| # | Title | Journal | Year | Citations |
|---|
| 1 | Altered neuregulin 1–erbB4 signaling contributes to NMDA> receptor hypofunction in schizophrenia | Nature Medicine | 2006 | 528 |
| 2 | Biology and therapeutic potential of hydrogen sulfide and hydrogen sulfide-releasing chimeras | Biochemical Pharmacology | 2013 | 270 |
| 3 | Sleep-Dependent Improvement in Visuomotor Learning: A Causal Role for Slow Waves | Sleep | 2009 | 200 |
| 4 | Local Experience-Dependent Changes in the Wake EEG after Prolonged Wakefulness | Sleep | 2013 | 178 |
| 5 | Ultra-low-dose naloxone suppresses opioid tolerance, dependence and associated changes in mu opioid receptor–G protein coupling and Gβγ signaling | Neuroscience | 2005 | 158 |
| 6 | NOSH-Aspirin: A Novel Nitric Oxide–Hydrogen Sulfide-Releasing Hybrid: A New Class of Anti-inflammatory Pharmaceuticals | ACS Medicinal Chemistry Letters | 2012 | 147 |
| 7 | Distinct changes in cortical and spinal excitability following high-frequency repetitive TMS to the human motor cortex | Experimental Brain Research | 2005 | 140 |
| 8 | Nitric-oxide-donating NSAIDs as agents for cancer prevention | Trends in Molecular Medicine | 2004 | 139 |
| 9 | SKF83959 selectively regulates phosphatidylinositol‐linked D1 dopamine receptors in rat brain | Journal of Neurochemistry | 2003 | 129 |
| 10 | Nitric oxide-donating aspirin inhibits -catenin/T cell factor (TCF) signaling in SW480 colon cancer cells by disrupting the nuclear -catenin-TCF association | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 115 |
| 11 | Hydrogen sulfide-releasing NSAIDs inhibit the growth of human cancer cells: A general property and evidence of a tissue type-independent effect | Biochemical Pharmacology | 2012 | 114 |
| 12 | Neural and Behavioral Correlates of Extended Training during Sleep Deprivation in Humans: Evidence for Local, Task-Specific Effects | Journal of Neuroscience | 2015 | 108 |
| 13 | Dissociating -Amyloid from 7 Nicotinic Acetylcholine Receptor by a Novel Therapeutic Agent, S 24795, Normalizes 7 Nicotinic Acetylcholine and NMDA Receptor Function in Alzheimer's Disease Brain | Journal of Neuroscience | 2009 | 97 |
| 14 | Non-COX-2 targets and cancer: Expanding the molecular target repertoire of chemoprevention | Biochemical Pharmacology | 2005 | 96 |
| 15 | Modulation of Gamma and Theta Spectral Amplitude and Phase Synchronization Is Associated with the Development of Visuo-Motor Learning | Journal of Neuroscience | 2011 | 90 |
| 16 | Hydrogen sulfide-releasing aspirin suppresses NF-κB signaling in estrogen receptor negative breast cancer cells in vitro and in vivo | Biochemical Pharmacology | 2012 | 83 |
| 17 | Temporal Evolution of Oscillatory Activity Predicts Performance in a Choice-Reaction Time Reaching Task | Journal of Neurophysiology | 2011 | 82 |
| 18 | Short-Term Limb Immobilization Affects Motor Performance | Journal of Motor Behavior | 2008 | 81 |
| 19 | Consistent immunohistochemical detection of intracellular β-amyloid42 in pyramidal neurons of Alzheimer's disease entorhinal cortex | Neuroscience Letters | 2002 | 80 |
| 20 | NO-donating nonsteroidal antiinflammatory drugs (NSAIDs) inhibit colon cancer cell growth more potently than traditional NSAIDs: a general pharmacological property? | Biochemical Pharmacology | 2004 | 70 |
| 21 | High-Affinity Naloxone Binding to Filamin A Prevents Mu Opioid Receptor–Gs Coupling Underlying Opioid Tolerance and Dependence | PLoS ONE | 2008 | 70 |
| 22 | Differential physiologic responses of ?7 nicotinic acetylcholine receptors to ?-amyloid1-40 and ?-amyloid1-42 | Journal of Neurobiology | 2003 | 62 |
| 23 | The mechanism of action of nitric oxide-donating aspirin | Biochemical and Biophysical Research Communications | 2007 | 62 |
| 24 | Unilateral cerebellar stroke disrupts movement preparation and motor imagery | Clinical Neurophysiology | 2006 | 61 |
| 25 | Reduced Adult Neurogenesis and Altered Emotional Behaviors in Autoimmune-Prone B-Cell Activating Factor Transgenic Mice | Biological Psychiatry | 2010 | 52 |
