susceptibility to multiple sclerosis | Nature Genetics | 2008 | 173 |
| 19 | Environmental and genetic risk factors for MS: an integrated review | Annals of Clinical and Translational Neurology | 2019 | 165 |
| 20 | Prevalence and predictors of pain and fatigue after stroke: a population-based study | International Journal of Rehabilitation Research | 2006 | 159 |
| 21 | Increased transforming growth factor-β, interleukin-4, and interferon-γ in multiple sclerosis | Annals of Neurology | 1994 | 156 |
| 22 | Carbohydrate-deficient glycoprotein syndromes: Peculiar group of new disorders | Pediatric Neurology | 1993 | 147 |
| 23 | A new type of hereditary distal myopathy with characteristic sarcoplasmic bodies and intermediate (skeletin) filaments | Journal of the Neurological Sciences | 1980 | 145 |
| 24 | Effects of age on enzyme-histochemical fibre spectra and contractile properties of fast- and slow-twitch skeletal muscles in the rat | Journal of the Neurological Sciences | 1986 | 145 |
| 25 | Nonconvulsive Status Epilepticus in Adults: Thirty-Two Consecutive Patients from a General Hospital Population | Epilepsia | 1992 | 145 |
| 26 | Cytokines in neuroinflammatory disease: role of myelin autoreactive T cell production of interferon-gamma | Journal of Neuroimmunology | 1992 | 141 |
| 27 | CD8 is critically involved in lymphocyte activation by a T. brucei brucei-released molecule | Cell | 1993 | 136 |
| 28 | Antimyelin basic protein and antimyelin antibody-producing cells in multiple sclerosis | Annals of Neurology | 1990 | 131 |
| 29 | Genes in the HLA class I region may contribute to the HLA class II-associated genetic susceptibility to multiple sclerosis | Tissue Antigens | 2004 | 130 |
| 30 | IgG production within the central nervous system: A critical review of proposed formulae | Annals of Neurology | 1985 | 124 |
| 31 | Gamma-interferon-like immunoreactivity in axotomized rat motor neurons | Journal of Neuroscience | 1989 | 124 |
| 32 | Increased numbers of T cells recognizing multiple myelin basic protein epitopes in multiple sclerosis | European Journal of Immunology | 1992 | 116 |
| 33 | Functional Outcome in Patients With Lacunar Infarction | Stroke | 1996 | 116 |
| 34 | Interleukin-6 is elevated in plasma in multiple sclerosis | Journal of Neuroimmunology | 1991 | 114 |
| 35 | Neurogenic effects on the palatopharyngeal muscle in patients with obstructive sleep apnoea: a muscle biopsy study. | Journal of Neurology, Neurosurgery and Psychiatry | 1992 | 110 |
| 36 | Suppression of experimental autoimmune myasthenia gravis by oral administration of acetylcholine receptor | Journal of Neuroimmunology | 1993 | 109 |
| 37 | Sensory receptors in ankle joint capsules of normal and arthritic rats | Experimental Brain Research | 1985 | 106 |
| 38 | Bidirectional activating signals betweenTrypanosoma brucei and CD8+ T cells: A trypanosome-released factor triggers interferon-γ production that stimulates parasite growth | European Journal of Immunology | 1991 | 106 |
| 39 | Human leukocyte antigen studies in multiple sclerosis | Annals of Neurology | 1994 | 105 |
| 40 | Acetylcholine receptor-reactive T and B cells in myasthenia gravis and controls. | Journal of Clinical Investigation | 1991 | 104 |
| 41 | γδ+ T cells are increased in patients with Parkinson's disease | Journal of the Neurological Sciences | 1994 | 103 |
| 42 | Absence of seven human herpesviruses, including HHV-6, by polymerase chain reaction in CSF and blood from patients with multiple sclerosis and optic neuritis | Acta Neurologica Scandinavica | 1997 | 101 |
| 43 | EFFECTS OF COMBINED PANCREATIC AND RENAL TRANSPLANTATION ON DIABETIC NEUROPATHY: A TWO-YEAR FOLLOW-UP STUDY | Lancet, The | 1987 | 99 |
| 44 | Behavioral and electrophysiological effects of various types of peripheral nerve lesions in the rat: A comparison of possible models for chronic pain | Pain | 1980 | 97 |
| 45 | Polymorphisms in IL-1β and IL-1 receptor antagonist genes are associated with myasthenia gravis | Journal of Neuroimmunology | 1998 | 91 |
| 46 | Meeting Review: The management of multiple sclerosis in children: a European view | Multiple Sclerosis Journal | 2010 | 91 |
| 47 | B cell alterations during BAFF inhibition with belimumab in SLE | EBioMedicine | 2019 | 88 |
| 48 | A heterozygous 21-bp deletion inCAPN3causes dominantly inherited limb girdle muscular dystrophy | Brain | 2016 | 87 |
| 49 | Hereditary spastic paraplegia type 5: natural history, biomarkers and a randomized controlled trial | Brain | 2017 | 87 |
| 50 | Local enhancement of major histocompatibility complex (MHC) class I and II expression and cell infiltration in experimental allergic encephalomyelitis around axotomized motor neurons | Journal of Neuroimmunology | 1989 | 86 |
