# | Title | Journal | Year | Citations |
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1 | A New and Improved Population-Based Canadian Reference for Birth Weight for Gestational Age | Pediatrics | 2001 | 1,296 |
2 | Promotion of Breastfeeding Intervention Trial (PROBIT) | JAMA - Journal of the American Medical Association | 2001 | 1,242 |
3 | Canadian 24-Hour Movement Guidelines for Children and Youth: An Integration of Physical Activity, Sedentary Behaviour, and Sleep | Applied Physiology, Nutrition and Metabolism | 2016 | 1,099 |
4 | Intertumoral Heterogeneity within Medulloblastoma Subgroups | Cancer Cell | 2017 | 836 |
5 | Breastfeeding and Child Cognitive Development | Archives of General Psychiatry | 2008 | 811 |
6 | The whole-genome landscape of medulloblastoma subtypes | Nature | 2017 | 787 |
7 | Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus | Nature Genetics | 1997 | 745 |
8 | Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma | Cancer Cell | 2017 | 716 |
9 | Socio-economic disparities in pregnancy outcome: why do the poor fare so poorly? | Paediatric and Perinatal Epidemiology | 2000 | 675 |
10 | The Outcome of Neutrophil Gelatinase-Associated Lipocalin-Positive Subclinical Acute Kidney Injury | Journal of the American College of Cardiology | 2011 | 597 |
11 | Phosphoinositide 3-Kinase δ Gene Mutation Predisposes to Respiratory Infection and Airway Damage | Science | 2013 | 541 |
12 | Nocturnal Pulse Oximetry as an Abbreviated Testing Modality for Pediatric Obstructive Sleep Apnea | Pediatrics | 2000 | 496 |
13 | Practice parameter for the diagnosis and management of primary immunodeficiency | Annals of Allergy, Asthma and Immunology | 2005 | 452 |
14 | Disruption of histone methylation in developing sperm impairs offspring health transgenerationally | Science | 2015 | 426 |
15 | Parental genomic imprinting of the human IGF2 gene | Nature Genetics | 1993 | 425 |
16 | Selective cytotoxicity of intracellular amyloid β peptide1–42 through p53 and Bax in cultured primary human neurons | Journal of Cell Biology | 2002 | 404 |
17 | Preeclampsia, gestational hypertension and intrauterine growth restriction, related or independent conditions? | American Journal of Obstetrics and Gynecology | 2006 | 400 |
18 | The international EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria | Allergy: European Journal of Allergy and Clinical Immunology | 2022 | 392 |
19 | Stress During Pregnancy Affects General Intellectual and Language Functioning in Human Toddlers | Pediatric Research | 2004 | 385 |
20 | The Epidemiology of Adverse Pregnancy Outcomes: An Overview | Journal of Nutrition | 2003 | 383 |
21 | Positive Screening for Autism in Ex-preterm Infants: Prevalence and Risk Factors | Pediatrics | 2008 | 356 |
22 | Effects of prolonged and exclusive breastfeeding on child height, weight, adiposity, and blood pressure at age 6.5 y: evidence from a large randomized trial | American Journal of Clinical Nutrition | 2007 | 351 |
23 | Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders | Human Molecular Genetics | 1996 | 344 |
24 | High Rate of Recurrent De Novo Mutations in Developmental and Epileptic Encephalopathies | American Journal of Human Genetics | 2017 | 337 |
25 | Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape | Science | 2016 | 327 |
26 | Stress Pathways to Spontaneous Preterm Birth: The Role of Stressors, Psychological Distress, and Stress Hormones | American Journal of Epidemiology | 2009 | 317 |
27 | A rapid procedure for extracting genomic DNA from leukocytes | Nucleic Acids Research | 1991 | 313 |
28 | Socio-economic disparities in preterm birth: causal pathways and mechanisms | Paediatric and Perinatal Epidemiology | 2001 | 308 |
29 | Type I interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cells | Nature Immunology | 2016 | 305 |
30 | THE SMALL-FOR-DATE INFANT. II. NEUROLOGICAL AND INTELLECTUAL SEQUELAE | Pediatrics | 1972 | 303 |
31 | Why are babies getting bigger? Temporal trends in fetal growth and its determinants | Journal of Pediatrics | 2002 | 298 |
32 | Diagnosis, monitoring, and treatment of primary ciliary dyskinesia: PCD foundation consensus recommendations based on state of the art review | Pediatric Pulmonology | 2016 | 297 |
33 | Myoblast transfer in duchenne muscular dystrophy | Annals of Neurology | 1993 | 291 |
34 | Haploinsufficiency of HDAC4 Causes Brachydactyly Mental Retardation Syndrome, with Brachydactyly Type E, Developmental Delays, and Behavioral Problems | American Journal of Human Genetics | 2010 | 273 |
35 | Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort | Lancet Oncology, The | 2018 | 268 |
36 | How big is too big? The perinatal consequences of fetal macrosomia | American Journal of Obstetrics and Gynecology | 2008 | 259 |
37 | Does breast feeding help protect against atopic disease? Biology, methodology, and a golden jubilee of controversy | Journal of Pediatrics | 1988 | 253 |
38 | Infant growth and health outcomes associated with 3 compared with 6 mo of exclusive breastfeeding | American Journal of Clinical Nutrition | 2003 | 253 |
39 | Caspase-6 Role in Apoptosis of Human Neurons, Amyloidogenesis, and Alzheimer's Disease | Journal of Biological Chemistry | 1999 | 250 |
40 | Effect of prolonged and exclusive breast feeding on risk of allergy and asthma: cluster randomised trial | BMJ: British Medical Journal | 2007 | 241 |
41 | Review of the Evidence on Fetal and Early Childhood Antecedents of Adult Chronic Disease | Epidemiologic Reviews | 1996 | 236 |
42 | Dramatically Different Phenotypes in Mouse Models of Human Tay-Sachs and Sandhoff Diseases | Human Molecular Genetics | 1996 | 231 |
43 | A Polymorphism Within the G6PC2 Gene Is Associated with Fasting Plasma Glucose Levels | Science | 2008 | 227 |
44 | Acquisition of theH19Methylation Imprint Occurs Differentially on the Parental Alleles during Spermatogenesis | Genomics | 1999 | 223 |
45 | Paired-Box genes are frequently expressed in cancer and often required for cancer cell survival | Oncogene | 2003 | 218 |
46 | Pediatric high-grade glioma: biologically and clinically in need of new thinking | Neuro-Oncology | 2017 | 217 |
47 | Risk Factors for and Outcomes of Acute Kidney Injury in Neonates Undergoing Complex Cardiac Surgery | Journal of Pediatrics | 2013 | 216 |
48 | Interrelationship between the Novel Peptide Ghrelin and Somatostatin/Growth Hormone-Releasing Hormone in Regulation of Pulsatile Growth Hormone Secretion | Endocrinology | 2003 | 215 |
49 | Biliary Atresia: The Canadian Experience | Journal of Pediatrics | 2007 | 215 |
50 | H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis | Nature Communications | 2019 | 215 |