# | Title | Journal | Year | Citations |
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1 | Mycobacterium paratuberculosis DNA in Crohn's disease tissue. | Gut | 1992 | 340 |
2 | Detection and Verification of Mycobacterium avium subsp. paratuberculosis in Fresh Ileocolonic Mucosal Biopsy Specimens from Individuals with and without Crohn's Disease | Journal of Clinical Microbiology | 2003 | 337 |
3 | Trypsinogen activation peptides assay in the early prediction of severity of acute pancreatitis | Lancet, The | 1990 | 256 |
4 | Polymerase chain reaction detection of Mycobacterium paratuberculosis and Mycobacterium avium subsp silvaticum in long term cultures from Crohn's disease and control tissues. | Gut | 1992 | 173 |
5 | The importance of the resection margin in conservative surgery for breast cancer | European Journal of Surgical Oncology | 1996 | 151 |
6 | Antibiotic use, childhood affluence and irritable bowel syndrome (IBS) | European Journal of Gastroenterology and Hepatology | 1998 | 143 |
7 | Calcium ions and the control of proliferation in normal and cancer cells | Bioscience Reports | 1982 | 132 |
8 | DNA PROBES DEMONSTRATE A SINGLE HIGHLY CONSERVED STRAIN OF MYCOBACTERIUM AVIUM INFECTING AIDS PATIENTS | Lancet, The | 1989 | 121 |
9 | Role of the Neutrophil in Septic Shock and the Adult Respiratory Distress Syndrome | The European Journal of Surgery | 2002 | 118 |
10 | Simvastatin Attenuates the Activity of Matrix Metalloprotease-9 in Aneurysmal Aortic Tissue | European Journal of Vascular and Endovascular Surgery | 2007 | 115 |
11 | The use of DNA probes identifying restriction-fragment-length polymorphisms to examine the Mycobacterium avium complex | Molecular Microbiology | 1987 | 110 |
12 | Characterization of IS900 loci in Mycobacterium avium subsp. paratuberculosis and development of multiplex PCR typing The GenBank accession numbers for the sequences reported in this paper are AJ011838, AJ250015–AJ250023 and AJ251434–AJ251437. | Microbiology (United Kingdom) | 2000 | 103 |
13 | ASSOCIATION OF ULCERATIVE COLITIS WITH MULTIPLE SCLEROSIS | Lancet, The | 1982 | 89 |
14 | IS902, an insertion element of the chronic-enteritis-causing Mycobacterium avium subsp. silvaticum | Journal of General Microbiology | 1992 | 89 |
15 | Specific detection of Mycobacterium paratuberculosis by DNA hybridisation with a fragment of the insertion element IS900. | Gut | 1991 | 76 |
16 | Mycobacterial interspersed repetitive units (MIRU) differentiate Mycobacterium avium subspecies paratuberculosis from other species of the Mycobacterium avium complex | Molecular and Cellular Probes | 2003 | 76 |
17 | The use of Seldi ProteinChip? Arrays to monitor production of Alzheimer's ?-amyloid in transfected cells | Journal of Peptide Science | 2000 | 74 |
18 | Grand Round: Mycobacterium paratuberculosis cervical lymphadenitis, followed five years later by terminal ileitis similar to Crohn's disease | BMJ: British Medical Journal | 1998 | 70 |
19 | PROTAGONIST: Mycobacterium avium subspecies paratuberculosis is a cause of Crohn's disease | Gut | 2001 | 67 |
20 | A 13-year review of jejunoileal bypass | British Journal of Surgery | 2005 | 66 |
21 | Type 1 prophospholipase A2 propeptide in acute lung injury | Lancet, The | 1994 | 55 |
22 | Heat shock proteins induce pores in membranes | Bioscience Reports | 1990 | 51 |
23 | An intra-patient placebo-controlled phase I trial to evaluate the safety and tolerability of intradermal IMM-101 in melanoma | Annals of Oncology | 2012 | 45 |
24 | Studies on the formation of intrachain disulphide bonds in newly biosynthesised bovine prolactin. Role of protein-disulphide isomerase | FEBS Journal | 1985 | 40 |
25 | Determination of Genome Size and DNA Homology between an Unclassified Mycobacterium Species Isolated from Patients with Crohn's Disease and Other Mycobacteria | Microbiology (United Kingdom) | 1987 | 40 |
