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Wallenberg Neuroscience Center
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top-articles
Wallenberg Neuroscience Center
456
(top 1%)
papers
38.0K
(top 0.1%)
citations
105
(top 0.1%)
h
-index
178
(top 0.1%)
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486
all documents
39.9K
doc citations
3.0K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Pathogenesis of parkinson's disease: dopamine, vesicles and α-synuclein
Nature Reviews Neuroscience
2002
1,070
2
Cell replacement therapies for central nervous system disorders
Nature Neuroscience
2000
897
3
Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats
Acta Neuropathologica
2014
708
4
Direct conversion of human fibroblasts to dopaminergic neurons
Proceedings of the National Academy of Sciences of the United States of America
2011
695
5
Parkinson-Like Neurodegeneration Induced by Targeted Overexpression of α-Synuclein in the Nigrostriatal System
Journal of Neuroscience
2002
633
6
TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity
Proceedings of the National Academy of Sciences of the United States of America
2013
600
7
Characterization of Behavioral and Neurodegenerative Changes Following Partial Lesions of the Nigrostriatal Dopamine System Induced by Intrastriatal 6-Hydroxydopamine in the Rat
Experimental Neurology
1998
576
8
A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease
Journal of Experimental Medicine
2008
559
9
Increased Sensitivity to N-Methyl-D-Aspartate Receptor-Mediated Excitotoxicity in a Mouse Model of Huntington's Disease
Neuron
2002
553
10
Site-Specific Migration and Neuronal Differentiation of Human Neural Progenitor Cells after Transplantation in the Adult Rat Brain
Journal of Neuroscience
1999
542
11
L-DOPA-induced dyskinesia in the rat is associated with striatal overexpression of prodynorphin- and glutamic acid decarboxylase mRNA
European Journal of Neuroscience
1998
533
12
Identification of Two Distinct Progenitor Populations in the Lateral Ganglionic Eminence: Implications for Striatal and Olfactory Bulb Neurogenesis
Journal of Neuroscience
2003
475
13
Prospects for new restorative and neuroprotective treatments in Parkinson's disease
Nature
1999
442
14
Long-Term rAAV-Mediated Gene Transfer of GDNF in the Rat Parkinson's Model: Intrastriatal But Not Intranigral Transduction Promotes Functional Regeneration in the Lesioned Nigrostriatal System
Journal of Neuroscience
2000
386
15
Nigrostriatal -synucleinopathy induced by viral vector-mediated overexpression of human -synuclein: A new primate model of Parkinson's disease
Proceedings of the National Academy of Sciences of the United States of America
2003
382
16
l-DOPA-Induced Dyskinesia in the Intrastriatal 6-Hydroxydopamine Model of Parkinson's Disease: Relation to Motor and Cellular Parameters of Nigrostriatal Function
Neurobiology of Disease
2002
378
17
Generation of induced neurons via direct conversion in vivo
Proceedings of the National Academy of Sciences of the United States of America
2013
376
18
Isolation of Human Induced Pluripotent Stem Cell-Derived Dopaminergic Progenitors by Cell Sorting for Successful Transplantation
Stem Cell Reports
2014
373
19
Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson’s Disease
Cell Stem Cell
2014
373
20
Genetic control of dorsal-ventral identity in the telencephalon: opposing roles for
Pax6
and
Gsh2
Development (Cambridge)
2000
357
21
Improving the Survival of Grafted Dopaminergic Neurons: A Review over Current Approaches
Cell Transplantation
2000
327
22
Towards a neuroprotective gene therapy for Parkinson’s disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model11Published on the World Wide Web on 10 October 2000.
Brain Research
2000
323
23
Congo red and protein aggregation in neurodegenerative diseases
Brain Research Reviews
2007
323
24
Neural transplantation for the treatment of Parkinson's disease
Lancet Neurology, The
2003
322
25
Plasma fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis.
Nature Medicine
2001
311
26
Acceleration of α-Synuclein Aggregation by Exosomes
Journal of Biological Chemistry
2015
305
27
Effect of Mutant α-Synuclein on Dopamine Homeostasis in a New Human Mesencephalic Cell Line
Journal of Biological Chemistry
2002
297
28
Research in motion: the enigma of Parkinson's disease pathology spread
Nature Reviews Neuroscience
2008
296
29
Mechanisms of neural plasticity following brain injury
Current Opinion in Neurobiology
2006
290
30
Caspase inhibition reduces apoptosis and increases survival of nigral transplants
Nature Medicine
1999
279
31
Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation
Cell Reports
2015
268
32
Localized striatal delivery of GDNF as a treatment for Parkinson disease
Nature Neuroscience
2004
262
33
Impaired neurotransmission caused by overexpression of α-synuclein in nigral dopamine neurons
Proceedings of the National Academy of Sciences of the United States of America
2012
250
34
Cell transplantation in Parkinson's disease: how can we make it work?
Trends in Neurosciences
2005
249
35
Regionalization and fate specification in neurospheres: the role of Olig2 and Pax6
Molecular and Cellular Neurosciences
2004
246
36
Cell-based therapies for Parkinson disease—past insights and future potential
Nature Reviews Neurology
2015
242
37
Studies on Neuroprotective and Regenerative Effects of GDNF in a Partial Lesion Model of Parkinson's Disease
Neurobiology of Disease
1997
239
38
Current trends in stroke rehabilitation. A review with focus on brain plasticity
Acta Neurologica Scandinavica
2011
228
39
Impaired dopamine storage resulting from alpha-synuclein mutations may contribute to the pathogenesis of Parkinson's disease
Human Molecular Genetics
2002
226
40
Optogenetic control of epileptiform activity
Proceedings of the National Academy of Sciences of the United States of America
2009
225
41
Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice
Acta Neuropathologica
2013
224
42
Combined 5-HT1A and 5-HT1B receptor agonists for the treatment of L-DOPA-induced dyskinesia
Brain
2008
223
43
Neuronal Plasticity and Dendritic Spines: Effect of Environmental Enrichment on Intact and Postischemic Rat Brain
Journal of Cerebral Blood Flow and Metabolism
2002
222
44
Progressive neurodegenerative and behavioural changes induced by AAV-mediated overexpression of α-synuclein in midbrain dopamine neurons
Neurobiology of Disease
2012
222
45
Neuroprotective Effects of a Novel Nitrone, NXY-059, after Transient Focal Cerebral Ischemia in the Rat
Journal of Cerebral Blood Flow and Metabolism
1999
221
46
α-Synuclein–Induced Down-Regulation of Nurr1 Disrupts GDNF Signaling in Nigral Dopamine Neurons
Science Translational Medicine
2012
221
47
Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the lateral ventricle
European Journal of Neuroscience
1999
219
48
Alpha-Synuclein Cell-to-Cell Transfer and Seeding in Grafted Dopaminergic Neurons In Vivo
PLoS ONE
2012
218
49
Alpha‐synuclein transfers from neurons to oligodendrocytes
Glia
2014
215
50
Identification of Dopaminergic Neurons of Nigral and Ventral Tegmental Area Subtypes in Grafts of Fetal Ventral Mesencephalon Based on Cell Morphology, Protein Expression, and Efferent Projections
Journal of Neuroscience
2005
212
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