| # | Title | Journal | Year | Citations |
|---|
| 1 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 4 | Multiple common variants for celiac disease influencing immune gene expression | Nature Genetics | 2010 | 871 |
| 5 | Consensus guidelines for the detection of immunogenic cell death | OncoImmunology | 2014 | 686 |
| 6 | Dysregulated Epstein-Barr virus infection in the multiple sclerosis brain | Journal of Experimental Medicine | 2007 | 630 |
| 7 | Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors | Nature Medicine | 2015 | 540 |
| 8 | Erectile dysfunction | Nature Reviews Disease Primers | 2016 | 475 |
| 9 | HLA-DPB1 glutamate 69: a genetic marker of beryllium disease | Science | 1993 | 451 |
| 10 | Albumin-bound formulation of paclitaxel (Abraxane® ABI-007) in the treatment of breast cancer | International Journal of Nanomedicine | 2009 | 450 |
| 11 | Prevalence and Clinical Significance of Left Atrial Remodeling in Competitive Athletes | Journal of the American College of Cardiology | 2005 | 411 |
| 12 | Complications of Cushing's syndrome: state of the art | Lancet Diabetes and Endocrinology,the | 2016 | 371 |
| 13 | Circadian regulation of glucose, lipid, and energy metabolism in humans | Metabolism: Clinical and Experimental | 2018 | 345 |
| 14 | Microsatellite instability as a marker of prognosis and response to therapy: A meta-analysis of colorectal cancer survival data | European Journal of Cancer | 2010 | 328 |
| 15 | Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death | Frontiers in Immunology | 2015 | 317 |
| 16 | CAR-T cells: the long and winding road to solid tumors | Cell Death and Disease | 2018 | 312 |
| 17 | Meta-Analysis of Genome-Wide Association Studies in Celiac Disease and Rheumatoid Arthritis Identifies Fourteen Non-HLA Shared Loci | PLoS Genetics | 2011 | 307 |
| 18 | NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration | Nature Cell Biology | 2011 | 306 |
| 19 | Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells | EMBO Journal | 2008 | 303 |
| 20 | Histone deacetylase and Cullin3–RENKCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation | Nature Cell Biology | 2010 | 292 |
| 21 | Low testosterone levels predict clinical adverse outcomes in SARS‐CoV‐2 pneumonia patients | Andrology | 2021 | 283 |
| 22 | MicroRNA profiling in human medulloblastoma | International Journal of Cancer | 2009 | 278 |
| 23 | Decreased C-Src Expression Enhances Osteoblast Differentiation and Bone Formation | Journal of Cell Biology | 2000 | 275 |
| 24 | The Urokinase Plasminogen Activator System: A Target for Anti-Cancer Therapy | Current Cancer Drug Targets | 2009 | 265 |
| 25 | Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells | Blood | 2009 | 263 |
| 26 | Cardiovascular risk associated with testosterone-boosting medications: a systematic review and meta-analysis | Expert Opinion on Drug Safety | 2014 | 260 |
| 27 | Psychological Aspects and Eating Habits during COVID-19 Home Confinement: Results of EHLC-COVID-19 Italian Online Survey | Nutrients | 2020 | 258 |
| 28 | Antigen-activated human T lymphocytes express cell-surface NKG2D ligands via an ATM/ATR-dependent mechanism and become susceptible to autologous NK- cell lysis | Blood | 2007 | 257 |
| 29 | Male Oxidative Stress Infertility (MOSI): Proposed Terminology and Clinical Practice Guidelines for Management of Idiopathic Male Infertility | World Journal of Men?s Health | 2019 | 256 |
| 30 | The Interplay of Reactive Oxygen Species, Hypoxia, Inflammation, and Sirtuins in Cancer Initiation and Progression | Oxidative Medicine and Cellular Longevity | 2016 | 245 |
| 31 | Androgenetic alopecia: a review | Endocrine | 2017 | 242 |
| 32 | The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy | Cell Death and Differentiation | 2010 | 233 |
| 33 | TDP-43 and FUS RNA-binding Proteins Bind Distinct Sets of Cytoplasmic Messenger RNAs and Differently Regulate Their Post-transcriptional Fate in Motoneuron-like Cells | Journal of Biological Chemistry | 2012 | 233 |
| 34 | Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately controlled with metformin (TOSCA.IT): a randomised, multicentre trial | Lancet Diabetes and Endocrinology,the | 2017 | 231 |
| 35 | Endogenous Cardiac Stem Cells | Progress in Cardiovascular Diseases | 2007 | 229 |
| 36 | Covid‐19 and diabetes mellitus: unveiling the interaction of two pandemics | Diabetes/Metabolism Research and Reviews | 2020 | 228 |
| 37 | Glucocorticoid receptor-mediated suppression of the interleukin 2 gene expression through impairment of the cooperativity between nuclear factor of activated T cells and AP-1 enhancer elements. | Journal of Experimental Medicine | 1992 | 226 |
| 38 | Recruitment of circulating NK cells through decidual tissues: a possible mechanism controlling NK cell accumulation in the uterus during early pregnancy | Blood | 2008 | 222 |
| 39 | Cytoreductive surgery (peritonectomy procedures) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) in the treatment of diffuse peritoneal carcinomatosis from ovarian cancer | Cancer | 2008 | 216 |
| 40 | Endocrine Disrupting Chemicals: Effects on Endocrine Glands | Frontiers in Endocrinology | 2019 | 212 |
| 41 | Prevalence, characteristics and severity of non-alcoholic fatty liver disease in patients with chronic plaque psoriasis | Journal of Hepatology | 2009 | 209 |
| 42 | Hedgehog controls neural stem cells through p53-independent regulation of Nanog | EMBO Journal | 2010 | 208 |
| 43 | Effects of Five-Year Treatment with Testosterone Undecanoate on Metabolic and Hormonal Parameters in Ageing Men with Metabolic Syndrome | International Journal of Endocrinology | 2014 | 208 |
| 44 | Study of SARS-CoV-2 in semen and urine samples of a volunteer with positive naso-pharyngeal swab | Journal of Endocrinological Investigation | 2020 | 207 |
| 45 | Central obesity, smoking habit, and hypertension are associated with lower antibody titres in response to COVID‐19 mRNA vaccine | Diabetes/Metabolism Research and Reviews | 2022 | 203 |
| 46 | Sperm recovery and ICSI outcomes in Klinefelter syndrome: a systematic review and meta-analysis | Human Reproduction Update | 2017 | 200 |
| 47 | Testosterone Supplementation and Sexual Function: A Meta-Analysis Study | Journal of Sexual Medicine | 2014 | 195 |
| 48 | The multiple functions of Numb | Experimental Cell Research | 2010 | 189 |
| 49 | Adult-onset autoimmune diabetes: current knowledge and implications for management | Nature Reviews Endocrinology | 2017 | 187 |
| 50 | Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 180 |