26 | Quadruple antimycobacterial chemotherapy in Crohn's disease: results at 9 months of a pilot study in 20 patients | Alimentary Pharmacology and Therapeutics | 1989 | 38 |
27 | Membrane specific carbonic anhydrase (CAIV) expression in human tissues | Biochimica Et Biophysica Acta - Biomembranes | 1990 | 37 |
28 | A photoactivatable synthetic transit peptide labels 30 kDa and 52 kDa polypeptides of the chloroplast inner envelope membrane | FEBS Letters | 1988 | 36 |
29 | Electric shock-mediated transfection of cells. Characterization and optimization of electrical parameters | Biochemical Journal | 1988 | 36 |
30 | Investigation of mycobacteria in Crohn's disease tissue by Southern blotting and DNA hybridisation with cloned mycobacterial genomic DNA probes from a Crohn's disease isolated mycobacteria. | Gut | 1988 | 31 |
31 | Alteration of the mechanical properties of sickle cells by repetitive deoxygenation: role of calcium and the effects of calcium blockers | British Journal of Haematology | 1989 | 29 |
32 | Optimisation of Conditions for the Affinity Chromatography of Human Enterokinase on Immobilised p-Aminobenzamidine. Improvement of the Preparative Procedure by Inclusion of Negative Affinity Chromatography with Glycylglycyl-aniline | FEBS Journal | 1978 | 28 |
33 | p43, the protein product of the atypical insertion sequence IS900, is expressed in Mycobacterium paratuberculosis | Journal of General Microbiology | 1992 | 28 |
34 | Treatment with drugs active against Mycobacterium avium subspecies paratuberculosis can heal Crohn's disease: more evidence for a neglected Public Health tragedy | Digestive and Liver Disease | 2002 | 28 |
35 | Mycobacterial diseases of the gut: some impact from molecular biology. | Gut | 1992 | 26 |
36 | Effect of a satiating meal on the concentrations of procolipase propeptide in the serum and urine of normal and morbidly obese subjects. | Gut | 1993 | 26 |
37 | No evidence for antibodies to mycobacterial A60 antigen in Crohn's disease sera by enzyme-linked immunoabsorbent assay (ELISA) | Journal of Medical Microbiology | 1988 | 21 |
38 | Detection of Human Pancreatic Pro-Phospholipase A2 Activation Using an Immunoassay for the Free Activation Peptide DSGISPR | Annals of Clinical Biochemistry | 1991 | 19 |
39 | Isolation and properties of the signal region from ovalbumin | FEBS Letters | 1986 | 18 |
40 | A survey of the available colorimetric indicators for Ca2+ and Mg2+ ions in biological experiments | Cell Calcium | 1983 | 17 |
41 | Activation of Human Granulocyte Type 1-Prophospholipase A2 | Scandinavian Journal of Gastroenterology | 1996 | 17 |
42 | Solid-phase synthesis and cyclization of a large branched peptide from IgG Fc with affinity for FcγRI | | 1999 | 16 |
43 | Successful anaesthesia and small-bowel anastomosis in the guineapig | Laboratory Animals | 1980 | 15 |
44 | Correlation between Doppler flow velocity waveforms and cord blood viscosity | BJOG: an International Journal of Obstetrics and Gynaecology | 1989 | 15 |
45 | Abnormal neutrophil adhesion in sickle cell anaemia and crisis: relationship to blood rheology | British Journal of Haematology | 1991 | 15 |
46 | Maternal blood viscosity and uteroplacental blood flow velocity waveforms in normal and complicated pregnancies | BJOG: an International Journal of Obstetrics and Gynaecology | 1988 | 13 |
47 | The application of molecular techniques to the diagnosis and epidemiology of mycobacterial diseases | Journal of Applied Bacteriology | 1996 | 13 |
48 | A differential effect between the acute and chronic administration of ethanol on the endocytotic rate konstant, ke, for internalisation of asialoglycoproteins by hepatocytes | Biochimica Et Biophysica Acta - Biomembranes | 1986 | 12 |
49 | Antibodies to trypsinogen activation peptides recognize both Ca2+-dependent and Ca2+— independent epitopes | Biochemical Society Transactions | 1988 | 11 |
50 | The gp120 envelope of HIV-1 binds peptides in a similar manner to human leukocyte antigens | Aids | 1995 | 11 |