# | Title | Journal | Year | Citations |
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1 | New functions for the matrix metalloproteinases in cancer progression | Nature Reviews Cancer | 2002 | 5,365 |
2 | Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer. | Proceedings of the National Academy of Sciences of the United States of America | 1988 | 4,652 |
3 | Pericytes are required for blood–brain barrier integrity during embryogenesis | Nature | 2010 | 1,675 |
4 | Roles of the immune system in cancer: from tumor initiation to metastatic progression | Genes and Development | 2018 | 1,326 |
5 | Transcriptional Activators of TGF-β Responses: Smads | Cell | 1998 | 1,034 |
6 | Mechanisms of adverse effects of anti-VEGF therapy for cancer | British Journal of Cancer | 2007 | 865 |
7 | Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice | Nature Medicine | 2014 | 858 |
8 | Rapid vascular regrowth in tumors after reversal of VEGF inhibition | Journal of Clinical Investigation | 2006 | 709 |
9 | From cells to organs: building polarized tissue | Nature Reviews Molecular Cell Biology | 2008 | 695 |
10 | Guidelines on nicotine dose selection for in vivo research | Psychopharmacology | 2007 | 694 |
11 | Midbrain development induced by FGF8 in the chick embryo | Nature | 1996 | 691 |
12 | Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse | Development (Cambridge) | 1992 | 613 |
13 | The many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasis | Trends in Cell Biology | 2001 | 612 |
14 | The blood–brain barrier in health and disease | Annals of Neurology | 2012 | 592 |
15 | Circulating Tumor Cells | Science | 2013 | 591 |
16 | cAMP-Dependent Growth Cone Guidance by Netrin-1 | Neuron | 1997 | 542 |
17 | Matrix Metalloproteinase 9 and Vascular Endothelial Growth Factor Are Essential for Osteoclast Recruitment into Developing Long Bones | Journal of Cell Biology | 2000 | 537 |
18 | Cloning of a lymphocyte homing receptor reveals a lectin domain | Cell | 1989 | 532 |
19 | A molecular network for de novo generation of the apical surface and lumen | Nature Cell Biology | 2010 | 529 |
20 | Intraneuronal substance P contributes to the severity of experimental arthritis | Science | 1984 | 507 |
21 | The Mouse Blood-Brain Barrier Transcriptome: A New Resource for Understanding the Development and Function of Brain Endothelial Cells | PLoS ONE | 2010 | 481 |
22 | ECM signalling: orchestrating cell behaviour and misbehaviour | Trends in Cell Biology | 1998 | 473 |
23 | Injured sensory neuron–derived CSF1 induces microglial proliferation and DAP12-dependent pain | Nature Neuroscience | 2016 | 421 |
24 | MULTI-seq: sample multiplexing for single-cell RNA sequencing using lipid-tagged indices | Nature Methods | 2019 | 421 |
25 | TGFβ biology in cancer progression and immunotherapy | Nature Reviews Clinical Oncology | 2021 | 420 |
26 | NMDA-receptor regulation of substance P release from primary afferent nociceptors | Nature | 1997 | 408 |
27 | Hormonal, cellular, and molecular control of prostatic development | Developmental Biology | 2003 | 396 |
28 | Association of Rab25 and Rab11a with the Apical Recycling System of Polarized Madin–Darby Canine Kidney Cells | Molecular Biology of the Cell | 1999 | 381 |
29 | β2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis | Nature Medicine | 2015 | 373 |
30 | FGF-4 and BMP-2 have opposite effects on limb growth | Nature | 1993 | 371 |
31 | Receptor-mediated transcytosis of IgA in MDCK cells is via apical recycling endosomes. | Journal of Cell Biology | 1994 | 369 |
32 | The Polymeric Immunoglobulin Receptor Translocates Pneumococci across Human Nasopharyngeal Epithelial Cells | Cell | 2000 | 365 |
33 | Methylation of the Hprt gene on the inactive X occurs after chromosome inactivation | Cell | 1987 | 359 |
34 | Matrix remodeling during endochondral ossification | Trends in Cell Biology | 2004 | 355 |
35 | Suppression of Tumor Invasion and Metastasis by Concurrent Inhibition of c-Met and VEGF Signaling in Pancreatic Neuroendocrine Tumors | Cancer Discovery | 2012 | 354 |
36 | Development of a Method for the Purification and Culture of Rodent Astrocytes | Neuron | 2011 | 341 |
37 | En-1 and En-2, two mouse genes with sequence homology to the Drosophila engrailed gene: expression during embryogenesis. | Genes and Development | 1987 | 330 |
38 | Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation | Journal of Clinical Investigation | 2005 | 326 |
39 | Human placental cytotrophoblasts produce the immunosuppressive cytokine interleukin 10. | Journal of Experimental Medicine | 1996 | 317 |
40 | β1-Integrin Orients Epithelial Polarity via Rac1 and Laminin | Molecular Biology of the Cell | 2005 | 317 |
41 | The future of ageing | Nature | 2000 | 315 |
42 | Nuclear Aggregation of Olfactory Receptor Genes Governs Their Monogenic Expression | Cell | 2012 | 315 |
43 | Oligodendrocyte-Encoded HIF Function Couples Postnatal Myelination and White Matter Angiogenesis | Cell | 2014 | 314 |
44 | Anatomical study of the final common pathway for vocalization in the cat | Journal of Comparative Neurology | 1989 | 305 |
45 | An autonomous signal for basolateral sorting in the cytoplasmic domain of the polymeric immunoglobulin receptor | Cell | 1991 | 303 |
46 | Analgesia and hyperalgesia from GABA-mediated modulation of the cerebral cortex | Nature | 2003 | 302 |
47 | The metalloprotease Kuzbanian (ADAM10) mediates the transactivation of EGF receptor by G protein–coupled receptors | Journal of Cell Biology | 2002 | 299 |
48 | A human brain vascular atlas reveals diverse mediators of Alzheimer’s risk | Nature | 2022 | 294 |
49 | The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function | Current Biology | 1997 | 289 |
50 | Dopamine modulates acute responses to cocaine, nicotine and ethanol in Drosophila | Current Biology | 2000 | 288 |