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Keck School of Medicine
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top-articles
Keck School of Medicine
113
(top 1%)
papers
6.1K
(top 1%)
citations
37
(top 1%)
h
-index
78
(top 1%)
g
-index
130
all documents
6.9K
doc citations
1.6K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Cancer Genetics and Epigenetics: Two Sides of the Same Coin?
Cancer Cell
2012
966
2
Genome architectures revealed by tethered chromosome conformation capture and population-based modeling
Nature Biotechnology
2012
524
3
Discovery of common and rare genetic risk variants for colorectal cancer
Nature Genetics
2019
377
4
Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers
Oncotarget
2014
367
5
Environmental epigenetics: prospects for studying epigenetic mediation of exposure–response relationships
Human Genetics
2012
294
6
Cell Surface Relocalization of the Endoplasmic Reticulum Chaperone and Unfolded Protein Response Regulator GRP78/BiP
Journal of Biological Chemistry
2010
268
7
Role of the unfolded protein response, GRP78 and GRP94 in organ homeostasis
Journal of Cellular Physiology
2015
242
8
Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis
Nature Communications
2020
193
9
Cancer Dormancy: A Model of Early Dissemination and Late Cancer Recurrence
Clinical Cancer Research
2012
173
10
Diagnosis and management of toxicities of immune checkpoint inhibitors in hepatocellular carcinoma
Journal of Hepatology
2020
165
11
Unique DNA Methylation Patterns Distinguish Noninvasive and Invasive Urothelial Cancers and Establish an Epigenetic Field Defect in Premalignant Tissue
Cancer Research
2010
148
12
Characterization and Mechanism of Stress-induced Translocation of 78-Kilodalton Glucose-regulated Protein (GRP78) to the Cell Surface
Journal of Biological Chemistry
2015
139
13
Genome-wide association study of colorectal cancer identifies six new susceptibility loci
Nature Communications
2015
138
14
Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk
American Journal of Human Genetics
2020
124
15
Cancer Cells Resistant to Therapy Promote Cell Surface Relocalization of GRP78 Which Complexes with PI3K and Enhances PI(3,4,5)P3 Production
PLoS ONE
2013
120
16
OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes
Proceedings of the National Academy of Sciences of the United States of America
2011
117
17
Cumulative Burden of Colorectal Cancer–Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer
Gastroenterology
2020
110
18
DNMT3B isoforms without catalytic activity stimulate gene body methylation as accessory proteins in somatic cells
Nature Communications
2016
109
19
Circulating Tumor Cells Exhibit Metastatic Tropism and Reveal Brain Metastasis Drivers
Cancer Discovery
2020
100
20
The Development of the Calvarial Bones and Sutures and the Pathophysiology of Craniosynostosis
Current Topics in Developmental Biology
2015
90
21
Outcome of children with multiply relapsed B-cell acute lymphoblastic leukemia: a therapeutic advances in childhood leukemia & lymphoma study
Leukemia
2018
88
22
Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers
Nature Communications
2020
75
23
Margin width as the sole determinant of local recurrence after breast conservation in patients with ductal carcinoma in situ of the breast
American Journal of Surgery
2006
69
24
GRP78 as a regulator of liver steatosis and cancer progression mediated by loss of the tumor suppressor PTEN
Oncogene
2014
68
25
Myeloid lineage switch following chimeric antigen receptor T‐cell therapy in a patient with TCF3‐ZNF384 fusion‐positive B‐lymphoblastic leukemia
Pediatric Blood and Cancer
2018
67
26
The stress-inducible molecular chaperone GRP78 as potential therapeutic target for coronavirus infection
Journal of Infection
2020
61
27
GRP94 Regulates Circulating Cholesterol Levels through Blockade of PCSK9-Induced LDLR Degradation
Cell Reports
2015
60
28
Multiplex protein detection on circulating tumor cells from liquid biopsies using imaging mass cytometry
Convergent Science Physical Oncology
2018
60
29
Microsatellite instability in colorectal cancer: overview of its clinical significance and novel perspectives
Clinical Advances in Hematology and Oncology
2018
59
30
Phase 1 study of the anti-CD22 immunotoxin moxetumomab pasudotox for childhood acute lymphoblastic leukemia
Blood
2017
57
31
GLI3 repressor determines Hedgehog pathway activation and is required for response to SMO antagonist glasdegib in AML
Blood
2017
56
32
Liver-specific knockout of GRP94 in mice disrupts cell adhesion, activates liver progenitor cells, and accelerates liver tumorigenesis
Hepatology
2014
55
33
Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival
Nature Communications
2020
55
34
Cell competition in intratumoral and tumor microenvironment interactions
EMBO Journal
2021
48
35
Activator Protein-2 Overexpression Accounts for Increased Insulin Receptor Expression in Human Breast Cancer
Cancer Research
2006
47
36
The Hydroxyquinoline Analogue YUM70 Inhibits GRP78 to Induce ER Stress–Mediated Apoptosis in Pancreatic Cancer
Cancer Research
2021
46
37
A phase 1 study of azacitidine combined with chemotherapy in childhood leukemia: a report from the TACL consortium
Blood
2018
44
38
Genetic architectures of proximal and distal colorectal cancer are partly distinct
Gut
2021
44
39
SNF5 Is an Essential Executor of Epigenetic Regulation during Differentiation
PLoS Genetics
2013
43
40
SEER Cancer Registry Biospecimen Research: Yesterday and Tomorrow
Cancer Epidemiology Biomarkers and Prevention
2014
39
41
Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries
Nature Genetics
2023
39
42
EPHB4 inhibition activates ER stress to promote immunogenic cell death of prostate cancer cells
Cell Death and Disease
2019
38
43
Grp78 Heterozygosity Regulates Chaperone Balance in Exocrine Pancreas with Differential Response to Cerulein-Induced Acute Pancreatitis
American Journal of Pathology
2010
37
44
Analyzing Circulating Tumor Cells One at a Time
Trends in Cell Biology
2018
37
45
Biomarker in Colorectal Cancer
Cancer Journal (Sudbury, Mass )
2016
35
46
Targeting the glucose-regulated protein-78 abrogates Pten-null driven AKT activation and endometrioid tumorigenesis
Oncogene
2015
34
47
Metastasis Stemming from Circulating Tumor Cell Clusters
Trends in Cell Biology
2019
33
48
TPL2/COT/MAP3K8 (TPL2) Activation Promotes Androgen Depletion-Independent (ADI) Prostate Cancer Growth
PLoS ONE
2011
32
49
A homozygousPMS2founder mutation with an attenuated constitutional mismatch repair deficiency phenotype
Journal of Medical Genetics
2015
30
50
Glucose-regulated protein 78 is essential for cardiac myocyte survival
Cell Death and Differentiation
2018
30
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