| 26 | S 24795 Limits β-Amyloid–α7 Nicotinic Receptor Interaction and Reduces Alzheimer's Disease-Like Pathologies | Biological Psychiatry | 2010 | 51 |
| 27 | Sleep reverts changes in human gray and white matter caused by wake-dependent training | NeuroImage | 2016 | 50 |
| 28 | Cortical and brainstem LTP-like plasticity in Huntington's disease | Brain Research Bulletin | 2008 | 49 |
| 29 | Human olfactory epithelial cells generated in vitro express diverse neuronal characteristics | Neuroscience | 2009 | 49 |
| 30 | NO-releasing NSAIDs suppress NF-κB signaling in vitro and in vivo through S-nitrosylation | Cancer Letters | 2010 | 49 |
| 31 | Gβγ that interacts with adenylyl cyclase in opioid tolerance originates from a Gs protein | Journal of Neurobiology | 2006 | 47 |
| 32 | Molecular targets of nitric-oxide-donating aspirin in cancer | Biochemical Society Transactions | 2005 | 37 |
| 33 | Inhibition of Protein Tyrosine/Mitogen-Activated Protein Kinase Phosphatase Activity Is Associated with D2 Dopamine Receptor Supersensitivity in a Rat Model of Parkinson's Disease | Molecular Pharmacology | 2002 | 35 |
| 34 | JS-K; a nitric oxide-releasing prodrug, modulates β-catenin/TCF signaling in leukemic Jurkat cells: Evidence of an S-nitrosylated mechanism | Biochemical Pharmacology | 2010 | 35 |
| 35 | Nitro-aspirin inhibits MCF-7 breast cancer cell growth: Effects on COX-2 expression and Wnt/β-catenin/TCF-4 signaling | Biochemical Pharmacology | 2009 | 34 |
| 36 | Is COX-2 a ‘collateral’ target in cancer prevention? | Biochemical Society Transactions | 2005 | 32 |
| 37 | Sleep Consolidates Motor Learning of Complex Movement Sequences in Mice | Sleep | 2017 | 32 |
| 38 | Alprazolam, diazepam, yohimbine, clonidine: In vivo CA1, hippocampal norepinephrine and serotonin release profiles under chloral hydrate anesthesia | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 1997 | 30 |
| 39 | NO-donating aspirin inhibits the growth of leukemic Jurkat cells and modulates β-catenin expression | Biochemical and Biophysical Research Communications | 2004 | 30 |
| 40 | Comparison between 3-Nitrooxyphenyl acetylsalicylate (NO-ASA) andO2-(acetylsalicyloxymethyl)-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (NONO-ASA) as Safe Anti-Inflammatory, Analgesic, Antipyretic, Antioxidant Prodrugs | Journal of Pharmacology and Experimental Therapeutics | 2010 | 30 |
| 41 | Hydrogen sulfide-releasing aspirin modulates xenobiotic metabolizing enzymes in vitro and in vivo | Biochemical Pharmacology | 2012 | 29 |
| 42 | Acute and subacute effects of risperidone and cocaine on accumbens dopamine and serotonin release using in vivo microvoltammetry on line with open-field behavior | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2003 | 28 |
| 43 | Biogenic amines in the human neocortex in patients with neocortical and mesial temporal lobe epilepsy: identification with in situ microvoltammetry | Brain Research | 2001 | 27 |
| 44 | Early impairment of synaptic plasticity in patients with Down's syndrome | Neurobiology of Aging | 2008 | 26 |
| 45 | Motor cortex abnormalities in amyotrophic lateral sclerosis with transcranial direct-current stimulation | Muscle and Nerve | 2007 | 25 |
| 46 | Cannabinoid-induced tolerance is associated with a CB1 receptor G protein coupling switch that is prevented by ultra-low dose rimonabant | Behavioural Pharmacology | 2007 | 23 |
| 47 | Cortical plasticity and levodopa-induced dyskinesias in Parkinson’s disease: Connecting the dots in a multicomponent network | Clinical Neurophysiology | 2017 | 23 |
| 48 | Art therapy for Parkinson's disease | Parkinsonism and Related Disorders | 2021 | 22 |
| 49 | Brain dysfunction in uremia: a question of cortical hyperexcitability? | Clinical Neurophysiology | 2005 | 21 |
| 50 | Clozapine and cocaine effects on dopamine and serotonin release in nucleus accumbens during psychostimulant behavior and withdrawal | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2004 | 20 |
