| # | Title | Journal | Year | Citations |
|---|
| 1 | Hereditary Early-Onset Parkinson's Disease Caused by Mutations in PINK1 | Science | 2004 | 3,060 |
| 2 | Mesenchymal Stem Cells: Revisiting History, Concepts, and Assays | Cell Stem Cell | 2008 | 1,392 |
| 3 | Isolation and Expansion of Adult Cardiac Stem Cells From Human and Murine Heart | Circulation Research | 2004 | 1,374 |
| 4 | Induction of Lymphocyte Apoptosis by Tumor Cell Secretion of FasL-bearing Microvesicles | Journal of Experimental Medicine | 2002 | 660 |
| 5 | Phenotypic Effects of Biglycan Deficiency Are Linked to Collagen Fibril Abnormalities, Are Synergized by Decorin Deficiency, and Mimic Ehlers-Danlos-Like Changes in Bone and Other Connective Tissues | Journal of Bone and Mineral Research | 2002 | 392 |
| 6 | Adiponectin expression in human epicardial adipose tissue in vivo is lower in patients with coronary artery disease | Cytokine | 2005 | 358 |
| 7 | Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice | EMBO Journal | 2000 | 316 |
| 8 | Oral probiotic administration induces interleukin-10 production and prevents spontaneous autoimmune diabetes in the non-obese diabetic mouse | Diabetologia | 2005 | 309 |
| 9 | The conditional inactivation of the β-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility | Journal of Cell Biology | 2003 | 297 |
| 10 | Thyroxine in Goiter,Helicobacter pyloriInfection, and Chronic Gastritis | New England Journal of Medicine | 2006 | 284 |
| 11 | Emilin1 Links TGF-β Maturation to Blood Pressure Homeostasis | Cell | 2006 | 274 |
| 12 | Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination | Nature Cell Biology | 2006 | 259 |
| 13 | Alpha-SMA expression in hepatic stellate cells and quantitative analysis of hepatic fibrosis in cirrhosis and in recurrent chronic hepatitis after liver transplantation | Digestive and Liver Disease | 2005 | 245 |
| 14 | Cross-Talk between Activated Human NK Cells and CD4+ T Cells via OX40-OX40 Ligand Interactions | Journal of Immunology | 2004 | 238 |
| 15 | Mesoangioblasts — vascular progenitors for extravascular mesodermal tissues | Current Opinion in Genetics and Development | 2003 | 234 |
| 16 | Loss of MMP-2 disrupts skeletal and craniofacial development and results in decreased bone mineralization, joint erosion and defects in osteoblast and osteoclast growth | Human Molecular Genetics | 2007 | 202 |
| 17 | TrkA alternative splicing | Cancer Cell | 2004 | 194 |
| 18 | Combined expression of pTα and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 184 |
| 19 | The Schneiderian Membrane Contains Osteoprogenitor Cells: In Vivo and In Vitro Study | Calcified Tissue International | 2009 | 183 |
| 20 | HOXB7 Constitutively Activates Basic Fibroblast Growth Factor in Melanomas | Molecular and Cellular Biology | 1996 | 182 |
| 21 | RENKCTD11 is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 173 |
| 22 | Human MRE11 is inactivated in mismatch repair‐deficient cancers | EMBO Reports | 2002 | 169 |
| 23 | Human immunodeficiency virus 1 Nef protein downmodulates the ligands of the activating receptor NKG2D and inhibits natural killer cell-mediated cytotoxicity | Journal of General Virology | 2007 | 161 |
| 24 | Short-Term Treatment With Atorvastatin Reduces Platelet CD40 Ligand and Thrombin Generation in Hypercholesterolemic Patients | Circulation | 2005 | 159 |
| 25 | Comorbidity, Hospitalization, and Mortality in COPD: Results from a Longitudinal Study | Lung | 2010 | 145 |
| 26 | Postnatal Skeletal Stem Cells | Methods in Enzymology | 2006 | 142 |
| 27 | Control of target cell survival in thyroid autoimmunity by T helper cytokines via regulation of apoptotic proteins | Nature Immunology | 2000 | 139 |
