| Gastric cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up | Annals of Oncology | 2016 | 796 |
| Metastatic non-small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up | Annals of Oncology | 2016 | 590 |
| Cholesterol Lowering in Intermediate-Risk Persons without Cardiovascular Disease | New England Journal of Medicine | 2016 | 440 |
| Blood-Pressure Lowering in Intermediate-Risk Persons without Cardiovascular Disease | New England Journal of Medicine | 2016 | 382 |
| Extended-Release Naltrexone to Prevent Opioid Relapse in Criminal Justice Offenders | New England Journal of Medicine | 2016 | 207 |
| Acute Impact of Tobacco vs Electronic Cigarette Smoking on Oxidative Stress and Vascular Function | Chest | 2016 | 201 |
| Blood-Pressure and Cholesterol Lowering in Persons without Cardiovascular Disease | New England Journal of Medicine | 2016 | 199 |
| Out of southern East Asia: the natural history of domestic dogs across the world | Cell Research | 2016 | 177 |
| Effect of Pathologic Tumor Response and Nodal Status on Survival in the Medical Research Council Adjuvant Gastric Infusional Chemotherapy Trial | Journal of Clinical Oncology | 2016 | 144 |
| Smooth Muscle Enriched Long Noncoding RNA (SMILR) Regulates Cell Proliferation | Circulation | 2016 | 142 |
| The IGNITE network: a model for genomic medicine implementation and research | BMC Medical Genomics | 2016 | 139 |
| Comparison of EndoPredict and EPclin With Oncotype DX Recurrence Score for Prediction of Risk of Distant Recurrence After Endocrine Therapy | Journal of the National Cancer Institute | 2016 | 131 |
| Challenges in molecular testing in non-small-cell lung cancer patients with advanced disease | Lancet, The | 2016 | 113 |
| Vancouver Transcatheter Aortic Valve Replacement Clinical Pathway: Minimalist Approach, Standardized Care, and Discharge Criteria to Reduce Length of Stay | Circulation: Cardiovascular Quality and Outcomes | 2016 | 93 |
| High-dose chemotherapy with autologous haemopoietic stem cell transplantation for newly diagnosed primary CNS lymphoma: a prospective, single-arm, phase 2 trial | Lancet Haematology,the | 2016 | 93 |
| Prognostic factors influencing the outcome of rotator cuff repair: a systematic review | Knee Surgery, Sports Traumatology, Arthroscopy | 2016 | 90 |
| Ga-DOTATATE for Tumor Localization in Tumor-Induced Osteomalacia | Journal of Clinical Endocrinology and Metabolism | 2016 | 84 |
| Gait Speed Predicts 30-Day Mortality After Transcatheter Aortic Valve Replacement: Results From the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry | Circulation | 2016 | 83 |
| Management of Recurrent Retroperitoneal Sarcoma (RPS) in the Adult: A Consensus Approach from the Trans-Atlantic RPS Working Group | Annals of Surgical Oncology | 2016 | 82 |
| Synchronous Endometrial and Ovarian Carcinomas: Evidence of Clonality | Journal of the National Cancer Institute | 2016 | 81 |
| p53 as guardian of the mitochondrial genome | FEBS Letters | 2016 | 76 |
| Inhibition of Galectin-3 Pathway Prevents Isoproterenol-Induced Left Ventricular Dysfunction and Fibrosis in Mice | Hypertension | 2016 | 73 |
| TWIST1 Integrates Endothelial Responses to Flow in Vascular Dysfunction and Atherosclerosis | Circulation Research | 2016 | 71 |
| Frequency and Severity of Pulmonary Hemorrhage in Patients Undergoing Percutaneous CT-guided Transthoracic Lung Biopsy: Single-Institution Experience of 1175 Cases | Radiology | 2016 | 70 |
| Prognostic factors for progression-free and overall survival in advanced biliary tract cancer | Annals of Oncology | 2016 | 69 |
