| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 3 | Dynamics of Hippocampal Neurogenesis in Adult Humans | Cell | 2013 | 1,523 |
| 4 | International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study | Lancet, The | 2018 | 1,487 |
| 5 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 6 | Towards the introduction of the ‘Immunoscore’ in the classification of malignant tumours | Journal of Pathology | 2014 | 1,151 |
| 7 | Association analysis identifies 65 new breast cancer risk loci | Nature | 2017 | 1,099 |
| 8 | Allele-specific copy number analysis of tumors | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 979 |
| 9 | The nf-core framework for community-curated bioinformatics pipelines | Nature Biotechnology | 2020 | 963 |
| 10 | Large-scale genotyping identifies 41 new loci associated with breast cancer risk | Nature Genetics | 2013 | 960 |
| 11 | Hallmarks of cancer: Interactions with the tumor stroma | Experimental Cell Research | 2010 | 955 |
| 12 | 4th ESO–ESMO International Consensus Guidelines for Advanced Breast Cancer (ABC 4) | Annals of Oncology | 2018 | 891 |
| 13 | Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas | Acta Neuropathologica | 2012 | 863 |
| 14 | Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 | Cell Death and Differentiation | 2015 | 811 |
| 15 | Neurogenesis in the Striatum of the Adult Human Brain | Cell | 2014 | 786 |
| 16 | Chemoresistance Evolution in Triple-Negative Breast Cancer Delineated by Single-Cell Sequencing | Cell | 2018 | 777 |
| 17 | 5th ESO-ESMO international consensus guidelines for advanced breast cancer (ABC 5) | Annals of Oncology | 2020 | 761 |
| 18 | Cells release subpopulations of exosomes with distinct molecular and biological properties | Scientific Reports | 2016 | 728 |
| 19 | Consensus guidelines for the detection of immunogenic cell death | OncoImmunology | 2014 | 686 |
| 20 | Cancer classification using the Immunoscore: a worldwide task force | Journal of Translational Medicine | 2012 | 676 |
| 21 | Targeting mutant p53 for efficient cancer therapy | Nature Reviews Cancer | 2018 | 655 |
| 22 | mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation | Cell Metabolism | 2013 | 647 |
| 23 | Incidence of human papillomavirus (HPV) positive tonsillar carcinoma in Stockholm, Sweden: An epidemic of viral‐induced carcinoma? | International Journal of Cancer | 2009 | 645 |
| 24 | Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease | Nature Communications | 2018 | 584 |
| 25 | Dabrafenib plus trametinib versus dabrafenib monotherapy in patients with metastatic BRAF V600E/K-mutant melanoma: long-term survival and safety analysis of a phase 3 study | Annals of Oncology | 2017 | 549 |
| 26 | Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer | Nature Genetics | 2015 | 513 |
| 27 | A prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma | Journal of Translational Medicine | 2011 | 500 |
| 28 | Caspase signalling controls microglia activation and neurotoxicity | Nature | 2011 | 491 |
| 29 | Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties | Nanomedicine: Nanotechnology, Biology, and Medicine | 2015 | 487 |
| 30 | Optimal fractionation of preoperative radiotherapy and timing to surgery for rectal cancer (Stockholm III): a multicentre, randomised, non-blinded, phase 3, non-inferiority trial | Lancet Oncology, The | 2017 | 447 |
| 31 | Genome-wide association study identifies three loci associated with melanoma risk | Nature Genetics | 2009 | 422 |
| 32 | Comprehensive Proteomic Analysis of Mesenchymal Stem Cell Exosomes Reveals Modulation of Angiogenesis via Nuclear Factor-KappaB Signaling | Stem Cells | 2016 | 407 |
| 33 | mTOR coordinates protein synthesis, mitochondrial activity and proliferation | Cell Cycle | 2015 | 397 |
| 34 | Human papillomavirus as a risk factor for the increase in incidence of tonsillar cancer | International Journal of Cancer | 2006 | 396 |
| 35 | Overview of the 2022 WHO Classification of Thyroid Neoplasms | Endocrine Pathology | 2022 | 388 |
| 36 | Genome-wide association studies identify four ER negative–specific breast cancer risk loci | Nature Genetics | 2013 | 374 |
| 37 | p53 suppresses the self-renewal of adult neural stem cells | Development (Cambridge) | 2006 | 373 |
| 38 | Ibrutinib combined with bendamustine and rituximab compared with placebo, bendamustine, and rituximab for previously treated chronic lymphocytic leukaemia or small lymphocytic lymphoma (HELIOS): a randomised, double-blind, phase 3 study | Lancet Oncology, The | 2016 | 373 |
| 39 | Cancer-Associated Fibroblasts as Another Polarized Cell Type of the Tumor Microenvironment | Frontiers in Oncology | 2014 | 363 |
| 40 | Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair | Nature Genetics | 2015 | 357 |
| 41 | The Age of Olfactory Bulb Neurons in Humans | Neuron | 2012 | 333 |
| 42 | What is the restriction point? | Current Opinion in Cell Biology | 1995 | 320 |
| 43 | Quality of life and patient satisfaction in breast cancer patients after immediate breast reconstruction: a prospective study | Breast | 2005 | 320 |
| 44 | Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer | Nature Genetics | 2014 | 320 |
| 45 | Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission | EMBO Journal | 2011 | 318 |
| 46 | Shaping Genetic Alterations in Human Cancer: The p53 Mutation Paradigm | Cancer Cell | 2007 | 316 |
| 47 | Prostate cancer screening in men aged 50–69 years (STHLM3): a prospective population-based diagnostic study | Lancet Oncology, The | 2015 | 308 |
| 48 | Combining intensity, edge and shape information for 2D and 3D segmentation of cell nuclei in tissue sections | Journal of Microscopy | 2004 | 293 |
| 49 | 1st International consensus guidelines for advanced breast cancer (ABC 1) | Breast | 2012 | 291 |
| 50 | The mutational landscapes of genetic and chemical models of Kras-driven lung cancer | Nature | 2015 | 285 |
