| # | Title | Journal | Year | Citations |
|---|
| 1 | Synaptic, transcriptional and chromatin genes disrupted in autism | Nature | 2014 | 2,254 |
| 2 | Model of autism: increased ratio of excitation/inhibition in key neural systems | Genes, Brain and Behavior | 2003 | 2,198 |
| 3 | Childhood traumas: an outline and overview | American Journal of Psychiatry | 1991 | 1,605 |
| 4 | Interneuron Migration from Basal Forebrain to Neocortex: Dependence on Dlx Genes | Science | 1997 | 1,393 |
| 5 | Galectins. Structure and function of a large family of animal lectins. | Journal of Biological Chemistry | 1994 | 1,294 |
| 6 | Stress, eating and the reward system | Physiology and Behavior | 2007 | 1,274 |
| 7 | Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci | Neuron | 2015 | 1,219 |
| 8 | Cortical Excitatory Neurons and Glia, But Not GABAergic Neurons, Are Produced in the Emx1-Expressing Lineage | Journal of Neuroscience | 2002 | 1,173 |
| 9 | Common variants on chromosome 6p22.1 are associated with schizophrenia | Nature | 2009 | 1,063 |
| 10 | Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus | Neuron | 1992 | 1,029 |
| 11 | Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials | Lancet Respiratory Medicine,the | 2014 | 992 |
| 12 | A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis | Nature Genetics | 1998 | 968 |
| 13 | Mapping genomic loci implicates genes and synaptic biology in schizophrenia | Nature | 2022 | 929 |
| 14 | Pallial and subpallial derivatives in the embryonic chick and mouse telencephalon, traced by the expression of the genes Dlx-2, Emx-1, Nkx-2.1, Pax-6, and Tbr-1 | Journal of Comparative Neurology | 2000 | 925 |
| 15 | Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects | Nature Genetics | 2017 | 838 |
| 16 | NMDA-receptor-dependent synaptic plasticity: multiple forms and mechanisms | Trends in Neurosciences | 1993 | 820 |
| 17 | Pharmacological Treatment of Neuropsychiatric Symptoms of Dementia | JAMA - Journal of the American Medical Association | 2005 | 803 |
| 18 | Socioeconomic Inequalities in Health | JAMA - Journal of the American Medical Association | 1993 | 786 |
| 19 | Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum | Development (Cambridge) | 1999 | 761 |
| 20 | Forebrain gene expression domains and the evolving prosomeric model | Trends in Neurosciences | 2003 | 679 |
| 21 | Measurement of dissociative states with the Clinician-Administered Dissociative States Scale (CADSS) | Journal of Traumatic Stress | 1998 | 667 |
| 22 | Radiation hybrid mapping: a somatic cell genetic method for constructing high-resolution maps of mammalian chromosomes | Science | 1990 | 657 |
| 23 | De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies | Science | 2015 | 646 |
| 24 | A critical period for long-term potentiation at thalamocortical synapses | Nature | 1995 | 644 |
| 25 | SFARI Gene 2.0: a community-driven knowledgebase for the autism spectrum disorders (ASDs) | Molecular Autism | 2013 | 632 |
| 26 | Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands | Nature Genetics | 2017 | 624 |
| 27 | Neurobiological and neuropsychiatric effects of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS) | Frontiers in Neuroendocrinology | 2009 | 600 |
| 28 | Synaptic plasticity in the hippocampus: LTP and LTD | Cell | 1994 | 596 |
| 29 | Using the patient health questionnaire-9 to measure depression among racially and ethnically diverse primary care patients | Journal of General Internal Medicine | 2006 | 558 |
| 30 | Autistic-like behaviour in Scn1a+/− mice and rescue by enhanced GABA-mediated neurotransmission | Nature | 2012 | 543 |
| 31 | Excitation-inhibition balance as a framework for investigating mechanisms in neuropsychiatric disorders | Molecular Psychiatry | 2019 | 531 |
| 32 | Post-traumatic stress disorder | Nature Reviews Disease Primers | 2015 | 529 |
| 33 | What five decades of research tells us about the effects of youth psychological therapy: A multilevel meta-analysis and implications for science and practice. | American Psychologist | 2017 | 524 |
| 34 | Mutations of the Homeobox Genes Dlx-1 and Dlx-2 Disrupt the Striatal Subventricular Zone and Differentiation of Late Born Striatal Neurons | Neuron | 1997 | 520 |
| 35 | Atypical Antipsychotic Augmentation in Major Depressive Disorder: A Meta-Analysis of Placebo-Controlled Randomized Trials | American Journal of Psychiatry | 2009 | 494 |
| 36 | More than a feeling: A unified view of stress measurement for population science | Frontiers in Neuroendocrinology | 2018 | 490 |
| 37 | Serotonin regulates pancreatic beta cell mass during pregnancy | Nature Medicine | 2010 | 489 |
| 38 | Mice lacking Dlx1 show subtype-specific loss of interneurons, reduced inhibition and epilepsy | Nature Neuroscience | 2005 | 458 |
| 39 | Developmental functions of theDistal-less/Dlx homeobox genes | Development (Cambridge) | 2002 | 458 |
| 40 | New insights into sympathetic regulation of glucose and fat metabolism | Diabetologia | 2000 | 456 |
| 41 | Role of the Dlx Homeobox Genes in Proximodistal Patterning of the Branchial Arches: Mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 Alter Morphogenesis of Proximal Skeletal and Soft Tissue Structures Derived from the First and Second Arches | Developmental Biology | 1997 | 440 |
| 42 | Enhancing studies of the connectome in autism using the autism brain imaging data exchange II | Scientific Data | 2017 | 422 |
| 43 | Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development | Science | 2018 | 422 |
| 44 | Sex and gender differences in autism spectrum disorder: summarizing evidence gaps and identifying emerging areas of priority | Molecular Autism | 2015 | 413 |
| 45 | SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors | Nature Cell Biology | 2011 | 408 |
| 46 | Autism as a disorder of neural information processing: directions for research and targets for therapy | Molecular Psychiatry | 2004 | 407 |
| 47 | Agonists at metabotropic glutamate receptors presynaptically inhibit EPSCs in neonatal rat hippocampus. | Journal of Physiology | 1991 | 400 |
| 48 | Children's Adjustment in Conflicted Marriage and Divorce: A Decade Review of Research | Journal of the American Academy of Child and Adolescent Psychiatry | 2000 | 395 |
| 49 | The influence of prior synaptic activity on the induction of long-term potentiation | Science | 1992 | 393 |
| 50 | Cell aging in relation to stress arousal and cardiovascular disease risk factors | Psychoneuroendocrinology | 2006 | 391 |
