| # | Title | Journal | Year | Citations |
|---|
| 1 | Potential metal-binding domains in nucleic acid binding proteins | Science | 1986 | 1,219 |
| 2 | Predicting the secondary structure of globular proteins using neural network models | Journal of Molecular Biology | 1988 | 1,125 |
| 3 | Diffusion of Macromolecules and Virus-Like Particles in Human Cervical Mucus | Biophysical Journal | 2001 | 476 |
| 4 | Electron Microscopy of the Sperm Tail Results Obtained with a New Fixative | Journal of Cell Biology | 1959 | 455 |
| 5 | Associative long-term depression in the hippocampus induced by hebbian covariance | Nature | 1989 | 450 |
| 6 | Cytochalasin D inhibits actin polymerization and induces depolymerization of actin filaments formed during platelet shape change | Nature | 1981 | 421 |
| 7 | mRNA structure determines specificity of a polyQ-driven phase separation | Science | 2018 | 421 |
| 8 | Visual Pigments of Single Primate Cones | Science | 1964 | 413 |
| 9 | Large shifts in pK a values of lysine residues buried inside a protein | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 379 |
| 10 | Computational neuroscience | Science | 1988 | 377 |
| 11 | Network model of shape-from-shading: neural function arises from both receptive and projective fields | Nature | 1988 | 372 |
| 12 | The anatomy of the T5 bacteriophage DNA molecule | Journal of Molecular Biology | 1966 | 359 |
| 13 | Parallel visual computation | Nature | 1983 | 356 |
| 14 | The role of lactic acid production by probiotic Lactobacillus species in vaginal health | Research in Microbiology | 2017 | 336 |
| 15 | Cavities determine the pressure unfolding of proteins | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 329 |
| 16 | Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 321 |
| 17 | Enzyme Kinetics Determined Using Calorimetry: A General Assay for Enzyme Activity? | Analytical Biochemistry | 2001 | 313 |
| 18 | High Apparent Dielectric Constants in the Interior of a Protein Reflect Water Penetration | Biophysical Journal | 2000 | 295 |
| 19 | In vaginal fluid, bacteria associated with bacterial vaginosis can be suppressed with lactic acid but not hydrogen peroxide | BMC Infectious Diseases | 2011 | 284 |
| 20 | Crystal Structure of a Conserved Ribosomal Protein-RNA Complex | Science | 1999 | 271 |
| 21 | The crystal structure of the ternary complex of staphylococcal nuclease, Ca2+ and the inhibitor pdTp, refined at 1.65 Å | Proteins: Structure, Function and Bioinformatics | 1989 | 262 |
| 22 | Arginine: Its pKa value revisited | Protein Science | 2015 | 262 |
| 23 | Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography | Nature | 2017 | 251 |
| 24 | An Astable Multivibrator Model of Binocular Rivalry | Perception | 1988 | 241 |
| 25 | Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis | Frontiers in Physiology | 2015 | 240 |
| 26 | Experimental measurement of the effective dielectric in the hydrophobic core of a protein | Biophysical Chemistry | 1997 | 238 |
| 27 | A Neural Model of Figure–Ground Organization | Journal of Neurophysiology | 2007 | 231 |
| 28 | Estimation of changes in side chain configurational entropy in binding and folding: General methods and application to helix formation | Proteins: Structure, Function and Bioinformatics | 1994 | 224 |
| 29 | Mucus Penetrating Nanoparticles: Biophysical Tool and Method of Drug and Gene Delivery | Advanced Materials | 2012 | 223 |
| 30 | Learned classification of sonar targets using a massively parallel network | IEEE Transactions on Acoustics, Speech, and Signal Processing | 1988 | 203 |
| 31 | Charges in the hydrophobic interior of proteins | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 195 |
| 32 | Experimental pKa Values of Buried Residues: Analysis with Continuum Methods and Role of Water Penetration | Biophysical Journal | 2002 | 193 |
| 33 | TDP-43 represses cryptic exon inclusion in the FTD–ALS gene UNC13A | Nature | 2022 | 193 |
| 34 | Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia | Nature Genetics | 2020 | 180 |
| 35 | Specific interaction of vinculin with α-actinin | Biochemical and Biophysical Research Communications | 1987 | 178 |
| 36 | Structural basis for biosynthetic programming of fungal aromatic polyketide cyclization | Nature | 2009 | 176 |
| 37 | Specificity in transmembrane helix-helix interactions can define a hierarchy of stability for sequence variants | Proceedings of the National Academy of Sciences of the United States of America | 2001 | 172 |
| 38 | Rapid DNA–protein cross-linking and strand scission by an abasic site in a nucleosome core particle | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 170 |
| 39 | Vaginal lactic acid elicits an anti-inflammatory response from human cervicovaginal epithelial cells and inhibits production of pro-inflammatory mediators associated with HIV acquisition | Mucosal Immunology | 2017 | 158 |
| 40 | Real-time observation of DNA target interrogation and product release by the RNA-guided endonuclease CRISPR Cpf1 (Cas12a) | Proceedings of the National Academy of Sciences of the United States of America | 2018 | 156 |
| 41 | Terminal repetition in non-permuted T3 and T7 bacteriophage DNA molecules | Journal of Molecular Biology | 1967 | 153 |
| 42 | FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices | ELife | 2021 | 152 |
| 43 | Organ-specific autoimmune disease induced in mice by elimination of T cell subsets. V. Neonatal administration of cyclosporin A causes autoimmune disease. | Journal of Immunology | 1989 | 151 |
| 44 | Molecular determinants of the pKa values of Asp and Glu residues in staphylococcal nuclease | Proteins: Structure, Function and Bioinformatics | 2009 | 150 |
| 45 | Structure Activity Relationship of Dendrimer Microbicides with Dual Action Antiviral Activity | PLoS ONE | 2010 | 147 |
| 46 | Kinetics of biosynthesis of acetylcholine receptor and subsequent incorporation into plasma membrane of cultured chick skeletal muscle | Cell | 1977 | 143 |
| 47 | Enhanced Trapping of HIV-1 by Human Cervicovaginal Mucus Is Associated with Lactobacillus crispatus-Dominant Microbiota | MBio | 2015 | 141 |
| 48 | Rapid fluctuation of the vaginal microbiota measured by Gram stain analysis | Sexually Transmitted Infections | 2010 | 136 |
| 49 | Arginine residues at internal positions in a protein are always charged | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 136 |
| 50 | Neural model of stereoacuity and depth interpolation based on a distributed representation of stereo disparity [published erratum appears in J Neurosci 1991 Mar;11(3):following Table of Contents] | Journal of Neuroscience | 1990 | 135 |
