| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | A mutation in the tRNALeu(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies | Nature | 1990 | 1,981 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 4 | Adiponectin and AdipoR1 regulate PGC-1α and mitochondria by Ca2+ and AMPK/SIRT1 | Nature | 2010 | 859 |
| 5 | 3-Mercaptopyruvate Sulfurtransferase Produces Hydrogen Sulfide and Bound Sulfane Sulfur in the Brain | Antioxidants and Redox Signaling | 2009 | 800 |
| 6 | Cells Respond to Mechanical Stress by Rapid Disassembly of Caveolae | Cell | 2011 | 791 |
| 7 | Brain hydrogen sulfide is severely decreased in Alzheimer's disease | Biochemical and Biophysical Research Communications | 2002 | 739 |
| 8 | Development of a Highly Selective Fluorescence Probe for Hydrogen Sulfide | Journal of the American Chemical Society | 2011 | 614 |
| 9 | Fibrosis and adipogenesis originate from a common mesenchymal progenitor in skeletal muscle | Journal of Cell Science | 2011 | 517 |
| 10 | Skeletal Muscle FOXO1 (FKHR) Transgenic Mice Have Less Skeletal Muscle Mass, Down-regulated Type I (Slow Twitch/Red Muscle) Fiber Genes, and Impaired Glycemic Control | Journal of Biological Chemistry | 2004 | 488 |
| 11 | Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2012 | 479 |
| 12 | Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice | Nature Genetics | 1999 | 467 |
| 13 | BDNF function and intracellular signaling in neurons | Histology and Histopathology | 2010 | 464 |
| 14 | Stargazin modulates AMPA receptor gating and trafficking by distinct domains | Nature | 2005 | 447 |
| 15 | A Source of Hydrogen Sulfide and a Mechanism of Its Release in the Brain | Antioxidants and Redox Signaling | 2009 | 444 |
| 16 | A mutation in the ceruloplasmin gene is associated with systemic hemosiderosis in humans | Nature Genetics | 1995 | 442 |
| 17 | Chronic Stress Induces Impairment of Spatial Working Memory Because of Prefrontal Dopaminergic Dysfunction | Journal of Neuroscience | 2000 | 426 |
| 18 | Possible association of Bifidobacterium and Lactobacillus in the gut microbiota of patients with major depressive disorder | Journal of Affective Disorders | 2016 | 419 |
| 19 | Vascular Endothelium Expresses 3-Mercaptopyruvate Sulfurtransferase and Produces Hydrogen Sulfide | Journal of Biochemistry | 2009 | 410 |
| 20 | Crosstalk between Glucocorticoid Receptor and Nutritional Sensor mTOR in Skeletal Muscle | Cell Metabolism | 2011 | 410 |
| 21 | The small GTPase RalA targets filamin to induce filopodia | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 407 |
| 22 | Molecular Signature of Quiescent Satellite Cells in Adult Skeletal Muscle | Stem Cells | 2007 | 402 |
| 23 | The presence of free D-serine in rat brain | FEBS Letters | 1992 | 400 |
| 24 | Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 383 |
| 25 | Generation of mice with mitochondrial dysfunction by introducing mouse mtDNA carrying a deletion into zygotes | Nature Genetics | 2000 | 366 |
| 26 | Microglia–Müller Glia Cell Interactions Control Neurotrophic Factor Production during Light-Induced Retinal Degeneration | Journal of Neuroscience | 2002 | 362 |
| 27 | Efficacy of systemic morpholino exon‐skipping in duchenne dystrophy dogs | Annals of Neurology | 2009 | 356 |
| 28 | Mutations in the integrin α7 gene cause congenital myopathy | Nature Genetics | 1998 | 355 |
| 29 | Glutamate Transporter GLAST Is Expressed in the Radial Glia–Astrocyte Lineage of Developing Mouse Spinal Cord | Journal of Neuroscience | 1997 | 352 |
| 30 | Identification of Rap1 as a Target for the Crk SH3 Domain-Binding Guanine Nucleotide-Releasing Factor C3G | Molecular and Cellular Biology | 1995 | 350 |
| 31 | Human PTRF mutations cause secondary deficiency of caveolins resulting in muscular dystrophy with generalized lipodystrophy | Journal of Clinical Investigation | 2009 | 350 |
| 32 | Nonsense-mediated mRNA decay modulates clinical outcome of genetic disease | European Journal of Human Genetics | 2006 | 348 |
| 33 | Three-dimensional reconstruction of the membrane skeleton at the plasma membrane interface by electron tomography | Journal of Cell Biology | 2006 | 343 |
| 34 | Consensus Paper: Cerebellar Development | Cerebellum | 2016 | 337 |
| 35 | Endogenous d-Serine in Rat Brain: N-Methyl-d-Aspartate Receptor-Related Distribution and Aging | Journal of Neurochemistry | 1993 | 335 |
| 36 | Evidence of novel neuronal functions of dysbindin, a susceptibility gene for schizophrenia | Human Molecular Genetics | 2004 | 334 |
| 37 | Ubiquitin carboxy-terminal hydrolase L1 binds to and stabilizes monoubiquitin in neuron | Human Molecular Genetics | 2003 | 328 |
| 38 | Mitochondrial neurogastrointestinal encephalomyopathy: An autosomal recessive disorder due to thymidine phosphorylase mutations | Annals of Neurology | 2000 | 324 |
| 39 | Cardiac side population cells have a potential to migrate and differentiate into cardiomyocytes in vitro and in vivo | Journal of Cell Biology | 2007 | 308 |
| 40 | Mice lacking bombesin receptor subtype-3 develop metabolic defects and obesity | Nature | 1997 | 295 |
| 41 | Functional Comparison of d‐Serine and Glycine in Rodents: The Effect on Cloned NMDA Receptors and the Extracellular Concentration | Journal of Neurochemistry | 1995 | 295 |
| 42 | Mutations ofARX are associated with striking pleiotropy and consistent genotype-phenotype correlation | Human Mutation | 2004 | 293 |
| 43 | Hydrogen sulfide induces calcium waves in astrocytes | FASEB Journal | 2004 | 292 |
| 44 | Hydrogen Sulfide: From Brain to Gut | Antioxidants and Redox Signaling | 2010 | 287 |
| 45 | A new mtDNA mutation associated with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) | Biochimica Et Biophysica Acta - Molecular Basis of Disease | 1991 | 280 |
| 46 | Safety and efficacy of satralizumab monotherapy in neuromyelitis optica spectrum disorder: a randomised, double-blind, multicentre, placebo-controlled phase 3 trial | Lancet Neurology, The | 2020 | 278 |
| 47 | Signaling Molecules: Hydrogen Sulfide and Polysulfide | Antioxidants and Redox Signaling | 2015 | 272 |
| 48 | Noncoding CGG repeat expansions in neuronal intranuclear inclusion disease, oculopharyngodistal myopathy and an overlapping disease | Nature Genetics | 2019 | 265 |
| 49 | Alpha-CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders | Molecular Brain | 2008 | 261 |
| 50 | Murine cystathionine γ-lyase: complete cDNA and genomic sequences, promoter activity, tissue distribution and developmental expression | Biochemical Journal | 2004 | 257 |
