| # | Title | Journal | Year | Citations |
|---|
| 1 | Genetics of rheumatoid arthritis contributes to biology and drug discovery | Nature | 2014 | 1,974 |
| 2 | ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR ζ chain | Cell | 1992 | 1,029 |
| 3 | Characteristics associated with hospitalisation for COVID-19 in people with rheumatic disease: data from the COVID-19 Global Rheumatology Alliance physician-reported registry | Annals of the Rheumatic Diseases | 2020 | 908 |
| 4 | Potential Biases in Machine Learning Algorithms Using Electronic Health Record Data | JAMA Internal Medicine | 2018 | 693 |
| 5 | Kappa–opioids produce significantly greater analgesia in women than in men | Nature Medicine | 1996 | 462 |
| 6 | Athletics and Osteoarthritis | American Journal of Sports Medicine | 1997 | 352 |
| 7 | A Genomewide Screen in Multiplex Rheumatoid Arthritis Families Suggests Genetic Overlap with Other Autoimmune Diseases | American Journal of Human Genetics | 2001 | 338 |
| 8 | Insights into the initiation of TCR signaling | Nature Immunology | 2014 | 307 |
| 9 | Reduced B lymphocyte and immunoglobulin levels after atacicept treatment in patients with systemic lupus erythematosus: Results of a multicenter, phase ib, double‐blind, placebo‐controlled, dose‐escalating trial | Arthritis and Rheumatism | 2007 | 278 |
| 10 | Mechanical and biochemical changes in the superficial zone of articular cartilage in canine experimental osteoarthritis | Journal of Orthopaedic Research | 1994 | 276 |
| 11 | The immunological synapse and CD28-CD80 interactions | Nature Immunology | 2001 | 276 |
| 12 | Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with Systemic Lupus Erythematosus | PLoS Genetics | 2011 | 252 |
| 13 | Suppression of Disease in New Zealand Black/New Zealand White Lupus-Prone Mice by Adoptive Transfer of Ex Vivo Expanded Regulatory T Cells | Journal of Immunology | 2006 | 231 |
| 14 | Efficacy and safety of atacicept for prevention of flares in patients with moderate-to-severe systemic lupus erythematosus (SLE): 52-week data (APRIL-SLE randomised trial) | Annals of the Rheumatic Diseases | 2015 | 231 |
| 15 | ASAS-EULAR recommendations for the management of axial spondyloarthritis: 2022 update | Annals of the Rheumatic Diseases | 2023 | 212 |
| 16 | Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease | Nature | 2020 | 198 |
| 17 | Causalgia and reflex sympathetic dystrophy: Does the sympathetic nervous system contribute to the generation of pain? | | 1999 | 184 |
| 18 | THE SCIENCE AND THERAPY OF GLUCOCORTICOID-INDUCED BONE LOSS | Endocrinology and Metabolism Clinics of North America | 1998 | 174 |
| 19 | Rheumatic disease and COVID-19: initial data from the COVID-19 Global Rheumatology Alliance provider registries | Lancet Rheumatology, The | 2020 | 172 |
| 20 | Alternative Therapies Among Adults With a Reported Diagnosis of Asthma or Rhinosinusitis | Chest | 2001 | 170 |
| 21 | Association of mild acetabular dysplasia with an increased risk of incident hip osteoarthritis in elderly white women: The study of osteoporotic fractures | Arthritis and Rheumatism | 2000 | 155 |
| 22 | Primary Sjögren's syndrome as a systemic disease: A study of participants enrolled in an International Sjögren's syndrome registry | Arthritis Care and Research | 2012 | 154 |
| 23 | Associations of baseline use of biologic or targeted synthetic DMARDs with COVID-19 severity in rheumatoid arthritis: Results from the COVID-19 Global Rheumatology Alliance physician registry | Annals of the Rheumatic Diseases | 2021 | 151 |
| 24 | Genome-Wide Association Study and Gene Expression Analysis Identifies CD84 as a Predictor of Response to Etanercept Therapy in Rheumatoid Arthritis | PLoS Genetics | 2013 | 146 |
