| # | Title | Journal | Year | Citations |
|---|
| 1 | Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement | Cytotherapy | 2006 | 13,839 |
| 2 | Premature ageing in mice expressing defective mitochondrial DNA polymerase | Nature | 2004 | 2,318 |
| 3 | Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2 | Cell | 2020 | 1,827 |
| 4 | Clarification of the nomenclature for MSC: The International Society for Cellular Therapy position statement | Cytotherapy | 2005 | 1,661 |
| 5 | The gut microbiota influences blood-brain barrier permeability in mice | Science Translational Medicine | 2014 | 1,589 |
| 6 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 7 | Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data | BMJ: British Medical Journal | 2017 | 1,408 |
| 8 | Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials | Lancet, The | 2010 | 1,168 |
| 9 | Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver | Cell | 2015 | 1,166 |
| 10 | Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting | Journal of Extracellular Vesicles | 2015 | 1,077 |
| 11 | Long-term ecological impacts of antibiotic administration on the human intestinal microbiota | ISME Journal | 2007 | 885 |
| 12 | Long-term impacts of antibiotic exposure on the human intestinal microbiota | Microbiology (United Kingdom) | 2010 | 859 |
| 13 | Metabolism and function of coenzyme Q | Biochimica Et Biophysica Acta - Biomembranes | 2004 | 858 |
| 14 | Cells release subpopulations of exosomes with distinct molecular and biological properties | Scientific Reports | 2016 | 728 |
| 15 | Cytomegalovirus Infection Drives Adaptive Epigenetic Diversification of NK Cells with Altered Signaling and Effector Function | Immunity | 2015 | 650 |
| 16 | Extracellular vesicles as drug delivery systems: Why and how? | Advanced Drug Delivery Reviews | 2020 | 606 |
| 17 | Advances in therapeutic applications of extracellular vesicles | Science Translational Medicine | 2019 | 595 |
| 18 | Haploidentical transplant with posttransplant cyclophosphamide vs matched unrelated donor transplant for acute myeloid leukemia | Blood | 2015 | 565 |
| 19 | Global Tuberculosis Report 2020 – Reflections on the Global TB burden, treatment and prevention efforts | International Journal of Infectious Diseases | 2021 | 526 |
| 20 | Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 516 |
| 21 | Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 491 |
| 22 | Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties | Nanomedicine: Nanotechnology, Biology, and Medicine | 2015 | 487 |
| 23 | Metronidazole Is Still the Drug of Choice for Treatment of Anaerobic Infections | Clinical Infectious Diseases | 2010 | 464 |
| 24 | Analysis of Tissues Following Mesenchymal Stromal Cell Therapy in Humans Indicates Limited Long-Term Engraftment and No Ectopic Tissue Formation | Stem Cells | 2012 | 456 |
| 25 | Bruton’s tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain | Immunological Reviews | 2009 | 434 |
| 26 | Strong Purifying Selection in Transmission of Mammalian Mitochondrial DNA | PLoS Biology | 2008 | 425 |
| 27 | Comprehensive Proteomic Analysis of Mesenchymal Stem Cell Exosomes Reveals Modulation of Angiogenesis via Nuclear Factor-KappaB Signaling | Stem Cells | 2016 | 407 |
| 28 | Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine | ACS Nano | 2016 | 397 |
| 29 | A pneumococcal pilus influences virulence and host inflammatory responses | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 395 |
| 30 | Systemic exosomal siRNA delivery reduced alpha-synuclein aggregates in brains of transgenic mice | Movement Disorders | 2014 | 384 |
| 31 | Proteolytic Processing of OPA1 Links Mitochondrial Dysfunction to Alterations in Mitochondrial Morphology | Journal of Biological Chemistry | 2006 | 382 |
| 32 | Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection | Blood | 2013 | 347 |
| 33 | The structures ofEscherichia coliO-polysaccharide antigens | FEMS Microbiology Reviews | 2006 | 346 |
| 34 | Human recombinant soluble ACE2 in severe COVID-19 | Lancet Respiratory Medicine,the | 2020 | 340 |
| 35 | PPARα is a key regulator of hepatic FGF21 | Biochemical and Biophysical Research Communications | 2007 | 337 |
| 36 | Vitamin D and Respiratory Tract Infections: A Systematic Review and Meta-Analysis of Randomized Controlled Trials | PLoS ONE | 2013 | 334 |
| 37 | Same Exposure but Two Radically Different Responses to Antibiotics: Resilience of the Salivary Microbiome versus Long-Term Microbial Shifts in Feces | MBio | 2015 | 333 |
| 38 | Ancestral SARS-CoV-2-specific T cells cross-recognize the Omicron variant | Nature Medicine | 2022 | 333 |
| 39 | Myosin-X provides a motor-based link between integrins and the cytoskeleton | Nature Cell Biology | 2004 | 328 |
| 40 | Epigenetic Regulation of HIV-1 Latency by Cytosine Methylation | PLoS Pathogens | 2009 | 321 |
| 41 | New antituberculosis drugs, regimens, and adjunct therapies: needs, advances, and future prospects | Lancet Infectious Diseases, The | 2014 | 302 |
| 42 | Use of doping agents, particularly anabolic steroids, in sports and society | Lancet, The | 2008 | 297 |
| 43 | Bridging the efficacy–effectiveness gap: a regulator's perspective on addressing variability of drug response | Nature Reviews Drug Discovery | 2011 | 293 |
| 44 | Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome | Journal of Experimental Medicine | 2015 | 293 |
| 45 | Mitochondrial dysfunction as a cause of ageing | Journal of Internal Medicine | 2008 | 292 |
| 46 | Vitamin D supplementation to prevent acute respiratory infections: a systematic review and meta-analysis of aggregate data from randomised controlled trials | Lancet Diabetes and Endocrinology,the | 2021 | 292 |
| 47 | Functional studies of mesenchymal stem cells derived from adult human adipose tissue | Experimental Cell Research | 2005 | 279 |
| 48 | T-bet and Eomes Are Differentially Linked to the Exhausted Phenotype of CD8+ T Cells in HIV Infection | PLoS Pathogens | 2014 | 273 |
| 49 | Defective cytotoxic lymphocyte degranulation in syntaxin-11–deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients | Blood | 2007 | 272 |
| 50 | Immunology of bacterial polysaccharide antigens | Carbohydrate Research | 2003 | 269 |
