| # | Title | Journal | Year | Citations |
|---|
| 1 | The nuclear RNase III Drosha initiates microRNA processing | Nature | 2003 | 4,463 |
| 2 | RNA velocity of single cells | Nature | 2018 | 2,602 |
| 3 | Reactive oxygen species, antioxidants, and the mammalian thioredoxin system1 1This review is based on the licentiate thesis “Thioredoxin reductase—interactions with the redox active compounds 1-chloro-2,4-dinitrobenzene and lipoic acid” by Jonas Nordberg, 2001, Karolinska Institute, Stockholm, ISBN 91-631-1064-4. | Free Radical Biology and Medicine | 2001 | 2,223 |
| 4 | Pericytes regulate the blood–brain barrier | Nature | 2010 | 2,214 |
| 5 | Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises | Developmental Cell | 2011 | 2,123 |
| 6 | Physiological functions of thioredoxin and thioredoxin reductase | FEBS Journal | 2000 | 2,091 |
| 7 | The Human Transcription Factors | Cell | 2018 | 2,048 |
| 8 | Molecular Architecture of the Mouse Nervous System | Cell | 2018 | 2,002 |
| 9 | Visualization and analysis of gene expression in tissue sections by spatial transcriptomics | Science | 2016 | 1,983 |
| 10 | Role of platelet-derived growth factors in physiology and medicine | Genes and Development | 2008 | 1,904 |
| 11 | Endothelial/Pericyte Interactions | Circulation Research | 2005 | 1,748 |
| 12 | Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing | Nature Neuroscience | 2015 | 1,710 |
| 13 | Positionally Cloned Gene for a Novel Glomerular Protein—Nephrin—Is Mutated in Congenital Nephrotic Syndrome | Molecular Cell | 1998 | 1,654 |
| 14 | Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk | Nature Genetics | 2019 | 1,625 |
| 15 | The Human Cell Atlas | ELife | 2017 | 1,547 |
| 16 | Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis | Nature | 2007 | 1,515 |
| 17 | Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay | Science | 2013 | 1,444 |
| 18 | Short-chain dehydrogenases/reductases (SDR) | Biochemistry | 1995 | 1,230 |
| 19 | From Selenium to Selenoproteins: Synthesis, Identity, and Their Role in Human Health | Antioxidants and Redox Signaling | 2007 | 1,089 |
| 20 | Quantitative single-cell RNA-seq with unique molecular identifiers | Nature Methods | 2014 | 1,047 |
| 21 | Apolipoprotein E controls cerebrovascular integrity via cyclophilin A | Nature | 2012 | 1,019 |
| 22 | Single-cell sequencing-based technologies will revolutionize whole-organism science | Nature Reviews Genetics | 2013 | 1,012 |
| 23 | Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death | Cell Metabolism | 2008 | 1,009 |
| 24 | Hallmarks of cancer: Interactions with the tumor stroma | Experimental Cell Research | 2010 | 955 |
| 25 | Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis | Cell | 2018 | 920 |
| 26 | Impact of cytosine methylation on DNA binding specificities of human transcription factors | Science | 2017 | 912 |
| 27 | The cellular thermal shift assay for evaluating drug target interactions in cells | Nature Protocols | 2014 | 900 |
| 28 | Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence | Nature Genetics | 2018 | 893 |
| 29 | CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response | Nature Medicine | 2018 | 874 |
| 30 | Origin, fate and dynamics of macrophages at central nervous system interfaces | Nature Immunology | 2016 | 872 |
| 31 | Counting absolute numbers of molecules using unique molecular identifiers | Nature Methods | 2012 | 869 |
| 32 | Arrest of -Amyloid Fibril Formation by a Pentapeptide Ligand | Journal of Biological Chemistry | 1996 | 850 |
| 33 | Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos | Cell | 2016 | 830 |
| 34 | Characterization of the single-cell transcriptional landscape by highly multiplex RNA-seq | Genome Research | 2011 | 828 |
| 35 | (+)-7-iso-Jasmonoyl-L-isoleucine is the endogenous bioactive jasmonate | Nature Chemical Biology | 2009 | 822 |
| 36 | [21] Thioredoxin and thioredoxin reductase | Methods in Enzymology | 1995 | 812 |
| 37 | Tracking cancer drugs in living cells by thermal profiling of the proteome | Science | 2014 | 812 |
| 38 | Functional receptor for GDNF encoded by the c-ret proto-oncogene | Nature | 1996 | 785 |
| 39 | Endothelial-Mural Cell Signaling in Vascular Development and Angiogenesis | Arteriosclerosis, Thrombosis, and Vascular Biology | 2009 | 784 |
| 40 | Chemoresistance Evolution in Triple-Negative Breast Cancer Delineated by Single-Cell Sequencing | Cell | 2018 | 777 |
| 41 | Small molecule RITA binds to p53, blocks p53–HDM-2 interaction and activates p53 function in tumors | Nature Medicine | 2004 | 746 |
| 42 | Medium- and short-chain dehydrogenase/reductase gene and protein families | Cellular and Molecular Life Sciences | 2008 | 738 |
| 43 | Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines | Nature Medicine | 2014 | 734 |
| 44 | Toward a unified nomenclature for mammalian ADP-ribosyltransferases | Trends in Biochemical Sciences | 2010 | 724 |
| 45 | Activation of the TrkB Neurotrophin Receptor Is Induced by Antidepressant Drugs and Is Required for Antidepressant-Induced Behavioral Effects | Journal of Neuroscience | 2003 | 720 |
| 46 | Mechanisms underlying mutational signatures in human cancers | Nature Reviews Genetics | 2014 | 703 |
| 47 | The Expression of the Gene Coding for the Antibacterial Peptide LL-37 Is Induced in Human Keratinocytes during Inflammatory Disorders | Journal of Biological Chemistry | 1997 | 698 |
| 48 | Replication stress links structural and numerical cancer chromosomal instability | Nature | 2013 | 694 |
| 49 | Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells | Cell | 2016 | 687 |
| 50 | Certain organochlorine and organobromine contaminants in Swedish human milk in perspective of past 20–30 years | Chemosphere | 2000 | 674 |
