# | Title | Journal | Year | Citations |
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1 | Foxp3 programs the development and function of CD4+CD25+ regulatory T cells | Nature Immunology | 2003 | 6,653 |
2 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 | Cell Death and Differentiation | 2018 | 4,036 |
3 | A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17 | Nature Immunology | 2005 | 3,869 |
4 | The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5 | Nature | 2001 | 3,186 |
5 | Toll-like receptors in the induction of the innate immune response | Nature | 2000 | 2,784 |
6 | T cell receptor antagonist peptides induce positive selection | Cell | 1994 | 2,538 |
7 | MECHANISMS OF PHAGOCYTOSIS IN MACROPHAGES | Annual Review of Immunology | 1999 | 2,366 |
8 | Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3 | Immunity | 2005 | 2,070 |
9 | The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 1,823 |
10 | TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function | Nature | 2008 | 1,649 |
11 | A function for interleukin 2 in Foxp3-expressing regulatory T cells | Nature Immunology | 2005 | 1,577 |
12 | Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice | Nature Immunology | 2007 | 1,523 |
13 | Collaborative Induction of Inflammatory Responses by Dectin-1 and Toll-like Receptor 2 | Journal of Experimental Medicine | 2003 | 1,447 |
14 | Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus | Nature Genetics | 2000 | 1,403 |
15 | Regulation of Interferon‐γ During Innate and Adaptive Immune Responses | Advances in Immunology | 2007 | 1,373 |
16 | The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens | Nature | 1999 | 1,295 |
17 | Cd8+ but Not Cd8− Dendritic Cells Cross-Prime Cytotoxic T Cells in Vivo | Journal of Experimental Medicine | 2000 | 1,171 |
18 | A Critical Role for Dnmt1 and DNA Methylation in T Cell Development, Function, and Survival | Immunity | 2001 | 1,124 |
19 | Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help | Science | 2003 | 1,107 |
20 | Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease | Nature Medicine | 2016 | 1,088 |
21 | Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria | Nature Immunology | 2010 | 1,074 |
22 | FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT | Cell | 2006 | 1,019 |
23 | Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate | Nature | 2010 | 1,009 |
24 | Foxp3-dependent programme of regulatory T-cell differentiation | Nature | 2007 | 1,008 |
25 | TGF-β1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells | Journal of Experimental Medicine | 2005 | 918 |
26 | CD4 + Regulatory T Cells Control T H 17 Responses in a Stat3-Dependent Manner | Science | 2009 | 895 |
27 | Autoimmune T cell responses in the central nervous system | Nature Reviews Immunology | 2009 | 849 |
28 | A mechanism for the initiation of allergen-induced T helper type 2 responses | Nature Immunology | 2008 | 837 |
29 | Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection | Journal of Experimental Medicine | 2005 | 813 |
30 | Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 | Cell Death and Differentiation | 2015 | 811 |
31 | Effector and Memory CTL Differentiation | Annual Review of Immunology | 2007 | 776 |
32 | CD8+ T Cells: Foot Soldiers of the Immune System | Immunity | 2011 | 775 |
33 | Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells | Nature | 2007 | 765 |
34 | Selecting and maintaining a diverse T-cell repertoire | Nature | 1999 | 747 |
35 | Massive Expansion of Antigen-Specific CD8+ T Cells during an Acute Virus Infection | Immunity | 1998 | 741 |
36 | Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3 | Nature Immunology | 2007 | 741 |
37 | Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 724 |
38 | Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein | Immunity | 2009 | 716 |
39 | Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 698 |
40 | Regulation of inflammatory responses by IL-17F | Journal of Experimental Medicine | 2008 | 690 |
41 | Necroptosis in development, inflammation and disease | Nature Reviews Molecular Cell Biology | 2017 | 687 |
42 | Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 680 |
43 | Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells | Nature | 2006 | 678 |
44 | Helping the CD8+ T-cell response | Nature Reviews Immunology | 2004 | 673 |
45 | Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism | Nature Immunology | 2001 | 637 |
46 | Recognition of the Peripheral Self by Naturally Arising CD25+ CD4+ T Cell Receptors | Immunity | 2004 | 634 |
47 | Foxp3 in control of the regulatory T cell lineage | Nature Immunology | 2007 | 619 |
48 | Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response | Nature Genetics | 2009 | 610 |
49 | Epigenetic control of T-helper-cell differentiation | Nature Reviews Immunology | 2009 | 600 |
50 | Naive T Cells Transiently Acquire a Memory-like Phenotype during Homeostasis-Driven Proliferation | Journal of Experimental Medicine | 2000 | 591 |