| # | Title | Journal | Year | Citations |
|---|
| 1 | The Myofibroblast | American Journal of Pathology | 2007 | 1,782 |
| 2 | Leukotrienes | New England Journal of Medicine | 2007 | 941 |
| 3 | NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury | Nature Medicine | 2009 | 741 |
| 4 | Extracorporeal membrane oxygenation support in COVID-19: an international cohort study of the Extracorporeal Life Support Organization registry | Lancet, The | 2020 | 656 |
| 5 | Mechanisms of Pulmonary Fibrosis | Annual Review of Medicine | 2004 | 640 |
| 6 | The Microbiome and the Respiratory Tract | Annual Review of Physiology | 2016 | 622 |
| 7 | Analysis of the Upper Respiratory Tract Microbiotas as the Source of the Lung and Gastric Microbiotas in Healthy Individuals | MBio | 2015 | 601 |
| 8 | Idiopathic Interstitial Pneumonia | American Journal of Respiratory and Critical Care Medicine | 2004 | 574 |
| 9 | Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis | American Journal of Physiology - Lung Cellular and Molecular Physiology | 2015 | 570 |
| 10 | Acellular Normal and Fibrotic Human Lung Matrices as a Culture System for In Vitro Investigation | American Journal of Respiratory and Critical Care Medicine | 2012 | 552 |
| 11 | Myofibroblast Differentiation by Transforming Growth Factor-ॆ1 Is Dependent on Cell Adhesion and Integrin Signaling via Focal Adhesion Kinase | Journal of Biological Chemistry | 2003 | 547 |
| 12 | Chronic lung allograft dysfunction: Definition, diagnostic criteria, and approaches to treatment―A consensus report from the Pulmonary Council of the ISHLT | Journal of Heart and Lung Transplantation | 2019 | 518 |
| 13 | Radiological versus histological diagnosis in UIP and NSIP: survival implications | Thorax | 2003 | 481 |
| 14 | Prognostic Implications of Physiologic and Radiographic Changes in Idiopathic Interstitial Pneumonia | American Journal of Respiratory and Critical Care Medicine | 2003 | 461 |
| 15 | Enrichment of the lung microbiome with gut bacteria in sepsis and the acute respiratory distress syndrome | Nature Microbiology | 2016 | 433 |
| 16 | Does the microbiota regulate immune responses outside the gut? | Trends in Microbiology | 2004 | 416 |
| 17 | Targeted Injury of Type II Alveolar Epithelial Cells Induces Pulmonary Fibrosis | American Journal of Respiratory and Critical Care Medicine | 2010 | 399 |
| 18 | Spatial Variation in the Healthy Human Lung Microbiome and the Adapted Island Model of Lung Biogeography | Annals of the American Thoracic Society | 2015 | 390 |
| 19 | The Lung Microbiome: New Principles for Respiratory Bacteriology in Health and Disease | PLoS Pathogens | 2015 | 390 |
| 20 | Fluticasone furoate and vilanterol and survival in chronic obstructive pulmonary disease with heightened cardiovascular risk (SUMMIT): a double-blind randomised controlled trial | Lancet, The | 2016 | 378 |
| 21 | The role of the microbiome in exacerbations of chronic lung diseases | Lancet, The | 2014 | 366 |
| 22 | Bacterial Topography of the Healthy Human Lower Respiratory Tract | MBio | 2017 | 366 |
| 23 | International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci | Nature Communications | 2019 | 363 |
| 24 | Clinical and Radiologic Disease in Smokers With Normal Spirometry | JAMA Internal Medicine | 2015 | 360 |
| 25 | Diagnosis, Assessment, and Treatment of Non-Pulmonary Arterial Hypertension Pulmonary Hypertension | Journal of the American College of Cardiology | 2009 | 353 |
| 26 | Clinical significance of histological classification of idiopathic interstitial pneumonia | European Respiratory Journal | 2002 | 345 |
| 27 | The instructive extracellular matrix of the lung: basic composition and alterations in chronic lung disease | European Respiratory Journal | 2017 | 341 |
| 28 | The respiratory tract microbiome and lung inflammation: a two-way street | Mucosal Immunology | 2017 | 338 |
| 29 | Idiopathic Pulmonary Fibrosis | American Journal of Respiratory and Critical Care Medicine | 2006 | 333 |
| 30 | The 'microflora hypothesis' of allergic diseases | Clinical and Experimental Allergy | 2005 | 326 |
| 31 | The role of the bacterial microbiome in lung disease | Expert Review of Respiratory Medicine | 2013 | 323 |
| 32 | The microbiome and critical illness | Lancet Respiratory Medicine,the | 2016 | 323 |
| 33 | Evolving Concepts of Apoptosis in Idiopathic Pulmonary Fibrosis | Proceedings of the American Thoracic Society | 2006 | 310 |
| 34 | The microbiome of the lung | Translational Research | 2012 | 297 |
| 35 | Gender and Chronic Obstructive Pulmonary Disease | American Journal of Respiratory and Critical Care Medicine | 2007 | 293 |
| 36 | The Lung Microbiome, Immunity, and the Pathogenesis of Chronic Lung Disease | Journal of Immunology | 2016 | 291 |
| 37 | New insights into form and function of fibronectin splice variants | Journal of Pathology | 2008 | 288 |
| 38 | Lung-volume reduction improves dyspnea, dynamic hyperinflation, and respiratory muscle function. | American Journal of Respiratory and Critical Care Medicine | 1997 | 282 |
| 39 | Role of Antibiotics and Fungal Microbiota in Driving Pulmonary Allergic Responses | Infection and Immunity | 2004 | 282 |
| 40 | Evidence for tissue-resident mesenchymal stem cells in human adult lung from studies of transplanted allografts | Journal of Clinical Investigation | 2007 | 272 |
| 41 | The microbiome and regulation of mucosal immunity | Immunology | 2014 | 271 |
| 42 | An Essential Role for Fibronectin Extra Type III Domain A in Pulmonary Fibrosis | American Journal of Respiratory and Critical Care Medicine | 2008 | 257 |
| 43 | Extracorporeal membrane oxygenation for COVID-19: evolving outcomes from the international Extracorporeal Life Support Organization Registry | Lancet, The | 2021 | 257 |
| 44 | Neutralization of Macrophage Inflammatory Protein-2 Attenuates Neutrophil Recruitment and Bacterial Clearance in Murine Klebsiella Pneumonia | Journal of Infectious Diseases | 1996 | 251 |
| 45 | Arachidonic Acid Is Preferentially Metabolized by Cyclooxygenase-2 to Prostacyclin and Prostaglandin E2 | Journal of Biological Chemistry | 1999 | 250 |
| 46 | PULMONARY SARCOIDOSIS | Clinics in Chest Medicine | 1997 | 245 |
| 47 | Bleomycin-induced pulmonary fibrosis in fibrinogen-null mice | Journal of Clinical Investigation | 2000 | 243 |
| 48 | Towards an ecology of the lung: new conceptual models of pulmonary microbiology and pneumonia pathogenesis | Lancet Respiratory Medicine,the | 2014 | 242 |
| 49 | Development of Allergic Airway Disease in Mice following Antibiotic Therapy and Fungal Microbiota Increase: Role of Host Genetics, Antigen, and Interleukin-13 | Infection and Immunity | 2005 | 238 |
| 50 | Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts | FASEB Journal | 2005 | 234 |
