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Top Articles

#TitleJournalYearCitations
1Cancer Genetics and Epigenetics: Two Sides of the Same Coin?Cancer Cell2012966
2Genome architectures revealed by tethered chromosome conformation capture and population-based modelingNature Biotechnology2012524
3Discovery of common and rare genetic risk variants for colorectal cancerNature Genetics2019377
4Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancersOncotarget2014367
5Environmental epigenetics: prospects for studying epigenetic mediation of exposure–response relationshipsHuman Genetics2012294
6Cell Surface Relocalization of the Endoplasmic Reticulum Chaperone and Unfolded Protein Response Regulator GRP78/BiPJournal of Biological Chemistry2010268
7Role of the unfolded protein response, GRP78 and GRP94 in organ homeostasisJournal of Cellular Physiology2015242
8Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysisNature Communications2020193
9Cancer Dormancy: A Model of Early Dissemination and Late Cancer RecurrenceClinical Cancer Research2012173
10Diagnosis and management of toxicities of immune checkpoint inhibitors in hepatocellular carcinomaJournal of Hepatology2020165
11Unique DNA Methylation Patterns Distinguish Noninvasive and Invasive Urothelial Cancers and Establish an Epigenetic Field Defect in Premalignant TissueCancer Research2010148
12Characterization and Mechanism of Stress-induced Translocation of 78-Kilodalton Glucose-regulated Protein (GRP78) to the Cell SurfaceJournal of Biological Chemistry2015139
13Genome-wide association study of colorectal cancer identifies six new susceptibility lociNature Communications2015138
14Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer RiskAmerican Journal of Human Genetics2020124
15Cancer Cells Resistant to Therapy Promote Cell Surface Relocalization of GRP78 Which Complexes with PI3K and Enhances PI(3,4,5)P3 ProductionPLoS ONE2013120
16OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genesProceedings of the National Academy of Sciences of the United States of America2011117
17Cumulative Burden of Colorectal Cancer–Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset CancerGastroenterology2020110
18DNMT3B isoforms without catalytic activity stimulate gene body methylation as accessory proteins in somatic cellsNature Communications2016109
19Circulating Tumor Cells Exhibit Metastatic Tropism and Reveal Brain Metastasis DriversCancer Discovery2020100
20The Development of the Calvarial Bones and Sutures and the Pathophysiology of CraniosynostosisCurrent Topics in Developmental Biology201590
21Outcome of children with multiply relapsed B-cell acute lymphoblastic leukemia: a therapeutic advances in childhood leukemia & lymphoma studyLeukemia201888
22Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancersNature Communications202075
23Margin width as the sole determinant of local recurrence after breast conservation in patients with ductal carcinoma in situ of the breastAmerican Journal of Surgery200669
24GRP78 as a regulator of liver steatosis and cancer progression mediated by loss of the tumor suppressor PTENOncogene201468
25Myeloid lineage switch following chimeric antigen receptor T‐cell therapy in a patient with TCF3‐ZNF384 fusion‐positive B‐lymphoblastic leukemiaPediatric Blood and Cancer201867
26The stress-inducible molecular chaperone GRP78 as potential therapeutic target for coronavirus infectionJournal of Infection202061
27GRP94 Regulates Circulating Cholesterol Levels through Blockade of PCSK9-Induced LDLR DegradationCell Reports201560
28Multiplex protein detection on circulating tumor cells from liquid biopsies using imaging mass cytometryConvergent Science Physical Oncology201860
29Microsatellite instability in colorectal cancer: overview of its clinical significance and novel perspectivesClinical Advances in Hematology and Oncology201859
30Phase 1 study of the anti-CD22 immunotoxin moxetumomab pasudotox for childhood acute lymphoblastic leukemiaBlood201757
31GLI3 repressor determines Hedgehog pathway activation and is required for response to SMO antagonist glasdegib in AMLBlood201756
32Liver-specific knockout of GRP94 in mice disrupts cell adhesion, activates liver progenitor cells, and accelerates liver tumorigenesisHepatology201455
33Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survivalNature Communications202055
34Cell competition in intratumoral and tumor microenvironment interactionsEMBO Journal202148
35Activator Protein-2 Overexpression Accounts for Increased Insulin Receptor Expression in Human Breast CancerCancer Research200647
36The Hydroxyquinoline Analogue YUM70 Inhibits GRP78 to Induce ER Stress–Mediated Apoptosis in Pancreatic CancerCancer Research202146
37A phase 1 study of azacitidine combined with chemotherapy in childhood leukemia: a report from the TACL consortiumBlood201844
38Genetic architectures of proximal and distal colorectal cancer are partly distinctGut202144
39SNF5 Is an Essential Executor of Epigenetic Regulation during DifferentiationPLoS Genetics201343
40SEER Cancer Registry Biospecimen Research: Yesterday and TomorrowCancer Epidemiology Biomarkers and Prevention201439
41Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestriesNature Genetics202339
42EPHB4 inhibition activates ER stress to promote immunogenic cell death of prostate cancer cellsCell Death and Disease201938
43Grp78 Heterozygosity Regulates Chaperone Balance in Exocrine Pancreas with Differential Response to Cerulein-Induced Acute PancreatitisAmerican Journal of Pathology201037
44Analyzing Circulating Tumor Cells One at a TimeTrends in Cell Biology201837
45Biomarker in Colorectal CancerCancer Journal (Sudbury, Mass )201635
46Targeting the glucose-regulated protein-78 abrogates Pten-null driven AKT activation and endometrioid tumorigenesisOncogene201534
47Metastasis Stemming from Circulating Tumor Cell ClustersTrends in Cell Biology201933
48TPL2/COT/MAP3K8 (TPL2) Activation Promotes Androgen Depletion-Independent (ADI) Prostate Cancer GrowthPLoS ONE201132
49A homozygousPMS2founder mutation with an attenuated constitutional mismatch repair deficiency phenotypeJournal of Medical Genetics201530
50Glucose-regulated protein 78 is essential for cardiac myocyte survivalCell Death and Differentiation201830