| 25 | Secondary T cell–T cell synaptic interactions drive the differentiation of protective CD8+ T cells | Nature Immunology | 2013 | 144 |
| 26 | Inflammatory arthritis increases mouse osteoclast precursors with myeloid suppressor function | Journal of Clinical Investigation | 2012 | 138 |
| 27 | Assessment of a Deep Learning Model Based on Electronic Health Record Data to Forecast Clinical Outcomes in Patients With Rheumatoid Arthritis | JAMA Network Open | 2019 | 135 |
| 28 | Bisphosphonate Therapy Improves the Outcome of Conventional Periodontal Treatment: Results of a 12-Month, Randomized, Placebo-Controlled Study | Journal of Periodontology | 2005 | 132 |
| 29 | Measuring Hospital Quality Using Pediatric Readmission and Revisit Rates | Pediatrics | 2013 | 121 |
| 30 | Daily treatment with parathyroid hormone is associated with an increase in vertebral cross-sectional area in postmenopausal women with glucocorticoid-induced osteoporosis | Osteoporosis International | 2003 | 111 |
| 31 | Progression of radiographic hip osteoarthritis over eight years in a community sample of elderly white women | Arthritis and Rheumatism | 2004 | 110 |
| 32 | Sport practice and osteoarthritis of the limbs | Osteoarthritis and Cartilage | 1997 | 102 |
| 33 | Patient preferences and satisfaction in the treatment of rheumatoid arthritis with biologic therapy | Patient Preference and Adherence | 2009 | 96 |
| 34 | Changes in Serum Receptor Activator of Nuclear Factor-κB Ligand, Osteoprotegerin, and Interleukin-6 Levels in Patients with Glucocorticoid-Induced Osteoporosis Treated with Human Parathyroid Hormone (1–34) | Journal of Clinical Endocrinology and Metabolism | 2004 | 86 |
| 35 | Measurement properties of the ASAS Health Index: results of a global study in patients with axial and peripheral spondyloarthritis | Annals of the Rheumatic Diseases | 2018 | 85 |
| 36 | The COVID-19 Global Rheumatology Alliance: collecting data in a pandemic | Nature Reviews Rheumatology | 2020 | 85 |
| 37 | An Update on Glucocorticoid-Induced Osteoporosis | Rheumatic Disease Clinics of North America | 2001 | 82 |
| 38 | CD45-Csk Phosphatase-Kinase Titration Uncouples Basal and Inducible T Cell Receptor Signaling during Thymic Development | Immunity | 2010 | 78 |
| 39 | The IRF5–TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share | Human Molecular Genetics | 2015 | 74 |
| 40 | Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis | Nature Communications | 2016 | 73 |
| 41 | Outcomes in Systemic Sclerosis–Related Lung Disease After Lung Transplantation | Transplantation | 2013 | 72 |
| 42 | Particular HLA-DRB1 shared epitope genotypes are strongly associated with rheumatoid vasculitis | Arthritis and Rheumatism | 2004 | 71 |
| 43 | A role for muscarinic receptors in neutrophil extracellular trap formation and levamisole-induced autoimmunity | JCI Insight | 2017 | 69 |
| 44 | Baseline use of hydroxychloroquine in systemic lupus erythematosus does not preclude SARS-CoV-2 infection and severe COVID-19 | Annals of the Rheumatic Diseases | 2020 | 67 |
| 45 | Neurologic Manifestations of Primary Sjögren Syndrome | Rheumatic Disease Clinics of North America | 2017 | 65 |
| 46 | Fatigue in Rheumatoid Arthritis | Current Rheumatology Reports | 2017 | 64 |
| 47 | B Cell–Intrinsic TLR7 Signaling Is Required for Optimal B Cell Responses during Chronic Viral Infection | Journal of Immunology | 2013 | 63 |
| 48 | Cutting Edge: An In Vivo Reporter Reveals Active B Cell Receptor Signaling in the Germinal Center | Journal of Immunology | 2015 | 63 |
| 49 | NF-κB/MAPK activation underlies ACVR1-mediated inflammation in human heterotopic ossification | JCI Insight | 2018 | 63 |
| 50 | IgM and IgD B cell receptors differentially respond to endogenous antigens and control B cell fate | ELife | 2018 | 62 |
