Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients | New England Journal of Medicine | 2008 | 1.5K |
From endoplasmic-reticulum stress to the inflammatory response | Nature | 2008 | 1.4K |
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer | Science | 2008 | 888 |
Mechanisms of leptin action and leptin resistance | Annual Review of Physiology | 2008 | 749 |
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells | Journal of Cell Biology | 2008 | 716 |
Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes | Diabetes | 2008 | 633 |
Causes, clinical features, and outcomes from a prospective study of drug-induced liver injury in the United States | Gastroenterology | 2008 | 620 |
The right ventricular failure risk score a pre-operative tool for assessing the risk of right ventricular failure in left ventricular assist device candidates | Journal of the American College of Cardiology | 2008 | 559 |
Recurrent gene fusions in prostate cancer | Nature Reviews Cancer | 2008 | 554 |
Murine models of pulmonary fibrosis | American Journal of Physiology - Lung Cellular and Molecular Physiology | 2008 | 548 |
Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes | Journal of Clinical Investigation | 2008 | 514 |
Bimolecular fluorescence complementation (BiFC) analysis as a probe of protein interactions in living cells | Annual Review of Biophysics | 2008 | 487 |
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21 | Nature Genetics | 2008 | 486 |
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators | Developmental Cell | 2008 | 436 |
The unfolded protein response: a pathway that links insulin demand with beta-cell failure and diabetes | Endocrine Reviews | 2008 | 418 |
Pharmacokinetics of curcumin conjugate metabolites in healthy human subjects | Cancer Epidemiology Biomarkers and Prevention | 2008 | 350 |
Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke | Nature Medicine | 2008 | 343 |
A meta-analysis of pedometer-based walking interventions and weight loss | Annals of Family Medicine | 2008 | 312 |
Neurofibromin regulation of ERK signaling modulates GABA release and learning | Cell | 2008 | 311 |
MR Imaging of hepatocellular carcinoma in the cirrhotic liver: challenges and controversies | Radiology | 2008 | 303 |
Complicated acute type B dissection: is surgery still the best option?: a report from the International Registry of Acute Aortic Dissection | JACC: Cardiovascular Interventions | 2008 | 303 |
Cyclic AMP: master regulator of innate immune cell function | American Journal of Respiratory Cell and Molecular Biology | 2008 | 262 |
Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion | Endocrinology | 2008 | 258 |
Isolation and molecular characterization of cancer stem cells in MMTV-Wnt-1 murine breast tumors | Stem Cells | 2008 | 244 |
CT urography: definition, indications and techniques. A guideline for clinical practice | European Radiology | 2008 | 236 |