| 28 | Type 5 phosphodiesterase expression in the human vagina | Urology | 2002 | 136 |
| 29 | Patterns of genomic instability in gastric cancer: clinical implications and perspectives | Annals of Oncology | 2006 | 133 |
| 30 | Evaluation of apoptosis and the glucocorticoid receptor in the cartilage growth plate and metaphyseal bone cells of rats after high-dose treatment with corticosterone | Bone | 2000 | 132 |
| 31 | Inhibition of platelet aggregation by aspirin progressively decreases in long-term treated patients | Journal of the American College of Cardiology | 2004 | 130 |
| 32 | Notch3 and pre-TCR interaction unveils distinct NF-κB pathways in T-cell development and leukemia | EMBO Journal | 2006 | 130 |
| 33 | Poly(ADP-ribose) polymerase (PARP) inhibition or PARP-1 gene deletion reduces angiogenesis | European Journal of Cancer | 2007 | 128 |
| 34 | Assignment of a locus for autosomal dominant idiopathic scoliosis (IS) to human chromosome 17p11 | Human Genetics | 2002 | 125 |
| 35 | Involvement of hTERT in apoptosis induced by interference with Bcl-2 expression and function | Cell Death and Differentiation | 2005 | 124 |
| 36 | Age-Dependent Demise of GNAS-Mutated Skeletal Stem Cells and “Normalization” of Fibrous Dysplasia of Bone | Journal of Bone and Mineral Research | 2008 | 119 |
| 37 | Tartrate-resistant acid phosphate activity as osteoclastic marker: Sensitivity of cytochemical assessment and serum assay in comparison with standardized osteoclast histomorphometry | Osteoporosis International | 1997 | 117 |
| 38 | Regulation of Intracellular pH Mediates Bax Activation in HeLa Cells Treated with Staurosporine or Tumor Necrosis Factor-α | Journal of Biological Chemistry | 2002 | 115 |
| 39 | Native group-III metabotropic glutamate receptors are coupled to the mitogen-activated protein kinase/phosphatidylinositol-3-kinase pathways | Journal of Neurochemistry | 2002 | 115 |
| 40 | The BCL2A1 gene as a pre–T cell receptor–induced regulator of thymocyte survival | Journal of Experimental Medicine | 2005 | 109 |
| 41 | p38 MAPK activation controls the TLR3-mediated up-regulation of cytotoxicity and cytokine production in human NK cells | Blood | 2004 | 108 |
| 42 | Dilated intercellular spaces and acid reflux at the distal and proximal oesophagus in patients with non‐erosive gastro‐oesophageal reflux disease | Alimentary Pharmacology and Therapeutics | 2007 | 107 |
| 43 | Transforming growth factor-β1 enhances the invasiveness of human MDA-MB-231 breast cancer cells by up-regulating urokinase activity | International Journal of Cancer | 1998 | 106 |
| 44 | Lipid microdomains contribute to apoptosis-associated modifications of mitochondria in T cells | Cell Death and Differentiation | 2005 | 106 |
| 45 | The innate osteogenic potential of the maxillary sinus (Schneiderian) membrane: an ectopic tissue transplant model simulating sinus lifting | International Journal of Oral and Maxillofacial Surgery | 2010 | 105 |
| 46 | Fibrous Dysplasia as a Stem Cell Disease | Journal of Bone and Mineral Research | 2006 | 103 |
| 47 | Preconditioning effects of levosimendan in coronary artery bypass grafting—a pilot study | British Journal of Anaesthesia | 2006 | 103 |
| 48 | Renal Osteodystrophy in Predialysis and Hemodialysis Patients: Comparison of Histologic Patterns and Diagnostic Predictivity of Intact PTH | Nephron | 2002 | 101 |
| 49 | Mutations of an intronic repeat induce impaired MRE11 expression in primary human cancer with microsatellite instability | Oncogene | 2004 | 101 |
| 50 | Portal vein thrombosis in liver cirrhosis | Internal and Emergency Medicine | 2008 | 101 |
