| # | Title | Journal | Year | Citations |
|---|
| 1 | The Genomic Landscapes of Human Breast and Colorectal Cancers | Science | 2007 | 3,049 |
| 2 | Sparse Subspace Clustering: Algorithm, Theory, and Applications | IEEE Transactions on Pattern Analysis and Machine Intelligence | 2013 | 2,282 |
| 3 | Cells lying on a bed of microneedles: An approach to isolate mechanical force | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 1,762 |
| 4 | Load Independence of the Instantaneous Pressure-Volume Ratio of the Canine Left Ventricle and Effects of Epinephrine and Heart Rate on the Ratio | Circulation Research | 1973 | 1,711 |
| 5 | The Ikappa B-NF-kappa B Signaling Module: Temporal Control and Selective Gene Activation | Science | 2002 | 1,672 |
| 6 | A comparative encyclopedia of DNA elements in the mouse genome | Nature | 2014 | 1,444 |
| 7 | Biomedical applications of polymer-composite materials: a review | Composites Science and Technology | 2001 | 1,260 |
| 8 | Eye movements evoked by collicular stimulation in the alert monkey | Vision Research | 1972 | 1,233 |
| 9 | The complete sequence of a human genome | Science | 2022 | 1,222 |
| 10 | The Rosetta All-Atom Energy Function for Macromolecular Modeling and Design | Journal of Chemical Theory and Computation | 2017 | 1,032 |
| 11 | Information Transduction Capacity of Noisy Biochemical Signaling Networks | Science | 2011 | 1,007 |
| 12 | Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment | Nature Medicine | 2017 | 994 |
| 13 | Neural Correlates of Motor Memory Consolidation | Science | 1997 | 918 |
| 14 | Transcriptome assembly from long-read RNA-seq alignments with StringTie2 | Genome Biology | 2019 | 897 |
| 15 | Consolidation in human motor memory | Nature | 1996 | 883 |
| 16 | Near-infrared deep brain stimulation via upconversion nanoparticle–mediated optogenetics | Science | 2018 | 856 |
| 17 | Detecting DNA cytosine methylation using nanopore sequencing | Nature Methods | 2017 | 820 |
| 18 | Learning of action through adaptive combination of motor primitives | Nature | 2000 | 818 |
| 19 | Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis | Nature Medicine | 2013 | 780 |
| 20 | Variable cytocompatibility of six cell lines with photoinitiators used for polymerizing hydrogels and cell encapsulation | Biomaterials | 2005 | 760 |
| 21 | Generalized principal component analysis (GPCA) | IEEE Transactions on Pattern Analysis and Machine Intelligence | 2005 | 752 |
| 22 | Accumulation of driver and passenger mutations during tumor progression | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 742 |
| 23 | Particle Tracking Microrheology of Complex Fluids | Physical Review Letters | 1997 | 738 |
| 24 | Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms | Nature | 2002 | 724 |
| 25 | MICROCIRCULATION AND HEMORHEOLOGY | Annual Review of Fluid Mechanics | 2005 | 674 |
| 26 | Coding of Border Ownership in Monkey Visual Cortex | Journal of Neuroscience | 2000 | 660 |
| 27 | Natural polymers for gene delivery and tissue engineering☆ | Advanced Drug Delivery Reviews | 2006 | 631 |
| 28 | Dissociating the Roles of the Cerebellum and Motor Cortex during Adaptive Learning: The Motor Cortex Retains What the Cerebellum Learns | Cerebral Cortex | 2011 | 617 |
| 29 | Multifunctional chondroitin sulphate for cartilage tissue–biomaterial integration | Nature Materials | 2007 | 609 |
| 30 | Functional Stages in the Formation of Human Long-Term Motor Memory | Journal of Neuroscience | 1997 | 603 |
| 31 | Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 585 |
| 32 | Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 576 |
| 33 | Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas | Nature Genetics | 2013 | 564 |
| 34 | Neural Correlates of Reach Errors | Journal of Neuroscience | 2005 | 550 |
| 35 | Telomere-to-telomere assembly of a complete human X chromosome | Nature | 2020 | 549 |
| 36 | E-cadherin is required for metastasis in multiple models of breast cancer | Nature | 2019 | 544 |
| 37 | Nanoscale cues regulate the structure and function of macroscopic cardiac tissue constructs | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 541 |
| 38 | Matrix nanotopography as a regulator of cell function | Journal of Cell Biology | 2012 | 522 |
| 39 | Engineering Complex Tissues | Tissue Engineering | 2006 | 513 |
| 40 | Defining the disease liability of variants in the cystic fibrosis transmembrane conductance regulator gene | Nature Genetics | 2013 | 513 |
| 41 | Addressing the PEG Mucoadhesivity Paradox to Engineer Nanoparticles that “Slip” through the Human Mucus Barrier | Angewandte Chemie - International Edition | 2008 | 503 |
| 42 | Cell shape provides global control of focal adhesion assembly | Biochemical and Biophysical Research Communications | 2003 | 501 |
| 43 | DNA-polycation nanospheres as non-viral gene delivery vehicles | Journal of Controlled Release | 1998 | 494 |
| 44 | Mechanics of Living Cells Measured by Laser Tracking Microrheology | Biophysical Journal | 2000 | 476 |
| 45 | GFF Utilities: GffRead and GffCompare | F1000Research | 2020 | 469 |
| 46 | Cancer cell motility: lessons from migration in confined spaces | Nature Reviews Cancer | 2017 | 465 |
| 47 | Design of a synthetic yeast genome | Science | 2017 | 464 |
| 48 | Major Impacts of Widespread Structural Variation on Gene Expression and Crop Improvement in Tomato | Cell | 2020 | 464 |
| 49 | Electric field and stimulating influence generated by deep brain stimulation of the subthalamic nucleus | Clinical Neurophysiology | 2004 | 455 |
| 50 | The effect of incorporating RGD adhesive peptide in polyethylene glycol diacrylate hydrogel on osteogenesis of bone marrow stromal cells | Biomaterials | 2005 | 434 |
