| # | Title | Journal | Year | Citations |
|---|
| 1 | Prospective identification of tumorigenic breast cancer cells | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 9,314 |
| 2 | Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial | Lancet, The | 1998 | 5,398 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 4 | In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro | Nature Protocols | 2007 | 3,638 |
| 5 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 6 | Oncogenic Signaling Pathways in The Cancer Genome Atlas | Cell | 2018 | 2,111 |
| 7 | Long-term Cognitive Impairment and Functional Disability Among Survivors of Severe Sepsis | JAMA - Journal of the American Medical Association | 2010 | 1,872 |
| 8 | The Myofibroblast | American Journal of Pathology | 2007 | 1,782 |
| 9 | Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B. | Proceedings of the National Academy of Sciences of the United States of America | 1989 | 1,666 |
| 10 | Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease | Annals of Neurology | 1997 | 1,576 |
| 11 | Genome-Wide Association Scan Shows Genetic Variants in the FTO Gene Are Associated with Obesity-Related Traits | PLoS Genetics | 2007 | 1,446 |
| 12 | Molecular Genetics of Colorectal Cancer | Annual Review of Pathology: Mechanisms of Disease | 2011 | 1,424 |
| 13 | A Validated Prediction Model for All Forms of Acute Coronary Syndrome | JAMA - Journal of the American Medical Association | 2004 | 1,344 |
| 14 | Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young (MODY3) | Nature | 1996 | 1,240 |
| 15 | The gut microbiome in health and in disease | Current Opinion in Gastroenterology | 2015 | 1,193 |
| 16 | Mutations in the hepatocyte nuclear factor-4α gene in maturity-onset diabetes of the young (MODY1) | Nature | 1996 | 1,114 |
| 17 | p53-Mediated Activation of miRNA34 Candidate Tumor-Suppressor Genes | Current Biology | 2007 | 1,045 |
| 18 | Netting Neutrophils Induce Endothelial Damage, Infiltrate Tissues, and Expose Immunostimulatory Molecules in Systemic Lupus Erythematosus | Journal of Immunology | 2011 | 1,039 |
| 19 | Efficient transfer of genetic material into mammalian cells using Starburst polyamidoamine dendrimers. | Proceedings of the National Academy of Sciences of the United States of America | 1996 | 995 |
| 20 | Major trends in the microbial etiology of nosocomial infection | American Journal of Medicine | 1991 | 994 |
| 21 | Histoplasmosis: a Clinical and Laboratory Update | Clinical Microbiology Reviews | 2007 | 978 |
| 22 | Molecular Mechanisms and Clinical Pathophysiology of Maturity-Onset Diabetes of the Young | New England Journal of Medicine | 2001 | 968 |
| 23 | Endoplasmic reticulum stress in liver disease | Journal of Hepatology | 2011 | 952 |
| 24 | Leukotrienes | New England Journal of Medicine | 2007 | 941 |
| 25 | Neutrophil Extracellular Traps: Double-Edged Swords of Innate Immunity | Journal of Immunology | 2012 | 933 |
| 26 | Activating ESR1 mutations in hormone-resistant metastatic breast cancer | Nature Genetics | 2013 | 925 |
| 27 | RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly | Cell | 2007 | 906 |
| 28 | Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies | Nature Genetics | 2018 | 896 |
| 29 | DELAYED GRAFT FUNCTION: RISK FACTORS AND IMPLICATIONS FOR RENAL ALLOGRAFT SURVIVAL1 | Transplantation | 1997 | 871 |
| 30 | Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans | Proceedings of the National Academy of Sciences of the United States of America | 1993 | 850 |
| 31 | Th17 Cell Induction by Adhesion of Microbes to Intestinal Epithelial Cells | Cell | 2015 | 846 |
| 32 | Using Raman spectroscopy to characterize biological materials | Nature Protocols | 2016 | 833 |
| 33 | Endothelial cell gene expression of a neutrophil chemotactic factor by TNF-alpha, LPS, and IL-1 beta | Science | 1989 | 795 |
| 34 | Modelling human development and disease in pluripotent stem-cell-derived gastric organoids | Nature | 2014 | 792 |
| 35 | The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds | Nature Genetics | 1996 | 775 |
| 36 | Hippocampal formation volume, memory dysfunction, and cortisol levels in patients with Cushing's syndrome | Biological Psychiatry | 1992 | 771 |
| 37 | Pitfalls in Oncologic Diagnosis with FDG PET Imaging: Physiologic and Benign Variants | Radiographics | 1999 | 757 |
| 38 | NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury | Nature Medicine | 2009 | 741 |
| 39 | Microsatellite instability in colorectal cancer—the stable evidence | Nature Reviews Clinical Oncology | 2010 | 736 |
| 40 | Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia | Science | 1993 | 730 |
| 41 | The α(1,3)Fucosyltransferase Fuc-TVII Controls Leukocyte Trafficking through an Essential Role in L-, E-, and P-selectin Ligand Biosynthesis | Cell | 1996 | 704 |
| 42 | 131I-Tositumomab Therapy as Initial Treatment for Follicular Lymphoma | New England Journal of Medicine | 2005 | 697 |
| 43 | HTLV-1 transactivator induces interleukin-2 receptor expression through an NF-κB-like factor | Nature | 1988 | 693 |
| 44 | Diagnosis and Cure of the Wolff–Parkinson–White Syndrome or Paroxysmal Supraventricular Tachycardias during a Single Electrophysiologic Test | New England Journal of Medicine | 1991 | 692 |
| 45 | Matrix Metalloproteinases Regulate Neovascularization by Acting as Pericellular Fibrinolysins | Cell | 1998 | 676 |
| 46 | Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing | Nature Genetics | 2013 | 662 |
| 47 | Murine models of pulmonary fibrosis | American Journal of Physiology - Lung Cellular and Molecular Physiology | 2008 | 656 |
| 48 | Podocyte Depletion Causes Glomerulosclerosis: Diphtheria Toxin–Induced Podocyte Depletion in Rats Expressing Human Diphtheria Toxin Receptor Transgene | Journal of the American Society of Nephrology: JASN | 2005 | 649 |
| 49 | Activation of HIV gene expression during monocyte differentiation by induction of NF-kB | Nature | 1989 | 635 |
| 50 | The PDBbind Database: Methodologies and Updates | Journal of Medicinal Chemistry | 2005 | 632 |
