| Suicide and suicidal behavior | Epidemiologic Reviews | 2008 | 1.5K |
| Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 681 |
| Detection and characterization of placental microRNAs in maternal plasma | Clinical Chemistry | 2008 | 679 |
| Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus | Nature Genetics | 2008 | 598 |
| Large artery intracranial occlusive disease: a large worldwide burden but a relatively neglected frontier | Stroke | 2008 | 451 |
| Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: implications for Th17-mediated inflammation in auto-immunity | Clinical Immunology | 2008 | 409 |
| MicroRNA-223 is commonly repressed in hepatocellular carcinoma and potentiates expression of Stathmin1 | Gastroenterology | 2008 | 372 |
| Microfluidics digital PCR reveals a higher than expected fraction of fetal DNA in maternal plasma | Clinical Chemistry | 2008 | 346 |
| Traditional Chinese medicine | Lancet, The | 2008 | 310 |
| Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians | Diabetes | 2008 | 291 |
| Hepatocellular carcinoma: current management and recent advances | Hepatobiliary and Pancreatic Diseases International | 2008 | 282 |
| Noninvasive prenatal diagnosis of monogenic diseases by digital size selection and relative mutation dosage on DNA in maternal plasma | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 266 |
| Ocular adnexal lymphoma associated with IgG4+ chronic sclerosing dacryoadenitis: a previously undescribed complication of IgG4-related sclerosing disease | American Journal of Surgical Pathology | 2008 | 239 |
| OCT2 polymorphisms and in-vivo renal functional consequence: studies with metformin and cimetidine | Pharmacogenetics and Genomics | 2008 | 216 |
| OLGA staging for gastritis: a tutorial | Digestive and Liver Disease | 2008 | 200 |
| Cardiovascular risk profile of patients with psoriatic arthritis compared to controls--the role of inflammation | Rheumatology | 2008 | 193 |
| Immunomodulatory and anti-SARS activities of Houttuynia cordata | Journal of Ethnopharmacology | 2008 | 189 |
| Public-health risks of melamine in milk products | Lancet, The | 2008 | 177 |
| Development of a quality assessment tool for systematic reviews of observational studies (QATSO) of HIV prevalence in men having sex with men and associated risk behaviours | Emerging Themes in Epidemiology | 2008 | 175 |
| WNT5A exhibits tumor-suppressive activity through antagonizing the Wnt/beta-catenin signaling, and is frequently methylated in colorectal cancer | Clinical Cancer Research | 2008 | 166 |
| Erectile dysfunction predicts coronary heart disease in type 2 diabetes | Journal of the American College of Cardiology | 2008 | 158 |
| Risk vs benefit of anti-thrombotic therapy in ischaemic stroke patients with cerebral microbleeds | Journal of Neurology | 2008 | 152 |
| Synthesis and anti-cancer activity of benzothiazole containing phthalimide on human carcinoma cell lines | Bioorganic and Medicinal Chemistry | 2008 | 150 |
| Endotoxemia is related to systemic inflammation and atherosclerosis in peritoneal dialysis patients | Clinical Journal of the American Society of Nephrology: CJASN | 2008 | 148 |
| The Hong Kong diastolic heart failure study: a randomised controlled trial of diuretics, irbesartan and ramipril on quality of life, exercise capacity, left ventricular global and regional function in heart failure with a normal ejection fraction | Heart | 2008 | 139 |
