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Top Articles

#TitleJournalYearCitations
1N6-methyladenosine-dependent regulation of messenger RNA stabilityNature20143,138
2Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone ModificationCell20111,462
3Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1Autophagy20211,430
4On the road to cancer: aneuploidy and the mitotic checkpointNature Reviews Cancer20051,046
5Centromeres and KinetochoresCell2003926
6Non–cell autonomous toxicity in neurodegenerative disorders: ALS and beyondJournal of Cell Biology2009913
7Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian GenomeCell2012912
8Analysis of the Vertebrate Insulator Protein CTCF-Binding Sites in the Human GenomeCell2007910
9CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter FunctionCell2015846
10TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegenerationHuman Molecular Genetics2010840
11Molecular architecture of the kinetochore–microtubule interfaceNature Reviews Molecular Cell Biology2008798
12Boveri revisited: chromosomal instability, aneuploidy and tumorigenesisNature Reviews Molecular Cell Biology2009745
13Aneuploidy Acts Both Oncogenically and as a Tumor SuppressorCancer Cell2007652
14Sustained Therapeutic Reversal of Huntington's Disease by Transient Repression of Huntingtin SynthesisNeuron2012635
15The 4D nucleome projectNature2017579
16Propagation of centromeric chromatin requires exit from mitosisJournal of Cell Biology2007558
17Next-generation genomics: an integrative approachNature Reviews Genetics2010554
18Rethinking ALS: The FUS about TDP-43Cell2009516
19Cytokinesis in Animal CellsAnnual Review of Cell and Developmental Biology2012497
20Decoding the links between mitosis, cancer, and chemotherapy: The mitotic checkpoint, adaptation, and cell deathCancer Cell2005458
21Rewiring of Genetic Networks in Response to DNA DamageScience2010408
22Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpointProceedings of the National Academy of Sciences of the United States of America2004389
23Reversible centriole depletion with an inhibitor of Polo-like kinase 4Science2015372
24ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43Proceedings of the National Academy of Sciences of the United States of America2013370
25Lysine 2-hydroxyisobutyrylation is a widely distributed active histone markNature Chemical Biology2014368
26PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progressionNature2010367
27The Seeds of Neurodegeneration: Prion-like Spreading in ALSCell2011335
28Genome-wide mapping and analysis of chromosome architectureNature Reviews Molecular Cell Biology2016324
29Progressive degeneration of human neural stem cells caused by pathogenic LRRK2Nature2012312
30Epigenetic Centromere Propagation and the Nature of CENP-A NucleosomesCell2011311
31Protein Architecture of the Human Kinetochore Microtubule Attachment SiteCell2009310
32Understanding the role of TDP-43 and FUS/TLS in ALS and beyondCurrent Opinion in Neurobiology2011308
33Inducible, reversible system for the rapid and complete degradation of proteins in mammalian cellsProceedings of the National Academy of Sciences of the United States of America2012277
34Centriole Assembly Requires Both Centriolar and Pericentriolar Material ProteinsDevelopmental Cell2004273
35Katanin controls mitotic and meiotic spindle lengthJournal of Cell Biology2006266
36Chromosome Mis-segregation Generates Cell-Cycle-Arrested Cells with Complex Karyotypes that Are Eliminated by the Immune SystemDevelopmental Cell2017263
37Misfolded Mutant SOD1 Directly Inhibits VDAC1 Conductance in a Mouse Model of Inherited ALSNeuron2010256
38Cep152 interacts with Plk4 and is required for centriole duplicationJournal of Cell Biology2010255
39Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stabilityJournal of Cell Biology2010251
40Losing balance: the origin and impact of aneuploidy in cancerEMBO Reports2012239
41Tet-assisted bisulfite sequencing of 5-hydroxymethylcytosineNature Protocols2012236
42Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome lossJournal of Cell Biology2003233
43Chromoanagenesis and cancer: mechanisms and consequences of localized, complex chromosomal rearrangementsNature Medicine2012231
44A two-step mechanism for epigenetic specification of centromere identity and functionNature Cell Biology2013226
45Dynamics of Centromere and Kinetochore ProteinsImplications for Checkpoint Signaling and SilencingCurrent Biology2004224
46A complex containing the Sm protein CAR-1 and the RNA helicase CGH-1 is required for embryonic cytokinesis in Caenorhabditis elegansJournal of Cell Biology2005222
47ZW10 links mitotic checkpoint signaling to the structural kinetochoreJournal of Cell Biology2005221
48Finding distal regulatory elements in the human genomeCurrent Opinion in Genetics and Development2009218
49An alternative pluripotent state confers interspecies chimaeric competencyNature2015215
50Fine Tuning of Craniofacial Morphology by Distant-Acting EnhancersScience2013209