| The unfolded protein response: from stress pathway to homeostatic regulation | Science | 2011 | 3.7K |
| Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy | Nature Medicine | 2011 | 988 |
| Ciliogenesis: building the cell's antenna | Nature Reviews Molecular Cell Biology | 2011 | 679 |
| Molecular control of endothelial cell behaviour during blood vessel morphogenesis | Nature Reviews Molecular Cell Biology | 2011 | 676 |
| X-ray emission spectroscopy evidences a central carbon in the nitrogenase iron-molybdenum cofactor | Science | 2011 | 659 |
| Robust multicellular computing using genetically encoded NOR gates and chemical 'wires' | Nature | 2011 | 606 |
| SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome | Molecular Cell | 2011 | 568 |
| Global landscape of HIV-human protein complexes | Nature | 2011 | 507 |
| Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response | Science | 2011 | 477 |
| Road to ruin: targeting proteins for degradation in the endoplasmic reticulum | Science | 2011 | 476 |
| A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition | Nature Genetics | 2011 | 461 |
| Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways | Cell | 2011 | 435 |
| Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein | Journal of Biological Chemistry | 2011 | 423 |
| Accessing protein conformational ensembles using room-temperature X-ray crystallography | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 395 |
| Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration | Cell | 2011 | 365 |
| Microtubule nucleation by γ-tubulin complexes | Nature Reviews Molecular Cell Biology | 2011 | 363 |
| Phosphatidylcholine synthesis for lipid droplet expansion is mediated by localized activation of CTP:phosphocholine cytidylyltransferase | Cell Metabolism | 2011 | 319 |
| Chemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparum | PLoS Biology | 2011 | 296 |
| Intensive meditation training, immune cell telomerase activity, and psychological mediators | Psychoneuroendocrinology | 2011 | 288 |
| Temporal analysis of the honey bee microbiome reveals four novel viruses and seasonal prevalence of known viruses, Nosema, and Crithidia | PLoS ONE | 2011 | 287 |
| Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 279 |
| The conserved GTPase Gem1 regulates endoplasmic reticulum-mitochondria connections | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 268 |
| Impartial comparative analysis of measurement of leukocyte telomere length/DNA content by Southern blots and qPCR | Nucleic Acids Research | 2011 | 263 |
| ModBase, a database of annotated comparative protein structure models, and associated resources | Nucleic Acids Research | 2011 | 252 |
| Conformational dynamics of the molecular chaperone Hsp90 | Quarterly Reviews of Biophysics | 2011 | 225 |
