The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints | Cancer Discovery | 2015 | 890 |
Family income, parental education and brain structure in children and adolescents | Nature Neuroscience | 2015 | 686 |
High Efficiency, Homology-Directed Genome Editing in Caenorhabditis elegans Using CRISPR-Cas9 Ribonucleoprotein Complexes | Genetics | 2015 | 322 |
BRCA1, BRCA2, PALB2, and CDKN2A mutations in familial pancreatic cancer: a PACGENE study | Genetics in Medicine | 2015 | 175 |
High Incidence of Noonan Syndrome Features Including Short Stature and Pulmonic Stenosis in Patients carrying NF1 Missense Mutations Affecting p.Arg1809: Genotype-Phenotype Correlation | Human Mutation | 2015 | 112 |
Bestrophin 1 is indispensable for volume regulation in human retinal pigment epithelium cells | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 92 |
Genomic Foundation of Starch-to-Lipid Switch in Oleaginous Chlorella spp | Plant Physiology | 2015 | 89 |
Small-molecule-directed, efficient generation of retinal pigment epithelium from human pluripotent stem cells | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 87 |
Integrating mRNA and miRNA Weighted Gene Co-Expression Networks with eQTLs in the Nucleus Accumbens of Subjects with Alcohol Dependence | PLoS ONE | 2015 | 52 |
Differential DNA methylation identified in the blood and retina of AMD patients | Epigenetics | 2015 | 46 |
Intrinsic biocontainment: multiplex genome safeguards combine transcriptional and recombinational control of essential yeast genes | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 43 |
Plasma Biomarkers of Brain Injury as Diagnostic Tools and Outcome Predictors After Extracorporeal Membrane Oxygenation | Critical Care Medicine | 2015 | 36 |
Demographic differences in willingness to provide broad and narrow consent for biobank research | Biopreservation and Biobanking | 2015 | 31 |
Impact of saline irrigation and topical corticosteroids on the postsurgical sinonasal microbiota | International Forum of Allergy and Rhinology | 2015 | 30 |
Determinants of Aortic Root Dilatation and Reference Values Among Young Adults Over a 20-Year Period: Coronary Artery Risk Development in Young Adults Study | Hypertension | 2015 | 29 |
Thioredoxin rod-derived cone viability factor protects against photooxidative retinal damage | Free Radical Biology and Medicine | 2015 | 24 |
Brain white matter volume abnormalities in Lesch-Nyhan disease and its variants | Neurology | 2015 | 23 |
Benign outcome among positive cystic fibrosis newborn screen children with non-CF-causing variants | Journal of Cystic Fibrosis | 2015 | 22 |
DISTMIX: direct imputation of summary statistics for unmeasured SNPs from mixed ethnicity cohorts | Bioinformatics | 2015 | 17 |
JEPEG: a summary statistics based tool for gene-level joint testing of functional variants | Bioinformatics | 2015 | 15 |
Validation of candidate anxiety disorder genes using a carbon dioxide challenge task | Biological Psychology | 2015 | 14 |
Reduced PLP2 expression increases ER-stress-induced neuronal apoptosis and risk for adverse neurological outcomes after hypoxia ischemia injury | Human Molecular Genetics | 2015 | 13 |
Identification and functional studies of regulatory variants responsible for the association of with a delusion phenotype in schizophrenia | Molecular Neuropsychiatry | 2015 | 12 |
ATXN2 is a modifier of phenotype in ALS patients of Sardinian ancestry | Neurobiology of Aging | 2015 | 10 |
Expression quantitative trait loci (eQTLs) in microRNA genes are enriched for schizophrenia and bipolar disorder association signals | Psychological Medicine | 2015 | 9 |