| # | Title | Journal | Year | Citations |
|---|
| 1 | Role of Insulin Resistance in Human Disease | Diabetes | 1988 | 10,677 |
| 2 | Physician burnout: contributors, consequences and solutions | Journal of Internal Medicine | 2018 | 1,369 |
| 3 | Prediction of Survival in Diffuse Large-B-Cell Lymphoma Based on the Expression of Six Genes | New England Journal of Medicine | 2004 | 874 |
| 4 | Phase I clinical trial using escalating single-dose infusion of chimeric anti-CD20 monoclonal antibody (IDEC-C2B8) in patients with recurrent B-cell lymphoma | Blood | 1994 | 673 |
| 5 | Quantitative assessment of single-cell RNA-sequencing methods | Nature Methods | 2014 | 670 |
| 6 | Use of a SCID mouse/human lymphoma model to evaluate cytokine-induced killer cells with potent antitumor cell activity. | Journal of Experimental Medicine | 1991 | 544 |
| 7 | The tetraspanin web modulates immune-signalling complexes | Nature Reviews Immunology | 2005 | 537 |
| 8 | Pancreatic tumors show high levels of hypoxia | International Journal of Radiation Oncology Biology Physics | 2000 | 519 |
| 9 | Endotoxin-induced uveitis in rats as a model for human disease | Nature | 1980 | 483 |
| 10 | The long-term course of cyclosporine-associated chronic nephropathy | Kidney International | 1988 | 474 |
| 11 | CD81 (TAPA-1): A MOLECULE INVOLVED IN SIGNAL TRANSDUCTION AND CELL ADHESION IN THE IMMUNE SYSTEM | Annual Review of Immunology | 1998 | 472 |
| 12 | Type IV Pili, Transient Bacterial Aggregates, and Virulence of Enteropathogenic Escherichia coli | Science | 1998 | 440 |
| 13 | Prognostic significance of actual dose intensity in diffuse large-cell lymphoma: results of a tree-structured survival analysis. | Journal of Clinical Oncology | 1990 | 421 |
| 14 | Association of Antibodies to Ribonucleoprotein and Sm Antigens with Mixed Connective-Tissue Disease, Systemic Lupus Erythematosus and Other Rheumatic Diseases | New England Journal of Medicine | 1976 | 391 |
| 15 | Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein | Nature | 1996 | 382 |
| 16 | Tumor Necrosis Factor Causes Increased Pulmonary Permeability and Edema: Comparison to Septic Acute Lung Injury | The American Review of Respiratory Disease | 1988 | 378 |
| 17 | The origins of the identification and isolation of hematopoietic stem cells, and their capability to induce donor-specific transplantation tolerance and treat autoimmune diseases | Blood | 2008 | 366 |
| 18 | A novel population of expanded human CD3+CD56+ cells derived from T cells with potent in vivo antitumor activity in mice with severe combined immunodeficiency. | Journal of Immunology | 1994 | 366 |
| 19 | Molecular Biology and Function of CD4 and CD8 | Advances in Immunology | 1989 | 356 |
| 20 | Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA | Science | 1994 | 353 |
| 21 | Immunotherapy of the nonobese diabetic mouse: treatment with an antibody to T-helper lymphocytes | Science | 1988 | 346 |
| 22 | Use of Reporter Genes for Optical Measurements of Neoplastic Disease In Vivo | Neoplasia | 2000 | 337 |
| 23 | A novel population of expanded human CD3+CD56+ cells derived from T cells with potent in vivo antitumor activity in mice with severe combined immunodeficiency | Journal of Immunology | 1994 | 330 |
| 24 | Hepatocyte CD81 is required for Plasmodium falciparum and Plasmodium yoelii sporozoite infectivity | Nature Medicine | 2003 | 327 |
| 25 | High-Dose Therapy and Autologous Hematopoietic Progenitor Cell Transplantation for Recurrent or Refractory Hodgkin's Disease: Analysis of the Stanford University Results and Prognostic Indices | Blood | 1997 | 313 |
