| # | Title | Journal | Year | Citations |
|---|
| 1 | The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data | Brain Imaging and Behavior | 2014 | 696 |
| 2 | Myasthenia Gravis | New England Journal of Medicine | 2016 | 644 |
| 3 | Identification of common variants associated with human hippocampal and intracranial volumes | Nature Genetics | 2012 | 594 |
| 4 | EFNS guidelines on the diagnosis and management of European Lyme neuroborreliosis | European Journal of Neurology | 2010 | 585 |
| 5 | Genome-wide association studies establish that human intelligence is highly heritable and polygenic | Molecular Psychiatry | 2011 | 571 |
| 6 | Subcortical brain volume differences in participants with attention deficit hyperactivity disorder in children and adults: a cross-sectional mega-analysis | Lancet Psychiatry,the | 2017 | 565 |
| 7 | Are 90% of deaths from cancer caused by metastases? | Cancer Medicine | 2019 | 536 |
| 8 | Myasthenia gravis | Nature Reviews Disease Primers | 2019 | 421 |
| 9 | Permanent Neonatal Diabetes due to Mutations in KCNJ11 Encoding Kir6.2 | Diabetes | 2004 | 350 |
| 10 | The impact of frailty on ICU and 30-day mortality and the level of care in very elderly patients (≥ 80 years) | Intensive Care Medicine | 2017 | 311 |
| 11 | Mutations in the CEL VNTR cause a syndrome of diabetes and pancreatic exocrine dysfunction | Nature Genetics | 2006 | 296 |
| 12 | Efficacy of faecal microbiota transplantation for patients with irritable bowel syndrome in a randomised, double-blind, placebo-controlled study | Gut | 2020 | 291 |
| 13 | Myasthenia gravis — autoantibody characteristics and their implications for therapy | Nature Reviews Neurology | 2016 | 286 |
| 14 | Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre study | Multiple Sclerosis Journal | 2015 | 249 |
| 15 | A recurrent de novo mutation in KCNC1 causes progressive myoclonus epilepsy | Nature Genetics | 2015 | 245 |
| 16 | Perforated peptic ulcer | Lancet, The | 2015 | 240 |
| 17 | ESTES guidelines: acute mesenteric ischaemia | European Journal of Trauma and Emergency Surgery | 2016 | 240 |
| 18 | Recommendations for initiation and cessation of enzyme replacement therapy in patients with Fabry disease: the European Fabry Working Group consensus document | Orphanet Journal of Rare Diseases | 2015 | 239 |
| 19 | Disease‐modifying treatments for multiple sclerosis – a review of approved medications | European Journal of Neurology | 2016 | 238 |
| 20 | Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway–dependent and PI3K pathway–independent mechanisms | Nature Medicine | 2011 | 231 |
| 21 | The contribution of frailty, cognition, activity of daily life and comorbidities on outcome in acutely admitted patients over 80 years in European ICUs: the VIP2 study | Intensive Care Medicine | 2020 | 230 |
| 22 | Daily Duration of Vitamin D Synthesis in Human Skin with Relation to Latitude, Total Ozone, Altitude, Ground Cover, Aerosols and Cloud Thickness | Photochemistry and Photobiology | 2005 | 229 |
| 23 | Fetal cardiac output, distribution to the placenta and impact of placental compromise | Ultrasound in Obstetrics and Gynecology | 2006 | 222 |
| 24 | Identification of six new susceptibility loci for invasive epithelial ovarian cancer | Nature Genetics | 2015 | 221 |
| 25 | Middle cerebral artery blood flow velocities and pulsatility index and the cerebroplacental pulsatility ratio: longitudinal reference ranges and terms for serial measurements | Ultrasound in Obstetrics and Gynecology | 2007 | 220 |
| 26 | Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma | Nature Genetics | 2015 | 218 |
| 27 | Continuing Stability of Center Differences in Pediatric Diabetes Care: Do Advances in Diabetes Treatment Improve Outcome? | Diabetes Care | 2007 | 194 |
| 28 | Long-term quality of life in patients with vestibular schwannoma: an international multicenter cross-sectional study comparing microsurgery, stereotactic radiosurgery, observation, and nontumor controls | Journal of Neurosurgery | 2015 | 192 |
| 29 | EANO guideline on the diagnosis and treatment of vestibular schwannoma | Neuro-Oncology | 2020 | 190 |
| 30 | Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX , SOX4 , and IRX3 | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 189 |
| 31 | Discriminating Variable Test and Selectivity Ratio Plot: Quantitative Tools for Interpretation and Variable (Biomarker) Selection in Complex Spectral or Chromatographic Profiles | Analytical Chemistry | 2009 | 188 |
| 32 | Transanal total mesorectal excision for rectal cancer has been suspended in Norway | British Journal of Surgery | 2019 | 188 |
| 33 | Toward a Consensus on Centralization in Surgery | Annals of Surgery | 2018 | 187 |
| 34 | Periprosthetic Femoral Fracture within Two Years After Total Hip Replacement | Journal of Bone and Joint Surgery - Series A | 2014 | 185 |
| 35 | Mutations in the Insulin Gene Can Cause MODY and Autoantibody-Negative Type 1 Diabetes | Diabetes | 2008 | 184 |
| 36 | The status of intensive care medicine research and a future agenda for very old patients in the ICU | Intensive Care Medicine | 2017 | 182 |
| 37 | Survival and cause of death in multiple sclerosis: a 60-year longitudinal population study | Journal of Neurology, Neurosurgery and Psychiatry | 2017 | 180 |
| 38 | Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT) | Molecular Psychiatry | 2014 | 178 |
| 39 | The genomic landscape and evolution of endometrial carcinoma progression and abdominopelvic metastasis | Nature Genetics | 2016 | 174 |
| 40 | Acute bacterial conjunctivitis | Acta Ophthalmologica | 2008 | 168 |
| 41 | Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation | Nature Medicine | 2013 | 156 |
| 42 | Brain atrophy and disability progression in multiple sclerosis patients: a 10-year follow-up study | Journal of Neurology, Neurosurgery and Psychiatry | 2014 | 155 |
| 43 | Fetal growth restriction and birth defects with newer and older antiepileptic drugs during pregnancy | Journal of Neurology | 2014 | 152 |
| 44 | Profiles of Genomic Instability in High-Grade Serous Ovarian Cancer Predict Treatment Outcome | Clinical Cancer Research | 2012 | 150 |
| 45 | The Complement Control-Related Genes CSMD1 and CSMD2 Associate to Schizophrenia | Biological Psychiatry | 2011 | 149 |
| 46 | A maternal hypomethylation syndrome presenting as transient neonatal diabetes mellitus | Human Genetics | 2006 | 147 |
| 47 | Exome sequencing reveals FAM20c mutations associated with fibroblast growth factor 23–related hypophosphatemia, dental anomalies, and ectopic calcification | Journal of Bone and Mineral Research | 2013 | 144 |
| 48 | Effects of varying dietary content of fermentable short‐chain carbohydrates on symptoms, fecal microenvironment, and cytokine profiles in patients with irritable bowel syndrome | Neurogastroenterology and Motility | 2017 | 144 |
| 49 | Point of Care Ultrasound: A WFUMB Position Paper | Ultrasound in Medicine and Biology | 2017 | 143 |
| 50 | Congenital Stromal Dystrophy of the Cornea Caused by a Mutation in the Decorin Gene | | 2005 | 140 |
