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Top Articles

#TitleJournalYearCitations
1Tertiary lymphoid structures improve immunotherapy and survival in melanomaNature20201,209
2An African origin for the intimate association between humans and Helicobacter pyloriNature2007826
3The Human Protein Atlas—a tool for pathologyJournal of Pathology2008792
4Prostate-specific antigen and prostate cancer: prediction, detection and monitoringNature Reviews Cancer2008713
5Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotypeCancer Cell2006624
6Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein MProceedings of the National Academy of Sciences of the United States of America2011512
7Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencingNature Communications2018496
8Half-lives of PFOS, PFHxS and PFOA after end of exposure to contaminated drinking waterOccupational and Environmental Medicine2018458
9YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue RegenerationCell Stem Cell2018447
10Neutrophil Extracellular Traps That Are Not Degraded in Systemic Lupus Erythematosus Activate Complement Exacerbating the DiseaseJournal of Immunology2012425
11Caspase 8 inhibits programmed necrosis by processing CYLDNature Cell Biology2011409
12Inducing physiological stress recovery with sounds of nature in a virtual reality forest — Results from a pilot studyPhysiology and Behavior2013407
13Regulation of Stem Cell Pluripotency and Differentiation Involves a Mutual Regulatory Circuit of the Nanog, OCT4, and SOX2 Pluripotency Transcription Factors With Polycomb Repressive Complexes and Stem Cell microRNAsStem Cells and Development2009375
14Plasminogen Is a Critical Host Pathogenicity Factor for Group A Streptococcal InfectionScience2004365
15Symbionts as Major Modulators of Insect Health: Lactic Acid Bacteria and HoneybeesPLoS ONE2012363
16Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell–stimulating programs in basophilsNature Immunology2009362
17Epidemiology of Severe Streptococcus pyogenes Disease in EuropeJournal of Clinical Microbiology2008356
18Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotypeProceedings of the National Academy of Sciences of the United States of America2002349
19Conversion of Acetaminophen to the Bioactive N-Acylphenolamine AM404 via Fatty Acid Amide Hydrolase-dependent Arachidonic Acid Conjugation in the Nervous SystemJournal of Biological Chemistry2005347
20Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem CellsCell2018332
21Gas6 and protein SFEBS Journal2006316
22Transancestral mapping and genetic load in systemic lupus erythematosusNature Communications2017314
23Complement activation and inhibition: a delicate balanceTrends in Immunology2009304
24Scavenger receptors: role in innate immunity and microbial pathogenesisCellular Microbiology2009290
25Microfluidic, Label-Free Enrichment of Prostate Cancer Cells in Blood Based on AcoustophoresisAnalytical Chemistry2012287
26Advances in understanding pathogenic mechanisms of thrombophilic disordersBlood2008285
27The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-β Pathway in NeuroblastomaMolecular Cell2010279
28Modeling the Time Evolution of the Nanoparticle-Protein Corona in a Body FluidPLoS ONE2010272
29Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 FamiliesJournal of Clinical Oncology2020270
30Regulation of Blood Coagulation by the Protein C Anticoagulant PathwayArteriosclerosis, Thrombosis, and Vascular Biology2005268
31Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial ActivationCell Reports2015268
32Hypoxia-induced dedifferentiation of tumor cells – A mechanism behind heterogeneity and aggressiveness of solid tumorsSeminars in Cell and Developmental Biology2005262
33Clinical and Microbiological Characteristics of SevereStreptococcus pyogenesDisease in EuropeJournal of Clinical Microbiology2009252
34Complement deficiencies and systemic lupus erythematosusAutoimmunity2007247
35The Potential of MicroRNAs as Prostate Cancer BiomarkersEuropean Urology2016243
36The anticoagulant protein C pathwayFEBS Letters2005239
37Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and METProceedings of the National Academy of Sciences of the United States of America2014232
38Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemiaNature Communications2016225
39Whole-genome sequencing of triple-negative breast cancers in a population-based clinical studyNature Medicine2019218
40WNT5A induces release of exosomes containing pro-angiogenic and immunosuppressive factors from malignant melanoma cellsMolecular Cancer2014213
41Complement deficiency states and associated infectionsMolecular Immunology2011204
42Complement evasion strategies of pathogens—Acquisition of inhibitors and beyondMolecular Immunology2009203
43Toll-Like Receptor 4 Expression and Cytokine Responses in the Human Urinary Tract MucosaInfection and Immunity2004202
44Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironmentsNature Communications2014197
45MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cellsProceedings of the National Academy of Sciences of the United States of America2013194
46Oral status, oral infections and some lifestyle factors as risk factors for oral and oropharyngeal squamous cell carcinoma. A population-based case-control study in southern SwedenActa Oto-Laryngologica2005193
47Strong association between infection with human papillomavirus and oral and oropharyngeal squamous cell carcinoma: A population-based case-control study in southern SwedenActa Oto-Laryngologica2005192
48Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 casesProceedings of the National Academy of Sciences of the United States of America2018192
49A locus on human chromosome 20 contains several genes expressing protease inhibitor domains with homology to whey acidic proteinBiochemical Journal2002190
50Factor V and Thrombotic DiseaseArteriosclerosis, Thrombosis, and Vascular Biology2002188