| # | Title | Journal | Year | Citations |
|---|
| 1 | NITRIC OXIDE: A Physiologic Messenger Molecule | Annual Review of Biochemistry | 1994 | 2,175 |
| 2 | Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues. | Proceedings of the National Academy of Sciences of the United States of America | 1991 | 1,650 |
| 3 | From circuits to behaviour in the amygdala | Nature | 2015 | 1,508 |
| 4 | Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase | Neuron | 1991 | 1,390 |
| 5 | β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression | Nature | 2005 | 1,379 |
| 6 | RAFT1: A mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs | Cell | 1994 | 1,355 |
| 7 | Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation | Nature | 1989 | 1,019 |
| 8 | Gases as biological messengers: nitric oxide and carbon monoxide in the brain | Journal of Neuroscience | 1994 | 994 |
| 9 | The C9orf72 repeat expansion disrupts nucleocytoplasmic transport | Nature | 2015 | 835 |
| 10 | Primate motor cortex and free arm movements to visual targets in three- dimensional space. II. Coding of the direction of movement by a neuronal population | Journal of Neuroscience | 1988 | 791 |
| 11 | RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention | Neuron | 2013 | 785 |
| 12 | C9orf72 nucleotide repeat structures initiate molecular cascades of disease | Nature | 2014 | 779 |
| 13 | The other side of the engram: experience-driven changes in neuronal intrinsic excitability | Nature Reviews Neuroscience | 2003 | 743 |
| 14 | Electrical and synaptic integration of glioma into neural circuits | Nature | 2019 | 706 |
| 15 | Sensory Neuron-Specific GPCR Mrgprs Are Itch Receptors Mediating Chloroquine-Induced Pruritus | Cell | 2009 | 681 |
| 16 | Biological Roles of Nitric Oxide | Scientific American | 1992 | 669 |
| 17 | Colocalization of neuropeptide Y immunoreactivity in brainstem catecholaminergic neurons that project to the paraventricular nucleus of the hypothalamus | Journal of Comparative Neurology | 1985 | 646 |
| 18 | Neurodegeneration in Excitotoxicity, Global Cerebral Ischemia, and Target Deprivation: A Perspective on the Contributions of Apoptosis and Necrosis | Brain Research Bulletin | 1998 | 621 |
| 19 | NMDA Induces Long-Term Synaptic Depression and Dephosphorylation of the GluR1 Subunit of AMPA Receptors in Hippocampus | Neuron | 1998 | 617 |
| 20 | Dissociating the Roles of the Cerebellum and Motor Cortex during Adaptive Learning: The Motor Cortex Retains What the Cerebellum Learns | Cerebral Cortex | 2011 | 617 |
| 21 | Solubilization, purification, and characterization of an inositol trisphosphate receptor. | Journal of Biological Chemistry | 1988 | 612 |
| 22 | Behavioural abnormalities in male mice lacking neuronal nitric oxide synthase | Nature | 1995 | 606 |
| 23 | SynGAP: a Synaptic RasGAP that Associates with the PSD-95/SAP90 Protein Family | Neuron | 1998 | 585 |
| 24 | Nitric oxide synthase regulatory sites. Phosphorylation by cyclic AMP-dependent protein kinase, protein kinase C, and calcium/calmodulin protein kinase; identification of flavin and calmodulin binding sites. | Journal of Biological Chemistry | 1992 | 558 |
| 25 | Clustering of AMPA Receptors by the Synaptic PDZ Domain–Containing Protein PICK1 | Neuron | 1999 | 523 |
| 26 | Purified inositol 1,4,5-trisphosphate receptor mediates calcium flux in reconstituted lipid vesicles | Nature | 1989 | 521 |
| 27 | Phosphorylation of the AMPA Receptor Subunit GluR2 Differentially Regulates Its Interaction with PDZ Domain-Containing Proteins | Journal of Neuroscience | 2000 | 509 |
| 28 | Primate motor cortex and free arm movements to visual targets in three- dimensional space. I. Relations between single cell discharge and direction of movement | Journal of Neuroscience | 1988 | 505 |
| 29 | Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity | Journal of Neuroscience | 1988 | 500 |
| 30 | The Koniocellular Pathway in Primate Vision | Annual Review of Neuroscience | 2000 | 492 |
| 31 | Poly (ADP-ribose) polymerase, nitric oxide and cell death | Trends in Pharmacological Sciences | 1999 | 486 |
| 32 | Haem oxygenase-1 prevents cell death by regulating cellular iron | Nature Cell Biology | 1999 | 484 |
| 33 | Responses to Contour Features in Macaque Area V4 | Journal of Neurophysiology | 1999 | 477 |
| 34 | Long-term synaptic depression in the mammalian brain | Neuron | 1994 | 475 |
| 35 | Synphilin-1 associates with α-synuclein and promotes the formation of cytosolic inclusions | Nature Genetics | 1999 | 473 |
| 36 | Differential immunohistochemical localization of inositol 1,4,5- trisphosphate- and ryanodine-sensitive Ca2+ release channels in rat brain | Journal of Neuroscience | 1993 | 462 |
| 37 | The blood-brain barrier: an engineering perspective | Frontiers in Neuroengineering | 2013 | 458 |
| 38 | PDZ Proteins Bind, Cluster, and Synaptically Colocalize with Eph Receptors and Their Ephrin Ligands | Neuron | 1998 | 438 |
| 39 | Surface Mobility of Postsynaptic AMPARs Tunes Synaptic Transmission | Science | 2008 | 433 |
| 40 | Shape Representation in Area V4: Position-Specific Tuning for Boundary Conformation | Journal of Neurophysiology | 2001 | 429 |
| 41 | Aberrant light directly impairs mood and learning through melanopsin-expressing neurons | Nature | 2012 | 424 |
| 42 | Inositol 1,4,5-Trisphosphate Receptors as Signal Integrators | Annual Review of Biochemistry | 2004 | 419 |
| 43 | Gating of social reward by oxytocin in the ventral tegmental area | Science | 2017 | 414 |
| 44 | Cortical mechanisms related to the direction of two-dimensional arm movements: relations in parietal area 5 and comparison with motor cortex | Experimental Brain Research | 1983 | 410 |
| 45 | Fast Nonnegative Deconvolution for Spike Train Inference From Population Calcium Imaging | Journal of Neurophysiology | 2010 | 404 |
| 46 | Flipping the Metabolic Switch: Understanding and Applying the Health Benefits of Fasting | Obesity | 2018 | 402 |
| 47 | The serotoninergic innervation of cerebral cortex: Different classes of axon terminals arise from dorsal and median raphe nuclei | Synapse | 1987 | 391 |
| 48 | Nitric Oxide in the Nervous System | Annual Review of Pharmacology and Toxicology | 1995 | 383 |
| 49 | Protein Topology of Presenilin 1 | Neuron | 1996 | 381 |
| 50 | Visual Attention: Bottom-Up Versus Top-Down | Current Biology | 2004 | 367 |