| 26 | Striking Prevalence of Ankylosing Spondylitis in “Healthy” W27 Positive Males and Females | New England Journal of Medicine | 1975 | 302 |
| 27 | CELLS MEDIATING ALLOGRAFT REJECTION | Transplantation | 1991 | 302 |
| 28 | Predictive factors of response and survival in myelodysplastic syndrome treated with erythropoietin and G-CSF: the GFM experience | Blood | 2008 | 295 |
| 29 | Enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56lck | Nature | 1991 | 294 |
| 30 | Impaired dendritic cell maturation in patients with chronic, but not resolved, hepatitis C virus infection | Blood | 2001 | 291 |
| 31 | Granulocyte colony-stimulating factor "mobilized" peripheral blood progenitor cells accelerate granulocyte and platelet recovery after high-dose chemotherapy | Blood | 1993 | 288 |
| 32 | Objective responses in relapsed T-cell lymphomas with single-agent brentuximab vedotin | Blood | 2014 | 280 |
| 33 | Expression of a single gene, BCL-6, strongly predicts survival in patients with diffuse large B-cell lymphoma | Blood | 2001 | 272 |
| 34 | Stanford V and Radiotherapy for Locally Extensive and Advanced Hodgkin’s Disease: Mature Results of a Prospective Clinical Trial | Journal of Clinical Oncology | 2002 | 261 |
| 35 | Phenotypic characterization and identification of effector cells involved in tumor cell recognition of cytokine-induced killer cells | Experimental Hematology | 1993 | 258 |
| 36 | Ulcerative Tracheobronchitis after Lung Transplantation: A New Form of Invasive Aspergillosis | The American Review of Respiratory Disease | 1991 | 257 |
| 37 | DNA immunization induces protective immunity against B–cell lymphoma | Nature Medicine | 1996 | 245 |
| 38 | Clonal evolution of a follicular lymphoma: evidence for antigen selection. | Proceedings of the National Academy of Sciences of the United States of America | 1992 | 242 |
| 39 | Screening for Coronary Artery Disease After Mediastinal Irradiation for Hodgkin's Disease | Journal of Clinical Oncology | 2007 | 236 |
| 40 | The Diagnosis and Management of Benign Hepatic Tumors | Journal of Clinical Gastroenterology | 2005 | 232 |
| 41 | Chemotherapeutic agents and the skin: An update | Journal of the American Academy of Dermatology | 2008 | 231 |
| 42 | Doxorubicin selectively inhibits muscle gene expression in cardiac muscle cells in vivo and in vitro. | Proceedings of the National Academy of Sciences of the United States of America | 1990 | 230 |
| 43 | Maintenance treatment of patients with myelodysplastic syndromes using recombinant human granulocyte colony-stimulating factor | Blood | 1990 | 229 |
| 44 | Cancer Risk After Use of Recombinant Bone Morphogenetic Protein-2 for Spinal Arthrodesis | Journal of Bone and Joint Surgery - Series A | 2013 | 228 |
| 45 | Sequence analysis of cDNAs for the human and bovine ATP synthase ? subunit: mitochondrial DNA genes sustain seventeen times more mutations | Current Genetics | 1987 | 223 |
| 46 | Reconstitution of MHC class I specificity by transfer of the T cell receptor and Lyt-2 genes | Cell | 1987 | 221 |
| 47 | Expansion of cytolytic CD8+ natural killer T cells with limited capacity for graft-versus-host disease induction due to interferon γ production | Blood | 2001 | 218 |
| 48 | Chronic hepatitis B: Virology, natural history, current management and a glimpse at future opportunities | Antiviral Research | 2015 | 216 |
| 49 | Perioperative Glycemic Control | Anesthesiology | 2009 | 214 |
| 50 | Stage I and II Follicular Non-Hodgkin’s Lymphoma: Long-Term Follow-Up of No Initial Therapy | Journal of Clinical Oncology | 2004 | 211 |
