| # | Title | Journal | Year | Citations |
|---|
| 1 | Microbial biogeography: putting microorganisms on the map | Nature Reviews Microbiology | 2006 | 2,434 |
| 2 | DNA Topoisomerases: Structure, Function, and Mechanism | Annual Review of Biochemistry | 2001 | 2,404 |
| 3 | Pyroptosis: host cell death and inflammation | Nature Reviews Microbiology | 2009 | 2,372 |
| 4 | Bacterial competition: surviving and thriving in the microbial jungle | Nature Reviews Microbiology | 2010 | 2,085 |
| 5 | Antimicrobial activity of metals: mechanisms, molecular targets and applications | Nature Reviews Microbiology | 2013 | 1,987 |
| 6 | The genome of the domesticated apple (Malus × domestica Borkh.) | Nature Genetics | 2010 | 1,891 |
| 7 | Into the Eye of the Cytokine Storm | Microbiology and Molecular Biology Reviews | 2012 | 1,557 |
| 8 | Evolutionary and Biomedical Insights from the Rhesus Macaque Genome | Science | 2007 | 1,283 |
| 9 | Aminoglycoside antibiotics induce bacterial biofilm formation | Nature | 2005 | 1,112 |
| 10 | Viruses and interferon: a fight for supremacy | Nature Reviews Immunology | 2002 | 1,078 |
| 11 | Gene expression in Pseudomonas aeruginosa biofilms | Nature | 2001 | 1,037 |
| 12 | Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1β via Ipaf | Nature Immunology | 2006 | 1,022 |
| 13 | General Method for the Isolation of Plasmid Deoxyribonucleic Acid | Journal of Bacteriology | 1973 | 915 |
| 14 | Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus | Nature | 2007 | 892 |
| 15 | Interaction and signalling between a cosmopolitan phytoplankton and associated bacteria | Nature | 2015 | 875 |
| 16 | A Type VI Secretion System of Pseudomonas aeruginosa Targets a Toxin to Bacteria | Cell Host and Microbe | 2010 | 838 |
| 17 | The Genomes of Oryza sativa: A History of Duplications | PLoS Biology | 2005 | 808 |
| 18 | Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA | Nature | 2004 | 784 |
| 19 | Evidence That Hepatitis C Virus Resistance to Interferon Is Mediated through Repression of the PKR Protein Kinase by the Nonstructural 5A Protein | Virology | 1997 | 764 |
| 20 | The Genome of the Natural Genetic Engineer Agrobacterium tumefaciens C58 | Science | 2001 | 741 |
| 21 | A chemosensory system that regulates biofilm formation through modulation of cyclic diguanylate levels | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 734 |
| 22 | From The Cover: Iron and Pseudomonas aeruginosa biofilm formation | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 714 |
| 23 | Salmonellae interplay with host cells | Nature Reviews Microbiology | 2008 | 708 |
| 24 | Revisiting the role of the granuloma in tuberculosis | Nature Reviews Immunology | 2012 | 687 |
| 25 | Type VI secretion system effectors: poisons with a purpose | Nature Reviews Microbiology | 2014 | 681 |
| 26 | Selective Silencing of Foreign DNA with Low GC Content by the H-NS Protein in Salmonella | Science | 2006 | 672 |
| 27 | Agrobacterium tumefaciens DNA and PS8 Bacteriophage DNA Not Detected in Crown Gall Tumors | Proceedings of the National Academy of Sciences of the United States of America | 1974 | 659 |
| 28 | Type VI secretion delivers bacteriolytic effectors to target cells | Nature | 2011 | 643 |
| 29 | Membrane Vesicle Release in Bacteria, Eukaryotes, and Archaea: a Conserved yet Underappreciated Aspect of Microbial Life | Infection and Immunity | 2012 | 622 |
| 30 | Identification of FleQ from Pseudomonas aeruginosa as a c‐di‐GMP‐responsive transcription factor | Molecular Microbiology | 2008 | 606 |
| 31 | Prevalence of hydrogen peroxide-producing Lactobacillus species in normal women and women with bacterial vaginosis | Journal of Clinical Microbiology | 1989 | 594 |
| 32 | Control of PKR Protein Kinase by Hepatitis C Virus Nonstructural 5A Protein: Molecular Mechanisms of Kinase Regulation | Molecular and Cellular Biology | 1998 | 584 |
| 33 | Data access for the 1,000 Plants (1KP) project | GigaScience | 2014 | 582 |
| 34 | Coupling of Flagellar Gene Expression to Flagellar Assembly in Salmonella enterica Serovar Typhimurium and Escherichia coli | Microbiology and Molecular Biology Reviews | 2000 | 579 |
| 35 | Lipid A Acylation and Bacterial Resistance against Vertebrate Antimicrobial Peptides | Cell | 1998 | 569 |
| 36 | Regulation of B-cell fate by antigen-receptor signals | Nature Reviews Immunology | 2002 | 568 |
| 37 | A network of networks: Quorum-sensing gene regulation in Pseudomonas aeruginosa | International Journal of Medical Microbiology | 2006 | 563 |
| 38 | Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase | Science | 1992 | 556 |
| 39 | Human Toll-like receptor 4 recognizes host-specific LPS modifications | Nature Immunology | 2002 | 548 |
| 40 | Bacterial Communities in Women with Bacterial Vaginosis: High Resolution Phylogenetic Analyses Reveal Relationships of Microbiota to Clinical Criteria | PLoS ONE | 2012 | 545 |
| 41 | STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade | Science Translational Medicine | 2015 | 543 |
| 42 | Oral Cancer Risk in Relation to Sexual History and Evidence of Human Papillomavirus Infection | Journal of the National Cancer Institute | 1998 | 527 |
| 43 | Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections | Cell | 2012 | 523 |
| 44 | Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks | Nature Genetics | 2008 | 515 |
| 45 | The superficial life of microbes | Nature | 2006 | 507 |
| 46 | UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators | Developmental Cell | 2008 | 507 |
| 47 | Acyl-Homoserine Lactone Quorum Sensing: From Evolution to Application | Annual Review of Microbiology | 2013 | 504 |
| 48 | The lta4h Locus Modulates Susceptibility to Mycobacterial Infection in Zebrafish and Humans | Cell | 2010 | 501 |
| 49 | TNF Dually Mediates Resistance and Susceptibility to Mycobacteria via Mitochondrial Reactive Oxygen Species | Cell | 2013 | 501 |
| 50 | Pel is a cationic exopolysaccharide that cross-links extracellular DNA in the Pseudomonas aeruginosa biofilm matrix | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 485 |
