| # | Title | Journal | Year | Citations |
|---|
| 1 | Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the Intensive Care Unit | Critical Care Medicine | 2013 | 3,066 |
| 2 | From local explanations to global understanding with explainable AI for trees | Nature Machine Intelligence | 2020 | 2,869 |
| 3 | Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU | Critical Care Medicine | 2018 | 2,074 |
| 4 | Management of Postoperative Pain: A Clinical Practice Guideline From the American Pain Society, the American Society of Regional Anesthesia and Pain Medicine, and the American Society of Anesthesiologists' Committee on Regional Anesthesia, Executive Committee, and Administrative Council | Journal of Pain | 2016 | 2,040 |
| 5 | Global, Regional, and National Prevalence, Incidence, and Disability-Adjusted Life Years for Oral Conditions for 195 Countries, 1990–2015: A Systematic Analysis for the Global Burden of Diseases, Injuries, and Risk Factors | Journal of Dental Research | 2017 | 1,146 |
| 6 | Explainable machine-learning predictions for the prevention of hypoxaemia during surgery | Nature Biomedical Engineering | 2018 | 1,033 |
| 7 | Critical care and the global burden of critical illness in adults | Lancet, The | 2010 | 976 |
| 8 | NMR Spectroscopy for Metabolomics Research | Metabolites | 2019 | 627 |
| 9 | Treatment of chronic non-cancer pain | Lancet, The | 2011 | 571 |
| 10 | Prevalence and impact of pain among older adults in the United States: Findings from the 2011 National Health and Aging Trends Study | Pain | 2013 | 559 |
| 11 | Global Burden of Severe Tooth Loss | Journal of Dental Research | 2014 | 445 |
| 12 | Detection of Succinate by Intestinal Tuft Cells Triggers a Type 2 Innate Immune Circuit | Immunity | 2018 | 380 |
| 13 | Mitochondrial Complex I Deficiency Increases Protein Acetylation and Accelerates Heart Failure | Cell Metabolism | 2013 | 376 |
| 14 | Sleep Health: Reciprocal Regulation of Sleep and Innate Immunity | Neuropsychopharmacology | 2017 | 344 |
| 15 | Actionable, Pathogenic Incidental Findings in 1,000 Participants’ Exomes | American Journal of Human Genetics | 2013 | 342 |
| 16 | Family and parent influences on pediatric chronic pain: A developmental perspective. | American Psychologist | 2014 | 327 |
| 17 | Actionable exomic incidental findings in 6503 participants: challenges of variant classification | Genome Research | 2015 | 313 |
| 18 | Gait Speed Predicts Incident Disability: A Pooled Analysis | Journals of Gerontology - Series A Biological Sciences and Medical Sciences | 2016 | 293 |
| 19 | Assessment of patients with chronic pain | British Journal of Anaesthesia | 2013 | 292 |
| 20 | Patterns of Technology Use Among Older Adults With and Without Disabilities | Gerontologist, The | 2015 | 289 |
| 21 | Defective Branched-Chain Amino Acid Catabolism Disrupts Glucose Metabolism and Sensitizes the Heart to Ischemia-Reperfusion Injury | Cell Metabolism | 2017 | 289 |
| 22 | Randomized Trial of Communication Facilitators to Reduce Family Distress and Intensity of End-of-Life Care | American Journal of Respiratory and Critical Care Medicine | 2016 | 280 |
| 23 | Limitations of Animal Studies for Predicting Toxicity in Clinical Trials | JACC Basic To Translational Science | 2019 | 274 |
| 24 | Cell Biology of the Mitochondrion | Genetics | 2017 | 265 |
| 25 | Altered proteome turnover and remodeling by short‐term caloric restriction or rapamycin rejuvenate the aging heart | Aging Cell | 2014 | 264 |
| 26 | Core outcome measurement instruments for clinical trials in nonspecific low back pain | Pain | 2018 | 263 |
| 27 | Drugs, Devices, and the FDA: Part 1 | JACC Basic To Translational Science | 2016 | 233 |
| 28 | Metabolic Signatures of Bacterial Vaginosis | MBio | 2015 | 230 |
| 29 | Executive Summary: Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU | Critical Care Medicine | 2018 | 197 |
| 30 | EGFR Signaling Enhances Aerobic Glycolysis in Triple-Negative Breast Cancer Cells to Promote Tumor Growth and Immune Escape | Cancer Research | 2016 | 190 |
| 31 | Targeting Mitochondria-Inflammation Circuit by β-Hydroxybutyrate Mitigates HFpEF | Circulation Research | 2021 | 190 |
| 32 | Opioids Compared With Placebo or Other Treatments for Chronic Low Back Pain | Spine | 2014 | 184 |
| 33 | Revised American Pain Society Patient Outcome Questionnaire (APS-POQ-R) for Quality Improvement of Pain Management in Hospitalized Adults: Preliminary Psychometric Evaluation | Journal of Pain | 2010 | 178 |
| 34 | Death or Neurologic Injury after Tonsillectomy in Children with a Focus on Obstructive Sleep Apnea | Anesthesia and Analgesia | 2014 | 176 |
| 35 | Central sensitisation in chronic pain conditions: latest discoveries and their potential for precision medicine | Lancet Rheumatology, The | 2021 | 176 |
| 36 | Colorectal Cancer Detection Using Targeted Serum Metabolic Profiling | Journal of Proteome Research | 2014 | 174 |
| 37 | Deregulated Myc Requires MondoA/Mlx for Metabolic Reprogramming and Tumorigenesis | Cancer Cell | 2015 | 172 |
| 38 | Exogenously applied muscle metabolites synergistically evoke sensations of muscle fatigue and pain in human subjects | Experimental Physiology | 2014 | 166 |
| 39 | Opioids compared to placebo or other treatments for chronic low-back pain | The Cochrane Library | 2013 | 163 |
| 40 | The ACTTION-American Pain Society Pain Taxonomy (AAPT): An Evidence-Based and Multidimensional Approach to Classifying Chronic Pain Conditions | Journal of Pain | 2014 | 159 |
| 41 | Drugs and Devices | JACC Basic To Translational Science | 2016 | 154 |
| 42 | Assessment of physical function and participation in chronic pain clinical trials: IMMPACT/OMERACT recommendations | Pain | 2016 | 152 |
| 43 | CaMKII induces permeability transition through Drp1 phosphorylation during chronic β-AR stimulation | Nature Communications | 2016 | 151 |
| 44 | Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit: Executive summary | American Journal of Health-System Pharmacy | 2013 | 150 |
| 45 | Recommendations for Preoperative Management of Frailty from the Society for Perioperative Assessment and Quality Improvement (SPAQI) | Journal of Clinical Anesthesia | 2018 | 145 |
| 46 | The role of microglia in adult hippocampal neurogenesis | Frontiers in Cellular Neuroscience | 2013 | 141 |
| 47 | Development and Validation of a Prediction Model for Pain and Functional Outcomes After Lumbar Spine Surgery | JAMA Surgery | 2018 | 139 |
| 48 | Drugs, Devices, and the FDA: Part 2 | JACC Basic To Translational Science | 2016 | 135 |
| 49 | Metabolic Remodeling Promotes Cardiac Hypertrophy by Directing Glucose to Aspartate Biosynthesis | Circulation Research | 2020 | 135 |
| 50 | Physical capability in mid-life and survival over 13 years of follow-up: British birth cohort study | BMJ, The | 2014 | 133 |
