| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 | Cell Death and Differentiation | 2018 | 4,036 |
| 3 | Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer | Science | 2005 | 3,541 |
| 4 | A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C | Hepatology | 2003 | 3,455 |
| 5 | ONCOMINE: A Cancer Microarray Database and Integrated Data-Mining Platform | Neoplasia | 2004 | 3,212 |
| 6 | NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals | Nature | 2010 | 3,130 |
| 7 | bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death | Cell | 1993 | 2,976 |
| 8 | FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex | Cell | 1996 | 2,944 |
| 9 | The polycomb group protein EZH2 is involved in progression of prostate cancer | Nature | 2002 | 2,411 |
| 10 | Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase | Cell | 1995 | 2,396 |
| 11 | FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis | Cell | 1995 | 2,298 |
| 12 | Oncogenic Signaling Pathways in The Cancer Genome Atlas | Cell | 2018 | 2,111 |
| 13 | Oncomine 3.0: Genes, Pathways, and Networks in a Collection of 18,000 Cancer Gene Expression Profiles | Neoplasia | 2007 | 1,847 |
| 14 | The Myofibroblast | American Journal of Pathology | 2007 | 1,782 |
| 15 | Inhibition of Adipogenesis by Wnt Signaling | Science | 2000 | 1,705 |
| 16 | The Receptor for the Cytotoxic Ligand TRAIL | Science | 1997 | 1,665 |
| 17 | The Emergence of lncRNAs in Cancer Biology | Cancer Discovery | 2011 | 1,612 |
| 18 | Delineation of prognostic biomarkers in prostate cancer | Nature | 2001 | 1,551 |
| 19 | Immunodesign of experimental sepsis by cecal ligation and puncture | Nature Protocols | 2009 | 1,535 |
| 20 | CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy | Nature | 2019 | 1,528 |
| 21 | Increased bone formation in osteocalcin-deficient mice | Nature | 1996 | 1,522 |
| 22 | EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 1,482 |
| 23 | An Antagonist Decoy Receptor and a Death Domain-Containing Receptor for TRAIL | Science | 1997 | 1,455 |
| 24 | Ion Suppression in Mass Spectrometry | Clinical Chemistry | 2003 | 1,396 |
| 25 | Molecular basis of sun-induced premature skin ageing and retinoid antagonism | Nature | 1996 | 1,312 |
| 26 | Analysis of shared heritability in common disorders of the brain | Science | 2018 | 1,085 |
| 27 | IRAK (Pelle) Family Member IRAK-2 and MyD88 as Proximal Mediators of IL-1 Signaling | Science | 1997 | 1,082 |
| 28 | Cancer to bone: a fatal attraction | Nature Reviews Cancer | 2011 | 1,047 |
| 29 | p53-Mediated Activation of miRNA34 Candidate Tumor-Suppressor Genes | Current Biology | 2007 | 1,045 |
| 30 | Recent Developments in Myofibroblast Biology | American Journal of Pathology | 2012 | 1,043 |
| 31 | Netting Neutrophils Induce Endothelial Damage, Infiltrate Tissues, and Expose Immunostimulatory Molecules in Systemic Lupus Erythematosus | Journal of Immunology | 2011 | 1,039 |
| 32 | TRAF2-Mediated Activation of NF-κB by TNF Receptor 2 and CD40 | Science | 1995 | 1,033 |
| 33 | Adhesion molecules and inflammatory injury | FASEB Journal | 1994 | 936 |
| 34 | Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy | Nature | 2015 | 897 |
| 35 | An Induced Proximity Model for Caspase-8 Activation | Journal of Biological Chemistry | 1998 | 879 |
| 36 | Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 874 |
| 37 | ROLE OF C5A IN INFLAMMATORY RESPONSES | Annual Review of Immunology | 2005 | 855 |
| 38 | Generation of C5a in the absence of C3: a new complement activation pathway | Nature Medicine | 2006 | 845 |
| 39 | Neonatal gut microbiota associates with childhood multisensitized atopy and T cell differentiation | Nature Medicine | 2016 | 844 |
| 40 | Integrative molecular concept modeling of prostate cancer progression | Nature Genetics | 2007 | 837 |
| 41 | Molecular basis of phenotypic variability in sporadc creudeldt‐jakob disease | Annals of Neurology | 1996 | 819 |
| 42 | Androgen-Independent Prostate Cancer Is a Heterogeneous Group of Diseases | Cancer Research | 2004 | 816 |
| 43 | Androgen Receptor Regulates a Distinct Transcription Program in Androgen-Independent Prostate Cancer | Cell | 2009 | 797 |
| 44 | Endothelial cell gene expression of a neutrophil chemotactic factor by TNF-alpha, LPS, and IL-1 beta | Science | 1989 | 795 |
| 45 | Novel strategies for the treatment of sepsis | Nature Medicine | 2003 | 769 |
| 46 | The NLR Gene Family: A Standard Nomenclature | Immunity | 2008 | 761 |
| 47 | Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity | Cell | 2013 | 753 |
| 48 | Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer | Nature | 2007 | 743 |
| 49 | An Integrated Network of Androgen Receptor, Polycomb, and TMPRSS2-ERG Gene Fusions in Prostate Cancer Progression | Cancer Cell | 2010 | 743 |
| 50 | Neutralization of Groα and Macrophage Inflammatory Protein-2 Attenuates Renal Ischemia/Reperfusion Injury | American Journal of Pathology | 2001 | 734 |
