# | Title | Journal | Year | Citations |
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1 | -Synuclein Blocks ER-Golgi Traffic and Rab1 Rescues Neuron Loss in Parkinson's Models | Science | 2006 | 1,268 |
2 | Hallucinogens | | 2004 | 1,043 |
3 | Sirtuin 2 Inhibitors Rescue -Synuclein-Mediated Toxicity in Models of Parkinson's Disease | Science | 2007 | 995 |
4 | Serotonin Receptors | Chemical Reviews | 2008 | 751 |
5 | Annonaceous Acetogenins: Recent Progress | Journal of Natural Products | 1999 | 741 |
6 | PGC-1 α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease | Science Translational Medicine | 2010 | 691 |
7 | α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity | Nature Genetics | 2009 | 501 |
8 | The Parkinson's disease protein α-synuclein disrupts cellular Rab homeostasis | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 479 |
9 | Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesis | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 425 |
10 | Pharmacological Characterization of 4-hydroxy-N-desmethyl Tamoxifen, a Novel Active Metabolite of Tamoxifen | Breast Cancer Research and Treatment | 2004 | 418 |
11 | Computer-aided drug design platform using PyMOL | Journal of Computer-Aided Molecular Design | 2011 | 416 |
12 | The Use of Biological Assays to Evaluate Botanicals | Drug Information Journal | 1998 | 382 |
13 | Polydopamine-Based Simple and Versatile Surface Modification of Polymeric Nano Drug Carriers | ACS Nano | 2014 | 363 |
14 | β2-Adrenoreceptor is a regulator of the α-synuclein gene driving risk of Parkinson’s disease | Science | 2017 | 341 |
15 | Phosphoproteins in extracellular vesicles as candidate markers for breast cancer | Proceedings of the National Academy of Sciences of the United States of America | 2017 | 328 |
16 | Medicinal Benefits of Green Tea: Part I. Review of Noncancer Health Benefits | Journal of Alternative and Complementary Medicine | 2005 | 301 |
17 | Autophagosomal Membrane Serves as Platform for Intracellular Death-inducing Signaling Complex (iDISC)-mediated Caspase-8 Activation and Apoptosis | Journal of Biological Chemistry | 2012 | 291 |
18 | Acid β‐glucosidase mutants linked to gaucher disease, parkinson disease, and lewy body dementia alter α‐synuclein processing | Annals of Neurology | 2011 | 276 |
19 | Bimolecular fluorescence complementation (BiFC): A 5-year update and future perspectives | BioTechniques | 2012 | 245 |
20 | Enhanced Cancer Immunotherapy by Chimeric Antigen Receptor–Modified T Cells Engineered to Secrete Checkpoint Inhibitors | Clinical Cancer Research | 2017 | 238 |
21 | Paw Paw and Cancer: Annonaceous Acetogenins from Discovery to Commercial Products | Journal of Natural Products | 2008 | 237 |
22 | Yeast Reveal a “Druggable” Rsp5/Nedd4 Network that Ameliorates α-Synuclein Toxicity in Neurons | Science | 2013 | 234 |
23 | Dissolution and Precipitation Behavior of Amorphous Solid Dispersions | Journal of Pharmaceutical Sciences | 2011 | 231 |
24 | Design and Synthesis of [111In]DTPA−Folate for Use as a Tumor-Targeted Radiopharmaceutical | Bioconjugate Chemistry | 1997 | 199 |
25 | Serotonergic basis of antipsychotic drug effects in schizophrenia | Biological Psychiatry | 1998 | 199 |
26 | Getting Syk: spleen tyrosine kinase as a therapeutic target | Trends in Pharmacological Sciences | 2014 | 195 |
27 | Molecular Interaction of Serotonin 5-HT2A Receptor Residues Phe339(6.51) and Phe340(6.52) with Superpotent N-Benzyl Phenethylamine Agonists | Molecular Pharmacology | 2006 | 194 |
28 | A convenient one-pot synthesis of 2-substituted benzimidazoles | Journal of Molecular Catalysis A | 2006 | 189 |
29 | An improved bimolecular fluorescence complementation assay with a high signal-to-noise ratio | BioTechniques | 2010 | 181 |
30 | Quinone Reductase Induction as a Biomarker for Cancer Chemoprevention⊥ | Journal of Natural Products | 2006 | 180 |
31 | Small heat shock proteins protect against α-synuclein-induced toxicity and aggregation | Biochemical and Biophysical Research Communications | 2006 | 180 |
32 | Interaction of Cyanide and Nitric Oxide with Cytochrome c Oxidase: Implications for Acute Cyanide Toxicity | Toxicological Sciences | 2008 | 178 |
33 | Selective Synthesis and Biological Evaluation of Sulfate-Conjugated Resveratrol Metabolites | Journal of Medicinal Chemistry | 2010 | 178 |
34 | Measuring nanoscale viscoelastic parameters of cells directly from AFM force-displacement curves | Scientific Reports | 2017 | 174 |
35 | Magnetic sensitivity of cryptochrome 4 from a migratory songbird | Nature | 2021 | 171 |
36 | Neuroprotective effects of anthocyanin- and proanthocyanidin-rich extracts in cellular models of Parkinson׳s disease | Brain Research | 2014 | 167 |
37 | Medicinal Benefits of Green Tea: Part II. Review of Anticancer Properties | Journal of Alternative and Complementary Medicine | 2005 | 159 |
38 | Long-chain carboxychromanols, metabolites of vitamin E, are potent inhibitors of cyclooxygenases | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 159 |
39 | Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson’s disease models | DMM Disease Models and Mechanisms | 2010 | 159 |
40 | Androgen Receptor Splice Variants Dimerize to Transactivate Target Genes | Cancer Research | 2015 | 158 |
41 | Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes | Journal of Biological Chemistry | 2018 | 158 |
42 | 2-Bromopalmitate and 2-(2-hydroxy-5-nitro-benzylidene)-benzo[b]thiophen-3-one inhibit DHHC-mediated palmitoylation in vitro | Journal of Lipid Research | 2009 | 157 |
43 | Synthesis of New Indeno[1,2-c]isoquinolines: Cytotoxic Non-Camptothecin Topoisomerase I Inhibitors | Journal of Medicinal Chemistry | 2000 | 154 |
44 | Structure−Activity Relationships of Diverse Annonaceous Acetogenins against Multidrug Resistant Human Mammary Adenocarcinoma (MCF-7/Adr) Cells | Journal of Medicinal Chemistry | 1997 | 153 |
45 | A Physical Interaction Network of Dengue Virus and Human Proteins | Molecular and Cellular Proteomics | 2011 | 153 |
46 | STAT3 and epithelial–mesenchymal transitions in carcinomas | Jak-stat | 2014 | 151 |
47 | An efficient one-pot synthesis of polyhydroquinoline derivatives through the Hantzsch four component condensation | Journal of Molecular Catalysis A | 2006 | 150 |
48 | Cleavage of Carbon−Carbon Bonds through the Mild Release of Trifluoroacetate: Generation of α,α-Difluoroenolates for Aldol Reactions | Journal of the American Chemical Society | 2011 | 148 |
49 | Intestinal peptide transport systems and oral drug availability | Pharmaceutical Research | 1999 | 146 |
50 | Immobilized Artificial Membranes — screens for drug membrane interactions | Advanced Drug Delivery Reviews | 1997 | 142 |