| # | Title | Journal | Year | Citations |
|---|
| 1 | Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor | Science | 2000 | 5,486 |
| 2 | Artificial intelligence and deep learning in ophthalmology | British Journal of Ophthalmology | 2019 | 754 |
| 3 | Rhodopsin dimers in native disc membranes | Nature | 2003 | 732 |
| 4 | Molecular Components of the Mammalian Circadian Clock | Handbook of Experimental Pharmacology | 2013 | 544 |
| 5 | Organization of the G Protein-coupled Receptors Rhodopsin and Opsin in Native Membranes | Journal of Biological Chemistry | 2003 | 534 |
| 6 | Discussion | Progress in Retinal and Eye Research | 1998 | 514 |
| 7 | Distribution of cones in human and monkey retina: individual variability and radial asymmetry | Science | 1987 | 512 |
| 8 | The Morphological Development of the Human Fovea | Ophthalmology | 1984 | 472 |
| 9 | Molecular cloning and characterization of retinal photoreceptor guanylyl cyclase-activating protein | Neuron | 1994 | 449 |
| 10 | Morphometric Analysis of Macular Photoreceptors and Ganglion Cells in Retinas With Retinitis Pigmentosa | JAMA Ophthalmology | 1992 | 423 |
| 11 | The neurological organization of pathways between the dorsal lateral geniculate nucleus and visual cortex in old world and new world primates | Journal of Comparative Neurology | 1978 | 398 |
| 12 | Interlaminar connections and pyramidal neuron organisation in the visual cortex, area 17, of the Macaque monkey | Journal of Comparative Neurology | 1975 | 366 |
| 13 | Confronting Complexity: the Interlink of Phototransduction and Retinoid Metabolism in the Vertebrate Retina | Progress in Retinal and Eye Research | 2001 | 334 |
| 14 | The COMS randomized trial of iodine 125 brachytherapy for choroidal melanoma | Ophthalmology | 2002 | 327 |
| 15 | Lecithin-retinol Acyltransferase Is Essential for Accumulation of All-trans-Retinyl Esters in the Eye and in the Liver | Journal of Biological Chemistry | 2004 | 321 |
| 16 | Immunocytochemical localization of glutamic acid decarboxylase in monkey striate cortex | Nature | 1981 | 318 |
| 17 | Stromal-epithelial interactions in the cornea | Progress in Retinal and Eye Research | 1999 | 314 |
| 18 | Purification and physiological evaluation of a guanylate cyclase activating protein from retinal rods. | Proceedings of the National Academy of Sciences of the United States of America | 1994 | 308 |
| 19 | Recoverin immunoreactivity in mammalian cone bipolar cells | Visual Neuroscience | 1993 | 293 |
| 20 | Prevalence of mutations causing retinitis pigmentosa and other inherited retinopathies | Human Mutation | 2001 | 292 |
| 21 | Gene therapy for red–green colour blindness in adult primates | Nature | 2009 | 282 |
| 22 | The genetics of normal and defective color vision | Vision Research | 2011 | 278 |
| 23 | Deep-learning based, automated segmentation of macular edema in optical coherence tomography | Biomedical Optics Express | 2017 | 277 |
| 24 | Parasol and midget ganglion cells of the primate retina | Journal of Comparative Neurology | 1989 | 276 |
| 25 | Essential role of Ca2+-binding protein 4, a Cav1.4 channel regulator, in photoreceptor synaptic function | Nature Neuroscience | 2004 | 272 |
| 26 | Identification of specific transducin alpha subunits in retinal rod and cone photoreceptors | Science | 1986 | 267 |
| 27 | The density recovery profile: A method for the analysis of points in the plane applicable to retinal studies | Visual Neuroscience | 1991 | 261 |
| 28 | Synaptic Adjustment after Deafferentation of the Superior Colliculus of the Rat | Science | 1971 | 257 |
| 29 | Sequential phosphorylation of rhodopsin at multiple sites | Biochemistry | 1993 | 256 |
| 30 | Biochemical adaptations of the retina and retinal pigment epithelium support a metabolic ecosystem in the vertebrate eye | ELife | 2017 | 254 |
| 31 | Abnormalities in rod photoreceptors, amacrine cells, and horizontal cells in human retinas with retinitis pigmentosa | American Journal of Ophthalmology | 2000 | 245 |
| 32 | Prevalence of Amblyopia or Strabismus in Asian and Non-Hispanic White Preschool Children | Ophthalmology | 2013 | 232 |
| 33 | Five Members of a Novel Ca2+-binding Protein (CABP) Subfamily with Similarity to Calmodulin | Journal of Biological Chemistry | 2000 | 231 |
| 34 | Visual Cycle Impairment in Cellular Retinaldehyde Binding Protein (CRALBP) Knockout Mice Results in Delayed Dark Adaptation | Neuron | 2001 | 230 |
| 35 | Histologic Development of the Human Fovea From Midgestation to Maturity | American Journal of Ophthalmology | 2012 | 228 |
| 36 | Prevalence of Diabetes Mellitus and Impaired Glucose Tolerance Among Second-Generation Japanese-American Men | Diabetes | 1987 | 218 |
| 37 | Photochemical Restoration of Visual Responses in Blind Mice | Neuron | 2012 | 216 |
| 38 | Rod photoreceptor neurite sprouting in retinitis pigmentosa | Journal of Neuroscience | 1995 | 213 |
| 39 | Oligomerization of G Protein-Coupled Receptors: Past, Present, and Future† | Biochemistry | 2004 | 213 |
| 40 | HLA-B27 and Human β2-Microglobulin Affect the Gut Microbiota of Transgenic Rats | PLoS ONE | 2014 | 209 |
| 41 | Aqueous outflow - A continuum from trabecular meshwork to episcleral veins | Progress in Retinal and Eye Research | 2017 | 205 |
| 42 | Real-world outcomes in patients with neovascular age-related macular degeneration treated with intravitreal vascular endothelial growth factor inhibitors | Progress in Retinal and Eye Research | 2018 | 205 |
| 43 | Survey of the morphology of macaque retinal ganglion cells that project to the pretectum, superior colliculus, and parvicellular laminae of the lateral geniculate nucleus | Journal of Comparative Neurology | 1993 | 204 |
| 44 | Guanylyl Cyclase Activating Protein | Journal of Biological Chemistry | 1995 | 201 |
| 45 | The Effect of Phacoemulsification on Intraocular Pressure in Glaucoma Patients | Ophthalmology | 2015 | 200 |
| 46 | Retinal Vasculitis and Intraocular Inflammation after Intravitreal Injection of Brolucizumab | Ophthalmology | 2020 | 199 |
| 47 | The G protein-coupled receptor rhodopsin in the native membrane | FEBS Letters | 2004 | 196 |
| 48 | Histopathology and Immunocytochemistry of the Neurosensory Retina in Fundus Flavimaculatus | Ophthalmology | 1994 | 195 |
| 49 | Maturation of the Human Fovea: Correlation of Spectral-Domain Optical Coherence Tomography Findings With Histology | American Journal of Ophthalmology | 2012 | 193 |
| 50 | Histopathology of Bone Spicule Pigmentation in Retinitis Pigmentosa | Ophthalmology | 1995 | 192 |
