| Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease | Alzheimer's and Dementia | 2011 | 4.2K |
| A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera | Nature | 2005 | 2.8K |
| Coming of age: ten years of next-generation sequencing technologies | Nature Reviews Genetics | 2016 | 2.2K |
| Biological basis of the behavior of sick animals | Neuroscience and Biobehavioral Reviews | 1988 | 1.6K |
| De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling | Nature | 2004 | 1.5K |
| Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America | Clinical Infectious Diseases | 2016 | 1.4K |
| Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils | Nature | 1998 | 1.3K |
| Structure, variation, and assembly of the root-associated microbiomes of rice | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 1.2K |
| A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis | American Journal of Human Genetics | 2004 | 1.2K |
| Characterization of polyploid wheat genomic diversity using a high-density 90,000 single nucleotide polymorphism array | Plant Biotechnology Journal | 2014 | 1.1K |
| Galectins as modulators of tumour progression | Nature Reviews Cancer | 2005 | 1.1K |
| Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor | Nature | 2013 | 1.1K |
| Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort study | Lancet, The | 2009 | 1.1K |
| The global burden of mental disorders: an update from the WHO World Mental Health (WMH) surveys | Epidemiologia E Psichiatria Sociale | 2009 | 1K |
| Translational control in mammalian cells | Annual Review of Biochemistry | 1991 | 999 |
| The global distribution of the arbovirus vectors Aedes aegypti and Ae. albopictus | ELife | 2015 | 995 |
| Present and future arboviral threats | Antiviral Research | 2010 | 927 |
| Ingested plastic transfers hazardous chemicals to fish and induces hepatic stress | Scientific Reports | 2013 | 924 |
| Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing | Nature Genetics | 2019 | 917 |
| Obstructive sleep apnea-hypopnea and incident stroke: the sleep heart health study | American Journal of Respiratory and Critical Care Medicine | 2010 | 877 |
| Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture | Nature Genetics | 2012 | 866 |
| Reduced Paneth cell alpha-defensins in ileal Crohn's disease | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 847 |
| Gut inflammation provides a respiratory electron acceptor for Salmonella | Nature | 2010 | 830 |
| Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product | Nature | 1987 | 822 |
| Policy: Classify plastic waste as hazardous | Nature | 2013 | 814 |
