The unfolded protein response: from stress pathway to homeostatic regulation | Science | 2011 | 3.7K |
Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy | Nature Medicine | 2011 | 988 |
Ciliogenesis: building the cell's antenna | Nature Reviews Molecular Cell Biology | 2011 | 679 |
Molecular control of endothelial cell behaviour during blood vessel morphogenesis | Nature Reviews Molecular Cell Biology | 2011 | 676 |
X-ray emission spectroscopy evidences a central carbon in the nitrogenase iron-molybdenum cofactor | Science | 2011 | 659 |
Robust multicellular computing using genetically encoded NOR gates and chemical 'wires' | Nature | 2011 | 606 |
SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome | Molecular Cell | 2011 | 568 |
Global landscape of HIV-human protein complexes | Nature | 2011 | 507 |
Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response | Science | 2011 | 477 |
A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition | Nature Genetics | 2011 | 461 |
Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways | Cell | 2011 | 435 |
Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein | Journal of Biological Chemistry | 2011 | 423 |
Accessing protein conformational ensembles using room-temperature X-ray crystallography | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 395 |
Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration | Cell | 2011 | 365 |
Microtubule nucleation by γ-tubulin complexes | Nature Reviews Molecular Cell Biology | 2011 | 363 |
Phosphatidylcholine synthesis for lipid droplet expansion is mediated by localized activation of CTP:phosphocholine cytidylyltransferase | Cell Metabolism | 2011 | 319 |
Chemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparum | PLoS Biology | 2011 | 296 |
Intensive meditation training, immune cell telomerase activity, and psychological mediators | Psychoneuroendocrinology | 2011 | 288 |
Temporal analysis of the honey bee microbiome reveals four novel viruses and seasonal prevalence of known viruses, Nosema, and Crithidia | PLoS ONE | 2011 | 287 |
Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 279 |
The conserved GTPase Gem1 regulates endoplasmic reticulum-mitochondria connections | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 268 |
Impartial comparative analysis of measurement of leukocyte telomere length/DNA content by Southern blots and qPCR | Nucleic Acids Research | 2011 | 263 |
Conformational dynamics of the molecular chaperone Hsp90 | Quarterly Reviews of Biophysics | 2011 | 225 |
Cumulative inflammatory load is associated with short leukocyte telomere length in the Health, Aging and Body Composition Study | PLoS ONE | 2011 | 218 |
Chromodomain-mediated oligomerization of HP1 suggests a nucleosome-bridging mechanism for heterochromatin assembly | Molecular Cell | 2011 | 214 |