Role of accurate mass measurement (+/- 10 ppm) in protein identification strategies employing MS or MS/MS and database searching | Analytical Chemistry | 1999 | 997 |
Effects of angiogenesis inhibitors on multistage carcinogenesis in mice | Science | 1999 | 866 |
Signals from the reproductive system regulate the lifespan of C. elegans | Nature | 1999 | 716 |
Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14 | Nature | 1999 | 714 |
The maximal affinity of ligands | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 709 |
A structural change in the kinesin motor protein that drives motility | Nature | 1999 | 652 |
A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor | Nature | 1999 | 592 |
Kin I kinesins are microtubule-destabilizing enzymes | Cell | 1999 | 584 |
Copper binding to the prion protein: structural implications of four identical cooperative binding sites | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 485 |
Cytonemes: cellular processes that project to the principal signaling center in Drosophila imaginal discs | Cell | 1999 | 477 |
Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 451 |
Regulation of lifespan by sensory perception in Caenorhabditis elegans | Nature | 1999 | 428 |
Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel | Journal of Molecular Biology | 1999 | 428 |
Growth-cone attraction to netrin-1 is converted to repulsion by laminin-1 | Nature | 1999 | 426 |
Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice | Genes and Development | 1999 | 388 |
A comparison between the sulfhydryl reductants tris(2-carboxyethyl)phosphine and dithiothreitol for use in protein biochemistry | Analytical Biochemistry | 1999 | 367 |
Gata5 is required for the development of the heart and endoderm in zebrafish | Genes and Development | 1999 | 354 |
I5M: 3D widefield light microscopy with better than 100 nm axial resolution | Journal of Microscopy | 1999 | 337 |
Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae | Molecular Biology of the Cell | 1999 | 328 |
Identification of a mating type-like locus in the asexual pathogenic yeast Candida albicans | Science | 1999 | 322 |
High-resolution X-ray structure of an early intermediate in the bacteriorhodopsin photocycle | Nature | 1999 | 302 |
Immunohistochemical localization of GABA(B) receptors in the rat central nervous system | Journal of Comparative Neurology | 1999 | 283 |
Regulation of nuclear localization: a key to a door | Annual Review of Cell and Developmental Biology | 1999 | 267 |
Genes regulating dendritic outgrowth, branching, and routing in Drosophila | Genes and Development | 1999 | 267 |
Roles of phosphorylation sites in regulating activity of the transcription factor Pho4 | Science | 1999 | 263 |