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Top Articles

#TitleJournalYearCitations
1Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2Nature Biotechnology201911,167
2Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Autophagy20164,701
3Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genomeCell19821,683
4Up on the tightrope: natural killer cell activation and inhibitionNature Immunology20081,425
5A chemokine-driven positive feedback loop organizes lymphoid folliclesNature20001,103
6Exportin 1 (Crm1p) Is an Essential Nuclear Export FactorCell19971,067
7Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibitionNature20171,043
8Chemokines and Cell Migration in Secondary Lymphoid OrgansScience1999964
9NK cells and cancer: you can teach innate cells new tricksNature Reviews Cancer2016903
10Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cellsNature Immunology2007809
11The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagenNature Medicine2000755
12A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1Nature1998751
13Lymphocyte Sequestration Through S1P Lyase Inhibition and Disruption of S1P GradientsScience2005732
14Quasispecies Theory and the Behavior of RNA VirusesPLoS Pathogens2010717
15The integrin αvβ8 mediates epithelial homeostasis through MT1-MMP–dependent activation of TGF-β1Journal of Cell Biology2002657
16Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5Nature Immunology2004649
17Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifsCell1990646
18Chemokines as regulators of T cell differentiationNature Immunology2001643
19Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicityNature Genetics2010632
20Heat shock factor and the heat shock responseCell1991608
21A transmembrane CXC chemokine is a ligand for HIV-coreceptor BonzoNature Immunology2000603
22A Coordinated Change in Chemokine Responsiveness Guides Plasma Cell MovementsJournal of Experimental Medicine2001589
23Conditional deletion of Gata3 shows its essential function in TH1-TH2 responsesNature Immunology2004572
24Nucleotide sequence of the retroviral leukemia gene v-myb and its cellular progenitor c-myb: The architecture of a transduced oncogeneCell1982568
25Direct activation of the serine/threonine kinase activity of raf-1 through tyrosine phosphorylation by the PDGF β-receptorCell1989552
26Strains and Strategies for Large-Scale Gene Deletion Studies of the Diploid Human Fungal Pathogen Candida albicansEukaryotic Cell2005530
27Lymphotoxin α/β and Tumor Necrosis Factor Are Required for Stromal Cell Expression of Homing Chemokines in B and T Cell Areas of the SpleenJournal of Experimental Medicine1999529
28Control of Filament Formation inCandida albicansby the Transcriptional Repressor TUP1Science1997524
29The RNA silencing endonuclease Argonaute 2 mediates specific antiviral immunity in Drosophila melanogasterGenes and Development2006511
30NKG2D Receptor and Its Ligands in Host DefenseCancer Immunology Research2015508
31Balanced responsiveness to chemoattractants from adjacent zones determines B-cell positionNature2002506
32A binding site for the T-cell co-receptor CD8 on the α3 domain of HLA-A2Nature1990504
33Identification of a Novel Gammaretrovirus in Prostate Tumors of Patients Homozygous for R462Q RNASEL VariantPLoS Pathogens2006504
34Chemokine Requirements for B Cell Entry to Lymph Nodes and Peyer's PatchesJournal of Experimental Medicine2002479
35Differing Activities of Homeostatic Chemokines CCL19, CCL21, and CXCL12 in Lymphocyte and Dendritic Cell Recruitment and Lymphoid NeogenesisJournal of Immunology2002475
36The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencingNature Cell Biology2006470
37Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipientsNature Biotechnology2019470
38Epigenetic Modification and Antibody-Dependent Expansion of Memory-like NK Cells in Human Cytomegalovirus-Infected IndividualsImmunity2015469
39Construction and Analysis of Two Genome-Scale Deletion Libraries for Bacillus subtilisCell Systems2017457
40Transcripts from the Cellular Homologs of Retroviral Oncogenes: Distribution Among Chicken TissuesMolecular and Cellular Biology1982454
41Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destructionNature Medicine1997453
42In Vivo–Activated Cd4 T Cells Upregulate Cxc Chemokine Receptor 5 and Reprogram Their Response to Lymphoid ChemokinesJournal of Experimental Medicine1999432
43Effect of NKG2D ligand expression on host immune responsesImmunological Reviews2010431
44Epstein-Barr Virus–induced Molecule 1 Ligand Chemokine Is Expressed by Dendritic Cells in Lymphoid Tissues and Strongly Attracts Naive T Cells and Activated B CellsJournal of Experimental Medicine1998430
45Comprehensive Functional Analysis of Mycobacterium tuberculosis Toxin-Antitoxin Systems: Implications for Pathogenesis, Stress Responses, and EvolutionPLoS Genetics2009430
46Requirement for association of p56lck with CD4 in antigen-specific signal transduction in T cellsCell1991424
47Injured sensory neuron–derived CSF1 induces microglial proliferation and DAP12-dependent painNature Neuroscience2016421
48A Phenotypic Profile of the Candida albicans Regulatory NetworkPLoS Genetics2009409
49Analysis of avian leukosis virus DNA and RNA in bursal tumors: Viral gene expression is not required for maintenance of the tumor stateCell1981403
50Evolutionary struggles between NK cells and virusesNature Reviews Immunology2008399